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Compensation for swallowing function due to the impairment of the laryngeal elevator muscles

Research Project

Project/Area Number 22591913
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Otorhinolaryngology
Research InstitutionKyoto Prefectural University of Medicine

Principal Investigator

BANBA Hitoshi  京都府立医科大学, 医学(系)研究科(研究院), 客員講師 (30360035)

Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Keywords耳鼻咽喉科学 / 咽頭科学 / 嚥下 / 解剖学 / 臨床 / 神経科学 / 細胞・組織
Research Abstract

Laryngeal elevation surgery could be performed for patients with swallowing impairment responsible for reduced laryngeal elevation during swallowing. However, it is still uncertain whether this procedure would become a reasonable treatment for each patient. We therefore have investigated the neuronal mechanism that regulates the laryngeal elevator muscles and the alteration of the neural network due to partially deterioration of the laryngeal elevator muscles using mice. We have tried to reveal the effectiveness of the laryngeal elevation surgery for patients with injured laryngeal elevator muscles in in vivo mouse model.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (1 results)

All 2010

All Journal Article (1 results) (of which Peer Reviewed: 1 results)

  • [Journal Article] Synergistic effect between proteasome and autophagosome in the clearance of polyubiquitinated TDP-432010

    • Author(s)
      Urushitani M
    • Journal Title

      J Neurosci Res

      Volume: 88 Pages: 784-797

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed

URL: 

Published: 2010-08-23   Modified: 2019-07-29  

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