Analysis of the macrophage invaded in latent to occult prostate cancer
| Project/Area Number |
22591765
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Urology
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| Research Institution | Mie University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
SIRAISHI Taizou 三重大学, 大学院・医学系研究科, 教授 (30162762)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 腫瘍学 / 前立腺癌 / 炎症 / マクロファージ / 微小環境 / 微小癌 / 臨床癌 |
|---|
| Research Abstract |
In the clinical cancer specimen, tumor associated macrophage showed little involvment to latent prostate cancer. Alternative experiment has been developed that is in vitro experiment of cancer and macrophage interaction mimicking the microenvironment. Suppressive mechanism of prostate cancer was suggested againstinflammatory cell under TGFβ stimulation.
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Report
(4 results)
Research Products
(11 results)
