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Involvement of Apelin/APJ system in intraocular neovascularizatio

Research Project

Project/Area Number 22591942
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Ophthalmology
Research InstitutionOsaka University

Principal Investigator

GOMI Fumi  大阪大学, 医学系研究科, 招へい教員 (80335364)

Co-Investigator(Kenkyū-buntansha) OSHIMA Yusuke  大阪大学, 医学系研究科, 講師 (20362717)
SUZUKI Mihoko  大阪大学, 医学部附属病院, 医員 (40611166)
IKUNO Yasushi  大阪大学, 医学系研究科, 講師 (50294096)
SAWA Miki  大阪大学, 医学系研究科, 助教 (50403043)
BABA Akemichii  大阪大学, 薬学部, 教授 (70107100)
KASAI Atushi  摂南大学, 薬学部, 助教 (40454649)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywordsアペリン / 血管新生 / 網膜 / 脈絡膜
Research Abstract

Apelin induces the hypoxia-induced retinal angiogenesisindependent of the VEGF/VEGF receptor 2 signaling pathway. Apelin is also involved in the development of choroidal neovascularization. Therefore, a therapy targeting of apelin possibly rescues nonresponders for anti-VEGF treatment.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (64 results)

All 2013 2012 2011 2010 Other

All Journal Article (28 results) (of which Peer Reviewed: 28 results) Presentation (34 results) Book (2 results)

  • [Journal Article] Transcriptional Regulation of VEGFA by the Endoplasmic Reticulum Stress Transducer OASIS in ARPE-19 Cells.2013

    • Author(s)
      Miyagi H, Kanemoto S, Saito A, Asada R, Iwamoto H, Izumi S, Kido M, Gomi F, Nishida K, Kiuchi Y, Imaizumi K.
    • Journal Title

      PLOS ONE

      Volume: 8 Issue: 1 Pages: 55155-55155

    • DOI

      10.1371/journal.pone.0055155

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Intravitreal bevacizumab for exudative branching vascular networks in polypoidal choroidal vasculopathy2012

    • Author(s)
      Wakabayashi T, Gomi F, Sawa M, Tsujikawa M, Nishida K
    • Journal Title

      Br J Ophthalmol

      Volume: 96 Issue: 3 Pages: 394-9

    • DOI

      10.1136/bjo.2011.204123

    • Related Report
      2012 Annual Research Report 2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Correlation of indocyanine green angiography and optical coherence tomography findings after intravitreal ranibizumab for polypoidal choroidal vasculopathy2012

    • Author(s)
      Ueno C, Gomi F, Sawa M, Nishida K.
    • Journal Title

      Retina

      Volume: 32 Issue: 10 Pages: 2006-13

    • DOI

      10.1097/iae.0b013e31825c1c31

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] omparison of different treatment intervals between bevacizumab injection and photodynamic therapy in combined therapy for age-related macular degeneration2012

    • Author(s)
      Sawa M, Iwata E, Ishikawa K, Gomi F,Nishida K, Terasaki H
    • Journal Title

      Jpn J Ophthalmol.

      Volume: 56 Pages: 470-5

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effectiveness of topical levofloxacin against conjunctival flora in intravitreal injection2012

    • Author(s)
      Ikuno Y, Sawa M, Tsujikawa M, Gomi F,Maeda N, Nishida K
    • Journal Title

      Jpn J Ophthalmol.

      Volume: 56 Issue: 5 Pages: 497-501

    • DOI

      10.1007/s10384-012-0160-5

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Reduced-fluence photodynamic therapy for subfoveal serous pigment epithelial detachment with choroidal vascular hyperpermeability2012

    • Author(s)
      Goto S, Gomi F, Ueno C, Nishida K.
    • Journal Title

      Am J Ophthalmol.

