Clinical usefulness of human papillomavirus testing
Project/Area Number |
22591846
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Obstetrics and gynecology
|
Research Institution | University of Tsukuba |
Principal Investigator |
|
Co-Investigator(Renkei-kenkyūsha) |
YOSHIKAWA Hiroyuki 筑波大学, 医学医療系, 教授 (40158415)
|
Project Period (FY) |
2010 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
|
Keywords | ヒトパピローマウイルス / 子宮頸癌 / HPV / 子宮頸部上皮内腫瘍 / 子宮頸部異形成 / 中和抗体 / HPVタイプ / ヒトパピローマウイルスhuman papillomavirus(HPV) / 子宮頸癌cervical cancer / 子宮頸部上皮内腫瘍cervical intraepithelial neoplasia(CIN) / low-grade squamous intraepithelial lesion(LSIL) |
Research Abstract |
Infections by oncogenic human papillomaviruses (HPVs) are a major risk factor of cervical cancer. To evaluate the clinical usefulness of HPV DNA testing and serology, we analyzed follow-up data of 570 women with low-grade cervical lesions. Our findings suggested that HPV genotyping and antibody assays for women with low-grade cervical abnormalities may be useful for identifying populations at increased or decreased risk of disease progression.
|
Report
(4 results)
Research Products
(15 results)
-
-
[Journal Article] Do neutralizing antibody responses generated by human papillomavirus infections favor a better outcome of low-grade cervical lesions?2012
Author(s)
Ochi H, Matsumoto K, Kondo K, Oki A, Furuta R, Hirai Y, Yasugi T, Takatsuka N, Maeda H, Mitsuhashi A, Fujii T, Kawana K, Iwasaka T, Yaegashi N, Watanabe Y, Nagai Y, Kitagawa T, Kanda T, Yoshikawa H
-
Journal Title
J Med Virol
Volume: 84(7)
Issue: 7
Pages: 1128-1134
DOI
Related Report
Peer Reviewed
-
[Journal Article] HLA Class II DRB1*1302 1 allele protects against progression to cervical intraepithelial neoplasia grade 3:A multicenter, prospective, cohort study.2012
Author(s)
Matsumoto K, Maeda H, Oki A, Takatsuka N, Yasugi T, Furuta R, Hirata R, Mitsuhashi A, Fujii T, Hirai Y, Iwasaka T, Yaegashi N, Watanabe Y, Nagai Y, Kitagawa T, Yoshikawa H
-
Journal Title
Int J Gynecol Cancer
Volume: 22(3)
Issue: 3
Pages: 471-478
DOI
Related Report
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
-
-