Studies for accessing improvement of frequency selectivity by stimulating the auditory efferent systems

• Project/Area Number: 22591874
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Otorhinolaryngology
• Research Institution: Tohoku University
• Principal Investigator: HIDAKA Hiroshi 東北大学, 病院, 講師 (40302103)
• Co-Investigator(Kenkyū-buntansha): KAWASE Tetsuaki 東北大学, 大学院・医工学研究科, 教授 (50169728) ; SUGAWARA Mitsuru 東北大学, 大学院・医学系研究科, 非常勤講師 (40344668)
• Project Period (FY): 2010 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000); Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
• Keywords: 聴覚 / 神経生理学 / 周波数選択性 / 聴覚生理 / 遠心性経路

Research Abstract

Deterioration in frequency discrimination is one of the major factors contributing to inability to language discrimination. For accessing these problem, we firstly conducted establish of measuring frequency selectivity by measuring the compound action potential of auditory nerve using mice. Second, we investigated frequency tonotopisity in mice by imaging technique.

Research Products

• [Journal Article] Giant cell reparative granuloma of the temporal bone successfully resected withpreservation of hearing (2013)
  • Author(s): Takata Y, Hidaka H, Ishida K, Kobayashi T.
  • Journal Title: J Laryngol Otol
  • Peer Reviewed
• [Journal Article] Congenital cholesteatoma in predominantly found in the posterior-superior quadrant in the Asian population: systematic review and meta-analysis (2013)
  • Author(s): Hidaka H, Yamaguchi T, Miyazaki H, Nomura K, Kobayashi T.
  • Journal Title: Otol Neurotol Volume: 34 Pages: 630-638
  • Peer Reviewed
• [Journal Article] Masking effects in patients with auditory neuropathy-posible involvement of suppression mechanism caused by normal outer hair cell function- (2013)
  • Author(s): Oda K, Kawase T, Takata Y, Miyazaki H, Hidaka H, Kobayashi T.
  • Journal Title: Otol Neurotol
  • Peer Reviewed
• [Journal Article] Identification of Actinomyces meyeri Actinomycosis in middle ear and mastoid by 16S ribosomal RNA analysis (2013)
  • Author(s): Kakuta R, Hidaka H, Yano H, Miyazaki H, Suzaki H, Nakamura Y, Hirakata Y, Kaku M, Kobayashi T.
  • Journal Title: J Medical Microbiol
  • Peer Reviewed
• [Journal Article] Electrophysiological mapping of the cochlear nucleus with multi-channel bipolar surface microelectrodes (2013)
  • Author(s): Oda K, Kawase T, Yamauchi D, Hidaka H, Kobayashi T
  • Journal Title: Eur Arch Otolaryngol Volume: 270 Pages: 869-874
  • Peer Reviewed
• [Journal Article] Electrophysiological mapping of the cochlear nucleus with multi-channel bipolar surface microelectrodes. (2013)
  • Author(s): Oda K
  • Journal Title: Eur Arch Otolaryngol Volume: 270 Issue: 3 Pages: 869-974
  • DOI: 10.1007/s00405-012-2077-5
  • Peer Reviewed
• [Journal Article] Congenital cholesteatoma in predominantly found in the posterior-superior quadrant in the Asian population: systematic review and meta-analysis (2013)
  • Author(s): Hidaka H
  • Journal Title: Otology & Neurotology Volume: in press
  • Peer Reviewed
• [Journal Article] Masking effects in patients with auditory neuropathy-posible involvement of suppression mechanism caused by normal outer hair cell function- (2013)
  • Author(s): Oda K
  • Journal Title: Otology & Neurotology Volume: in press
  • Peer Reviewed
• [Journal Article] Traumatic pneumolabyrinth: air location and hearing outcomes (2012)
  • Author(s): Hidaka H, Miyazaki M, Kawase T, Kobayashi T.
  • Journal Title: Otol Neurotol Volume: 33 Pages: 123-131
  • Peer Reviewed
• [Journal Article] Surgical treatment for congenital absence of the oval window with facial nerve anomalies (2012)
  • Author(s): Hasegawa T, Kawase T, Hidaka H, Oshima T, Kobayashi T.
  • Journal Title: Auris Nasus Larynx Volume: 39 Pages: 249-255
  • Peer Reviewed
• [Journal Article] Petrous bone cholesteatoma removed by trans-superior semicircular canal approach: Long-term hearing results in threecases (2012)
  • Author(s): Hasegawa T, Kawase T, Hidaka H, Oshima T, Kobayashi T.
