| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Research Abstract |
We have done the screening for the glaucoma genes using the single nucleotide polymorphisms (SNPs). Using association study, we identified the glaucoma susceptibility genes for primary open angle glaucoma, normal tension glaucoma, and exfoliation glaucoma. We also detect the rare amino acid substitutions in glutamate transporter gene GLAST by candidate gene approach. By the association study using SNPs and candidate gene approach, we detected glaucoma susceptibility genes.
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