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Construction of xenograft models of human endometrial cancer in NOD/SCID IL-2R gamma null mice

Research Project

Project/Area Number 22591847
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Obstetrics and gynecology
Research Institution公益財団法人がん研究会 (2012)
Chiba University (2010-2011)

Principal Investigator

KATO Kazuyoshi  公益財団法人がん研究会, 有明病院婦人科, 医長 (80399451)

Co-Investigator(Kenkyū-buntansha) SHOZU Makio  千葉大学, 医学研究科(研究院), 教授 (30226302)
MITSUHASHI Akira  千葉大学, 医学研究科(研究院), 准教授 (40302541)
ISHIKAWA Hiroshi  千葉大学, 医学研究科(研究院), 助教 (70553973)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords子宮内膜癌 / エストロゲン / 腎被膜下移植 / NOGマウス / 動物実験モデル
Research Abstract

We established the procedure of creating the xenograft models of human leiomyoa tissue in NOD/SCID IL-2R gamma null (NOG) mice. However, we could not reconstruct human endometrial cancer under the renal capsule of NOG mice

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (21 results)

All 2013 2012 2011 2010

All Journal Article (6 results) (of which Peer Reviewed: 6 results) Presentation (15 results)

  • [Journal Article] Bladder function after modified posterior exenteration for primary gynecological cancer2013

    • Author(s)
      Kazuyoshi Kato, Shinichi Tate, Kyoko Nishikimi, Makio Shozu
    • Journal Title

      Gynecol Oncol

      Volume: 129 Issue: 1 Pages: 229-233

    • DOI

      10.1016/j.ygyno.2013.01.013

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Secondary debulking surgery in ovarian cancer patients with isolated nodal recurrence located in the region above and behind the renal vein2013

    • Author(s)
      Kazuyoshi Kato, Kohei Omatsu, Nobuhiro Takeshima
    • Journal Title

      Gynecol Oncol

      Volume: 2 Issue: 1 Pages: 226-228

    • DOI

      10.1016/j.ygyno.2013.03.025

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Daily Low-Dose Cisplatin-Based Concurrent Chemoradiotherapy in Patients With Uterine Cervical Cancer With Emphasis on Elderly Patients: A Phase 2 Trial2012

    • Author(s)
      Mitsuhashi A, Uno T, Usui H, Nishikimi K, Yamamoto N, Watanabe M, Tate S, Hirashiki K, Kato K, Yamazawa K, Shozu M
    • Journal Title

      Int J Gynecol Cancer

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] The application of a newly developed linear stapler preloaded with the tissue reinforcement to distal pancreatectomy in the management of ovarian cancer2011

    • Author(s)
      Kazuyoshi Kato, Shinichi Tate, Takashi Uehara, Hirokazu Usui, Akira Mitsuhashi, Makio Shozu
    • Journal Title

      Eur J Gynaecol Oncol

      Volume: 32 Pages: 579-581

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] The application of a newly developed linear stapler preloaded with the tissue reinforcement to distal pancreatectomy in the management of ovarian cancer2011

    • Author(s)
      Kazuyoshi Kato, Shinichi Tate, Takashi Uehara, Hirokazu Usui, Akira Mitsuhashi, Makio Shozu
    • Journal Title

      European Journal of Gynaecological Oncology

      Volume: 32 Pages: 579-581

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Postoperative concurrent daily low-dose cisplatin-based chemoradiation improves the prognosis of patients with pathologic T2b or N1 cervical cancer2010

    • Author(s)
      Mitsuhashi A, Uno T, Usui H, Tate S, Hirashiki K, Kato K, Kiyohara H, Kato S, Ito H, Shozu M
    • Journal Title

      Anticancer Res

      Volume: 30 Pages: 2341-6

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Presentation] 症例検討パネルディスカッション06 「再発卵巣がんに対する集学的治療 傍大動脈リンパ節郭清の有効性を含めて」2012

    • Author(s)
      加藤一喜
    • Organizer
      第50回日本癌治療学会学術集会
    • Place of Presentation
      神奈川県横浜市
    • Related Report
      2012 Final Research Report
  • [Presentation] "SURGICAL ANATOMY OF THE COMMON ILIAC VEINS IN PARA-AORTIC LYMPHADENECTOMY IN GYNECOLOGICAL CANCER"2012

    • Author(s)
      Kazuyoshi Kato
    • Organizer
      The International Gynecologic Cancer Society (IGCS) 14th Biennial Meeting
    • Place of Presentation
      Vancouver, Canada
    • Related Report
      2012 Final Research Report
  • [Presentation] 「卵巣癌の骨盤部主病巣に対する根治術 -腹膜ごと摘出」2012

    • Author(s)
      加藤一喜
    • Organizer
      第35回日本産婦人科手術学会 要望講演 「卵巣癌患者の予後とQOL向上を目指して」
    • Place of Presentation
      京都府京都市
    • Related Report
      2012 Final Research Report
  • [Presentation] 「進行卵巣癌に対する完全切除を目指した手術療法の有効性と安全性の検討」2012

    • Author(s)
      加藤一喜
    • Organizer
      第52回日本婦人科腫瘍学会学術講演会
    • Place of Presentation
      東京都港区
    • Related Report
      2012 Final Research Report
  • [Presentation] 進行卵巣癌に対する完全切除を目指した手術療法の有効性と安全性の検討2012

    • Author(s)
      加藤 一喜
    • Organizer
      第52回日本婦人科腫瘍学会学術講演会
    • Place of Presentation
      東京都港区
    • Related Report
      2012 Annual Research Report
  • [Presentation] 卵巣癌の骨盤部主病巣に対する根治術 -腹膜ごと摘出2012

    • Author(s)
      加藤 一喜
    • Organizer
      第35回日本産婦人科手術学会
    • Place of Presentation
      京都府京都市
    • Related Report
      2012 Annual Research Report
  • [Presentation] 再発卵巣がんに対する集学的治療 傍大動脈リンパ節郭清の有効性を含めて2012

    • Author(s)
      加藤 一喜
    • Organizer
      第50回日本癌治療学会学術集会
    • Place of Presentation
      神奈川県横浜市
    • Related Report
      2012 Annual Research Report
  • [Presentation] SURGICAL ANATOMY OF THE COMMON ILIAC VEINS IN PARA-AORTIC LYMPHADENECTOMY IN GYNECOLOGICAL CANCER2012

    • Author(s)
      Kazuyoshi Kato
    • Organizer
      The International Gynecologic Cancer Society 14th Biennial Meeting
    • Place of Presentation
      Vancouver, Canada
    • Related Report
      2012 Annual Research Report
  • [Presentation] SURGICAL ANATOMY OF THE VAGINAL AND INFERIOR VESICAL ARTERIES IN NERVE-SPARING RADICAL HYSTERECTOMY2011

    • Author(s)
      Kazuyoshi Kato, K.Nishikimi, H.Usui, S.Tate, N.Yamamoto, K.Yamazawa, Akira Mitsuhashi, Makio Shozu
    • Organizer
      17th International Meeting Of The European Society Of Gynaecological Oncology
    • Place of Presentation
      Milan Convention Center(イタリア ミラノ)
    • Year and Date
      2011-09-12
    • Related Report
      2011 Annual Research Report
  • [Presentation] 骨盤自律神経温存広汎子宮全摘術における下膀胱動脈の臨床解剖学的検討2011

    • Author(s)
      加藤一喜、錦見恭子、三橋暁、生水真紀夫, 他
    • Organizer
      第50回日本婦人科腫瘍学会学術講演会
    • Place of Presentation
      札幌コンベンションセンター(北海道)
    • Year and Date
      2011-07-24
    • Related Report
      2011 Annual Research Report
  • [Presentation] "SURGICAL ANATOMY OF THE VAGINAL AND INFERIOR VESICAL ARTERIES IN NERVE-SPARING RADICAL HYSTERECTOMY"2011

    • Author(s)
      Kazuyoshi Kato
    • Organizer
      17th International Meeting of The European Society of Gynaecological Oncology (ESGO)
    • Place of Presentation
      Milan, Italy
    • Related Report
      2012 Final Research Report
  • [Presentation] 「骨盤自律神経温存広汎子宮全摘術における下膀胱動脈の臨床解剖学的検討」2011

    • Author(s)
      加藤一喜
    • Organizer
      第50回日本婦人科腫瘍学会学術講演会 ワークショップ5 「神経温存広汎子宮全摘術」
    • Place of Presentation
      北海道札幌市
    • Related Report
      2012 Final Research Report
  • [Presentation] 進行子宮体癌に対する手術療法の有効性と安全性の検討2010

    • Author(s)
      加藤一喜
    • Organizer
      日本婦人科腫瘍学会
    • Place of Presentation
      つくば国際会議場(茨城県)
    • Year and Date
      2010-07-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] 「再発卵巣癌に対する腫瘍減量手術の有効性と安全性の検討」2010

    • Author(s)
      加藤一喜
    • Organizer
      第48回日本癌治療学会学術集会 パネルディスカッション19 「再発卵巣がん治療:最先端を覗く」
    • Place of Presentation
      京都府京都市
    • Related Report
      2012 Final Research Report
  • [Presentation] 「進行子宮体癌に対する手術療法の有効性と安全性の検討」2010

    • Author(s)
      加藤一喜
    • Organizer
      第48回日本婦人科腫瘍学会学術講演会 ワークショップ2 「進行子宮体癌の集学的治療」
    • Place of Presentation
      茨城県つくば市
    • Related Report
      2012 Final Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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