      Volume: 154 Pages: 865-871

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Choroidal observations in Vogt-Koyanagi-Harada disease using high-penetration optical coherence tomography.2012

    • Author(s)
      Nakai K, Gomi F, Ikuno Y, Yasuno Y, Nouchi T, Ohguro N, Nishida K
    • Journal Title

      Graefes Arch Clin Exp Ophthalmol.

      Volume: 250 Issue: 7 Pages: 1089-95

    • DOI

      10.1007/s00417-011-1910-7

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Foveal sparing in patients with Japanese Stargardt's disease and good visual acuity2012

    • Author(s)
      Nakao T, Tsujikawa M, Sawa M, Gomi F, Nishida K
    • Journal Title

      Jpn J Ophthalmol.

      Volume: 56 Issue: 6 Pages: 584-8

    • DOI

      10.1007/s10384-012-0172-1

    • NAID

      10031126906

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Usefulness of indocyanine green angiography to depict the distant retinal vascular anomalies associated with branch retinal vein occlusion causing serous macular detachment.2012

    • Author(s)
      Ueda T, Gomi F, Suzuki M, Sakaguchi H, Sawa M, Kamei M, Nishida K
    • Journal Title

      Retina

      Volume: 32 Issue: 2 Pages: 308-13

    • DOI

      10.1097/iae.0b013e31821c40a9

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Different dosing of intravitreal bevacizumab for choroidalneovascularization because of pathologic myopia2012

    • Author(s)
      Wakabayashi T, Ikuno Y, Gomi F.
    • Journal Title

      Retina.

      Volume: 37 Issue: 5 Pages: 880-6

    • DOI

      10.1097/iae.0b013e3181f2a293

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Topical bromfenac as an adjunctive treatment with intravitreal ranibizumab for exudative age-related macular degeneration.2012

    • Author(s)
      Gomi F, Sawa M, Tsujikawa M, Nishida K
    • Journal Title

      Retina

      Volume: 32 Pages: 1804-10

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Reduced-fluence photodynamic therapy for subfoveal serous pigment epithelial detachment with choroidal vascular hyperpermeability.2012

    • Author(s)
      Goto S, Gomi F, Ueno C, Nishida K.
    • Journal Title

      Am J Ophthalmol

      Volume: 154 Issue: 5 Pages: 865-871

    • DOI

      10.1016/j.ajo.2012.05.001

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Sema3E-PlexinD1 signaling selectively suppresses disoriented angiogenes is in ischemic retinopathy in mice. The Journal of clinical investigation2011

    • Author(s)
      Fukushima Y, et al
    • Journal Title

      J Clin Inv

      Volume: 121 Issue: 5 Pages: 1974-1985

    • DOI

      10.1172/jci44900

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of cataract in evaluation of macular pigment optical density by a utofluorescence spectrometry2011

    • Author(s)
      Sasamoto Y, Gomi F, Sawa M, Sakaguchi H, Tsujikawa M, Nishida K
    • Journal Title

      Invest Ophthalmol Vis Sci

      Volume: 56 Issue: 2 Pages: 927-32

    • DOI

      10.1167/iovs.10-5664

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Disposable eyelid speculum designed for intravitreal injection2011

    • Author(s)
      Gomi F, Matsuda Y, Futamura H, Nishida K.
    • Journal Title

      Retina.

      Volume: 31 Issue: 9 Pages: 1972-3

    • DOI

      10.1097/iae.0b013e31822f570c

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of 1-year lutein supplementation on macular pigment optical density and visual function2011

    • Author(s)
      Sasamoto Y, Gomi F, Sawa M, Tsujikawa M, Nishida K.
    • Journal Title

      Graefes Arch Clin Exp Ophthalmol.

      Volume: 249 Issue: 12 Pages: 1847-54

    • DOI

      10.1007/s00417-011-1780-z

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Topical bromfenac as an adjunctive treatment with intravitreal ranibizumab for exudative age-related macular degeneration.2010

    • Author(s)
      Gomi F, Sawa M, Tsujikawa M, Nishida K.
    • Journal Title

      Retina.

