Exploitation of noninvasive genetic diagnosis for therapy of male infertility
| Project/Area Number |
22591810
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Urology
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| Research Institution | Nagasaki International University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
WADA Morimasa 長崎国際大学, 薬学部, 教授 (20220965)
FUJIMOTO Kyoko 長崎国際大学, 薬学部, 助教 (50435137)
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| Co-Investigator(Renkei-kenkyūsha) |
TSUJIMURA Akira 大阪大学, 大学院・医学部, 准教授 (40294053)
MIYAGAWA Yasushi 大阪大学, 大学院・医学部, 准教授 (70362704)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
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| Keywords | Sperm / Testis / Infertility / Spermatogenesis / Germ cell / 精巣 / 精子 / 男性不妊 / 発生 / 遺伝子 / 蛋白質 / 特異的 / 治療 |
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| Research Abstract |
We developed the system which can identify 10% or more genetic factors of a male infertility by a microarray or PCR. On the other hand, we found out that the licorice which is a herbal medicine raised fertilization ability in a mouse. Next,it is a purpose to provide curative medicine based on male infertility DNA diagnosis.
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Report
(4 results)
Research Products
(53 results)
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[Journal Article] A Single Nucleotide Polymorphism within the Novel Sex-Linked Testis-Specific Retrotransposed PGAM42012
Author(s)
Okuda H, Tsujimura A, Irie S, Yamamoto K, Fukuhara S, Matsuoka Y, Takao T, Miyagawa Y, Nonomura N, Wada M, Tanaka H.
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Journal Title
Gene Influences Human Male Fertility. PLoS ONE
Volume: 7:e35195
Related Report
Peer Reviewed
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[Journal Article] Primary screening of single nucleotide polymorphisms in human calreticulin 3(CALR3).2011
Author(s)
Irie S, Nakamura J, Miyagawa Y, Tsujimura A, Okuda H, Yamamoto K, Fukuhara S, Yoshioka I, Hiroshi K, Matsuoka Y, Takao T, Nonomura N, Ikawa M, Tokuhiro K, Okabe M, Shibata T, Fujimoto K, Wada M, Tanaka H
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Journal Title
The Open Androl J
Volume: 3
Pages: 30-35
Related Report
Peer Reviewed
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