Elucidation of role of Rho-kinase in the post resuscitation syndrome
| Project/Area Number |
22591738
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Anesthesiology/Resuscitation studies
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| Research Institution | Nagasaki University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 心筋虚血再灌流障害 / 心筋スタニング / α_2アドレナリン受容体刺激薬 / phosphodiesterase-III阻害薬 / Rho-kinase阻害薬 / p38MAPK / 再灌流性不整脈 / α2-adrenergic agonist / カテコラミン / ホスホジエステラーゼIII阻害薬 / カルシウム感受性増強薬 / 薬理学的プレコンディショニング / 心筋梗塞サイズ / 水素 / ボスホジエステラーゼIII阻害薬 / 好中球エラスターゼ阻害薬 / サイトカイン |
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| Research Abstract |
Myocardial reperfusion injury is said to be an important factor of the postresuscitation myocardial dysfunction. The pharmacological control for the myocardial ischemiareperfusion injury leads to conquest of the postresuscitation myocardial dysfunction.
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Report
(4 results)
Research Products
(15 results)