  • Journal Title: Acta Otolaryngol Volume: 132 Pages: 896-902
  • Peer Reviewed
• [Journal Article] Traumatic pneumolabyrinth: air location and hearing outcomes (2012)
  • Author(s): Hidaka H
  • Journal Title: Otology & Neurotology Volume: 33 Issue: 2 Pages: 123-131
  • DOI: 10.1097/mao.0b013e318241bc91
  • Peer Reviewed
• [Journal Article] Surgical treatment for congenital absence of the oval window with facial nerve anomalies (2012)
  • Author(s): Hasegawa J
  • Journal Title: Auris Nusus Larynx Volume: 39 Issue: 2 Pages: 896-902
  • DOI: 10.1016/j.anl.2011.04.016
  • Peer Reviewed
• [Journal Article] Petrous bone cholesteatoma removed by trans-superior semicircular canal approach: Long-term hearing results in three cases. (2012)
  • Author(s): Hasegawa J
  • Journal Title: Acta Otolaryngol Volume: 132 Pages: 896-902
  • DOI: 10.3109/00016489.2011.653444
  • Peer Reviewed
• [Journal Article] Traumatic pneumolabyrinth : air location and hearing outcomes (2012)
  • Author(s): Hidaka H, Miyazaki M, Kawase T, Kobayashi T
  • Journal Title: Otol Neurotol Volume: 33 Pages: 123-131
  • Peer Reviewed
• [Journal Article] Precipitating factors in the pathogenesis of peritonsillar abscess and bacteriological significance of the Streptococcus Milleri Group (2011)
  • Author(s): Hidaka H, Kuriyama S, Yano H, Tsuji I, Kobayashi T
  • Journal Title: Eur J Clinical Mictrobiol Volume: 30 Pages: 527-532
  • Peer Reviewed
• [Journal Article] An analysis of clinical risk factors of deep neck infection (2011)
  • Author(s): Hasegawa J, Hidaka H, Tateda M, et al
  • Journal Title: Auris Nasus Larynx Volume: 38 Pages: 101-107
  • Peer Reviewed
• [Journal Article] Congenital cholesteatoma of the mastoid region manifesting as acute mastoiditis and a review of the literature (2010)
  • Author(s): Hidaka H, Iahida E, et al
  • Journal Title: Journal of Laryngology and Otology Volume: 124 Pages: 810-815
  • Peer Reviewed
• [Journal Article] Osteochondroma of the mandibular condyle manifesting only as conductive hearing loss (2010)
  • Author(s): Hidaka H, Kobayashi T, et al
  • Journal Title: Otolaryngology Head and Neck Surgery Volume: 143 Pages: 710-711
  • Peer Reviewed
• [Presentation] Masking effects in patients with auditory neuropathy: possible involvement of suppression mechanism cuased by normal outer hair cell function (2013)
  • Author(s): Oda H, Kawase T, Takata Y, Miyazaki H, Hidaka H, et al
  • Organizer: Abstract of the 36^<th> ARO meeting of the Association for Research in Otolaryngology: pp. 198
  • Place of Presentation: Baltimore, USA
• [Presentation] Masking by lower-level broadband noise observed in patients with auditory neuropathy (2012)
  • Author(s): Oda K, Kawase T, Hidaka H et al
  • Organizer: Abstract of the 1^<st> Asian Otology Meeting & 3^<rd> East Asian Symposium on Otology: pp. 58
  • Place of Presentation: Nagasaki, Japan
  • Year and Date: 2012-06-02
• [Presentation] Pneumolabyrinth associated with ear trauma: gas bubble location and hearing outcomes (2012)
  • Author(s): Hidaka H, Miyazaki M, Kawase T, Kobayashi T.
  • Organizer: Abstract of the 1^<st> Asian Otology Meeting & 3^<rd> East Asian Symposium on Otology: pp. 44
  • Place of Presentation: Nagasaki, Japan
  • Year and Date: 2012-06-02
• [Presentation] Petrous bone cholesteatoma removed by trans-superior semicircular canal approach: long-term hearing results in three patients (2012)
  • Author(s): Miyazaki H, Hasegawa J, Takata Y, Oshima T, Hidaka H, et al
  • Organizer: Abstract of the 9^<th> International Conference on Cholesteatoma and Ear Surgery: pp. 333
  • Place of Presentation: Nagasaki, Japan
• [Presentation] Actinomycosis of the middle ear: identification of Actinomyces meyeri using 16S rRNA analysis (2012)
  • Author(s): Kakuta R, Hidaka H, Yano H, et al
  • Organizer: Abstract of the 9^<th> International Conference on Cholesteatoma and Ear Surgery: pp. 296
  • Place of Presentation: Nagasaki, Japan
• [Presentation] Congenital cholesteatoma is predominantly found in the PSQ in the Asian population (2012)
