Project/Area Number |
22591789
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Urology
|
Research Institution | Hamamatsu University School of Medicine |
Principal Investigator |
NAGATA Masao 浜松医科大学, 医学部附属病院, 助教 (70397397)
|
Co-Investigator(Kenkyū-buntansha) |
OZONO Seiichiro 浜松医科大学, 医学部附属病院, 教授 (00183228)
TAKAYAMA Tatsuya 浜松医科大学, 医学部附属病院, 講師 (90324350)
|
Project Period (FY) |
2010 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
|
Keywords | 結石症学 / 尿路結石症 / 蓚酸 |
Research Abstract |
The activity of SPT/AGT can be measured by SGT activity also not only in a healthy person but in PH1 patient. The activity of GR can be measured by DGDH activity, in nine stone patients' average was 1.81±0.76 nmol/min/mg protein. L-Glycerate can be measured by HPLC used a chiral column. The comparison of L-Glycerate with 52 non-stone patients (non-stone former:non-SF) and nine stone patients (stone former:SF) , The value of SF was high with non-SF 13.3micromol/L, SF 21.3micromol/L, is a significant difference at the median.
|