      Volume: 32 Pages: 1804-10

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Apelin Is a Crucial Factor for Hypoxia-Induced Retinal Angiogenesis.2010

    • Author(s)
      Kasai A, Ishimaru Y, Kinjo T, Satooka T, Matsumoto N, Yoshioka Y, Yamamuro A, Gomi F, Shintani N, Baba A, Maeda S.
    • Journal Title

      Arterioscler Thromb Vasc Biol.

      Volume: 30 Issue: 11 Pages: 2182-7

    • DOI

      10.1161/atvbaha.110.209775

    • Related Report
      2012 Final Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Efficacy of intravitreal bevacizumab combined with photodynamic therapy for polypoidal choroidal vasculopathy.2010

    • Author(s)
      Gomi F, Sawa M, Wakabayashi T, Sasamoto Y, Suzuki M, Tsujikawa M.
    • Journal Title

      Am J Ophthalmol.

      Volume: 150 Issue: 1 Pages: 48-54

    • DOI

      10.1016/j.ajo.2010.02.008

    • Related Report
      2012 Final Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Correlation of fundus autofluorescence with photoreceptor morphology and functional changes in eyes with retinitis pigmentosa.2010

    • Author(s)
      Wakabayashi T, Sawa M, Gomi F, Tsujikawa M.
    • Journal Title

      Acta Ophthalmol.

      Volume: 88 Issue: 5

    • DOI

      10.1111/j.1755-3768.2010.01926.x

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Macular Pigment Optical Density in Central Serous Chorioretinopathy.2010

    • Author(s)
      Sasamoto Y, Gomi F, Sawa M, Tsujikawa M, Hamasaki T.
    • Journal Title

      Invest Ophthalmol Vis Sci.

      Volume: 51 Issue: 10 Pages: 5219-25

    • DOI

      10.1167/iovs.09-4881

    • Related Report
      2012 Final Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Bevacizumab treatment for choroidal neovascularization due to age-related macular degeneration in Japanese patients.2010

    • Author(s)
      Suzuki M, Gomi F, Sawa M, Tsujikawa M, Sakaguchi H.
    • Journal Title

      Jpn J Ophthalmol.

      Volume: 54 Issue: 2 Pages: 124-8

    • DOI

      10.1007/s10384-009-0775-3

    • NAID

      10027203715

    • Related Report
      2012 Final Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association between the efficacy of photodynamic therapy and indocyanine green angiography findings for central serous chorioretinopathy2010

    • Author(s)
      Inoue R, Sawa M, Tsujikawa M, Gomi F
    • Journal Title

      Am J Ophthalmol.

      Volume: 149 Issue: 3 Pages: 441-6

    • DOI

      10.1016/j.ajo.2009.10.011

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] wo-year visual results for older Asian women treated with photodynamic therapy or bevacizumab for myopic choroidal neovascularization2010

    • Author(s)
      Ikuno Y, Nagai Y, Matsuda S, Arisawa A, Sho K, Oshita T, Takahashi K, Uchihori Y, Gomi F.
    • Journal Title

      Am J Ophthalmol.

      Volume: 149 Issue: 1 Pages: 140-6

    • DOI

      10.1016/j.ajo.2009.08.008

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Two-year visual results for older Asian women treated with photodynamic therapy or bevacizumab for myopic choroidal neovascularization2010

    • Author(s)
      Yasushi Ikuno
    • Journal Title

      Am J Ophthalmol.

      Volume: 149 Pages: 140-6

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association between the efficacy of photodynamic therapy and indocyanine green angiography findings for central serous chorioretinopathy.2010

    • Author(s)
      Ryo Inoue
    • Journal Title

      Am J Ophthalmol.

      Volume: 149 Pages: 441-6

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Correlation of fundus autofluorescence with photoreceptor morphology and functional changes in eyes with retinitis pigmentosa.2010

    • Author(s)
      Taku Wakabayashi
    • Journal Title

      Acta Ophthalmol.

      Volume: 88

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Laser-Induced Choroidal Neovascularization in Mice Attenuated by Deficiency in the Apelin-APJ System

    • Author(s)
      Hara C, Kasai A, Gomi F, Satooka T, Sakimoto S, Nakai K, Yoshioka Y,Yamamuro A, Maeda S, Nishida K.
    • Journal Title

      Investigative Ophthalmology & Visual Science

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Presentation] Involvement of apelin/APJ system in laser-induced choroidalneovascularization2012

    • Author(s)
      C. Ueno, A. Kasai, F. Gomi, T. Satooka, K. Nakai, Y. Yoshioka, A. Yamamuro, S. Maeda.
    • Organizer
      ARVO (The association of research in vision and ophthalmology)
    • Place of Presentation
      Fort Lauderdale, Florida, USA
    • Related Report
      2012 Final Research Report
  • [Presentation] 脈絡膜新生血管発生におけるapelin/APJシグナルの関与2012

    • Author(s)
      上野千佳子、笠井淳司、五味文、里岡達哉、中井慶、吉岡靖啓、山室晶子、前田定秋、西田幸二
    • Organizer
      第116回日本眼科学会総会
    • Place of Presentation
      東京
    • Related Report
      2012 Annual Research Report
  • [Presentation] Involvement of apelin/APJ system in laser-induced choroidal neovascularization2012

    • Author(s)
      C. Ueno, A. Kasai, F. Gomi, T. Satooka, K. Nakai, Y. Yoshioka, A. Yamamuro, S. Maeda
    • Organizer
      The association of research in vision and ophthalmology 2012
    • Place of Presentation
      Fort Lauderdale, Florida, USA
    • Related Report
      2012 Annual Research Report
  • [Presentation] 網膜色素上皮剥離に対する光線力学療法の治療効果2011

    • Author(s)
      後藤聡、五味文、上野千佳子、西田幸二
    • Organizer
      第50回日本網膜硝子体学会
    • Place of Presentation
      東京
    • Year and Date
      2011-12-02
    • Related Report
      2011 Annual Research Report
  • [Presentation] 傾斜乳頭症候群における脈絡膜厚と脈絡膜血管径2011

    • Author(s)
      上野千佳子、五味文、中井慶、沢美喜、西田幸二
    • Organizer
      第50回日本網膜硝子体学会
    • Place of Presentation
      東京
    • Year and Date
      2011-12-02
    • Related Report
      2011 Annual Research Report
  • [Presentation] Comparison of Spectral-Domain and High-Penetration Optical Coherence Tomography in the Observation of the Retinal Changes in Age-Related Macular Degeneration2011

    • Author(s)
      Kaori Sayanagi, Fumi Gomi, Yoshiaki Yasuno
    • Organizer
      American Academy of Ophthalmology
    • Place of Presentation
      Orlando,アメリカ
    • Year and Date
      2011-10-24
    • Related Report
      2011 Annual Research Report
  • [Presentation] 加齢黄斑変性の深部病変の観察における高侵達光干渉断層計と従来機の比較2011

    • Author(s)
      佐柳香織、五味文、生野恭司、城友香里、秋葉正博、西田幸二
    • Organizer
      第65回日本臨床眼科学会
    • Place of Presentation
      東京
    • Year and Date
      2011-10-07
    • Related Report
      2011 Annual Research Report
  • [Presentation] 眼底自発蛍光と黄斑色素2011

    • Author(s)
      五味文
    • Organizer
      第47回日本眼光学会総会
    • Place of Presentation
      東京(招待講演)
    • Year and Date
      2011-09-03
    • Related Report
      2011 Annual Research Report
  • [Presentation] 眼科における光線力学療法2011

    • Author(s)
      五味文
    • Organizer
      第21回日本光線力学学会
    • