| Project/Area Number |
22591875
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Otorhinolaryngology
|
|---|
| Research Institution | The University of Tokyo |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
柿木 章伸 東京大学, 医学部附属病院, 講師 (60243820)
牛尾 宗貴 (牛尾 宗貫) 東京大学, 医学部附属病院, その他 (70361483)
室伏 利久 帝京大学, 医学部附属溝口病院, 教授 (30242176)
|
|---|
| Project Period (FY) |
2010 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
|---|
| Keywords | 耳科学 / 前庭 / 前庭誘発眼筋電位 / 耳石器 / 前庭誘発頚筋電位 |
|---|
| Research Abstract |
To clarify the origin of ocular vestibular evoked myogenic potential (oVEMP), we performed experiments trying to record oVEMPs from guinea pigs. By inserting an electrode through lower eyelids and contacting it near extraocular muscles, we could record negative potentials with the peak latency of 3 msec. The potential was reduced by destruction of inner ear of the contralateral side, and was abolished by destruction of inner ears of both sides, suggesting that the response was dependent on the inner ears of both sides. Furthermore, by recoding directly from extraocular muscles, we confirmed that the oVEMPs in guinea pigs are originated from both the inferior oblique muscles and the inferior rectus muscles.
|