  • Author(s): Hidaka H, Kobayashi T.
  • Organizer: Abstract of the 9^<th> International Conference on Cholesteatoma and Ear Surgery: pp. 269
  • Place of Presentation: Nagasaki, Japan
• [Presentation] Petrous bone cholesteatoma removed by trans-superior semicircular canal approach (2012)
  • Author(s): Kobayashi T, Hasegawa J, Takata Y, Miyazaki H, Oshima T, Hidaka H, et al
  • Organizer: Abstract of the 14^<th> Japan-Korea Joint Meeting of otolaryngology-Head and Neck Surgery: pp. 119
  • Place of Presentation: Kyoto, Japan
• [Presentation] Traumatic pneumolabyrinth: air location and hearing outcome (2012)
  • Author(s): Hidaka H, Miyazaki M, Kawase T, et al
  • Organizer: Abstract of the 14^<th> Japan-Korea Joint Meeting of otolaryngology-Head and Neck Surgery: pp. 100
  • Place of Presentation: Kyoto, Japan
• [Presentation] TraumaticｐPneumolabyrinth：air location and hearing outcome (2012)
  • Author(s): 日高浩史
  • Organizer: The 14th Japan-Korea Joint Meeting of otolaryngology-Head and Neck Surgery
  • Place of Presentation: 京都
• [Presentation] Pneumolabyrinth associated with ear trauma: gas bubble location and hearing outcomes. (2012)
  • Author(s): 日高浩史
  • Organizer: The 1st Asian Otology Meeting & 3rd East Asian Symposium on Otology
  • Place of Presentation: 長崎
  • Invited
• [Presentation] Congenital Cholesteatoma is Dominantly Found at the Posterior-superior Quadrant in Asian Population: Our Experience and Meta-analysis (2012)
  • Author(s): 日高浩史
  • Organizer: The 9 th Internarional Conference on Cholesteatoma and Ear Surgery
  • Place of Presentation: 長崎
• [Presentation] ワークショップ４：診断治療難治例 気道異物の入院加療期間を左右する因子について (2012)
  • Author(s): 日高浩史
  • Organizer: 第64回日本気管食道科学会 総会学術講演会
  • Place of Presentation: 東京
  • Invited
• [Presentation] 鼓膜張筋腱切断術で耳鳴が消失した中耳ミオクローヌスの１症例 (2012)
  • Author(s): 日高浩史
  • Organizer: 第57回 日本聴覚医学会
  • Place of Presentation: 京都
• [Presentation] 先天性真珠腫の発生部位の国際的地域差について～システック・レビューとメタ分析からみて～ (2012)
  • Author(s): 日高浩史
  • Organizer: 第22回 日本耳科学会
  • Place of Presentation: 名古屋
• [Presentation] パネルデスカッション:先天性真珠腫治療のプランニング (2011)
  • Author(s): 日高浩史
  • Organizer: 日本耳科学会総会・学術講演会
  • Place of Presentation: 沖縄(招待講演)
  • Year and Date: 2011-11-26
• [Presentation] Sinonasal inverted papilloma: importance of preoperative diagnosis, time to recurrence, and recurrence site (2011)
  • Author(s): Nishikawa H, Hidaka H, Ishida E.
  • Organizer: Abstract of the 11^<th> Japan-Taiwan Conference on Otolaryngology-Head and Neck Surgery: pp. 231
  • Place of Presentation: Kobe, Japan
• [Presentation] Unique inhaled foreign body in a pediatric patients: fried chicken in the tracheobronchial tree complicated with severe pulmonary reactions (2011)
  • Author(s): Hidaka H, Suzuki T, Kiyokawa H et al
  • Organizer: Abstract of the 11^<th> Japan-Taiwan Conference on Otolaryngology-Head and Neck Surgery: pp. 180
  • Place of Presentation: Kobe, Japan
• [Presentation] Assessment of pneumolabyrinth after middle ear trauma:our experience and meta-analysis (2011)
  • Author(s): Hidaka H, Miyazaki M, Kawase T, Kobayashi T
  • Organizer: Abstract of the 34th Meeting of the Association for Research in Otolaryngology: pp. 79
  • Place of Presentation: Baltimore, USA
• [Presentation] 迷路気腫(pneumolabyrinth)を伴った外傷性外リンパ瘻3症例の検討 (2010)
  • Author(s): 日高浩史
  • Organizer: 第20回日本耳科学会総会
  • Place of Presentation: 愛媛県松山市
  • Year and Date: 2010-10-08
• [Book] 【症例をどうみるか】扁桃周囲膿瘍が起点となり咀嚼筋間隙膿瘍へと進展した1症例.JOHNS29 (2013)
  • Author(s): 日高浩史,鈴木貴博,,石田英一,小林俊光
  • Publisher: 東京医学社
• [Book] 【症例をどうみるか】副咽頭間隙に進展し即時口蓋扁桃摘出による排膿を要した症例.JOHNS28 (2012)
  • Author(s): 館田勝,日高浩史,鈴木貴博,小林俊光
  • Publisher: 東京医学社
• [Book] 【頭頸部悪性腫瘍の初期症状とその対応】難聴・眩暈・耳痛.ENTONI128 (2011)
  • Author(s): 志賀清人,日高浩史
  • Publisher: 全日本病院出版会
• [Book] 【ER・ICUで知っておきたい外科手技と処置】その他の外科領域の処置耳鼻咽喉科領域の救急処置.救急・集中治療23 (2011)
  • Author(s): 日高浩史,鈴木貴博,小林俊光
  • Publisher: 総合医学社
• [Book] 【ER・ICUで知っておきたい外科手技と処置】その他の外科領域の処置耳鼻咽喉科領域の救急処置.(分担執筆) (2011)
  • Author(s): 日高浩史, 鈴木貴博, 小林俊光
  • Publisher: 総合医学社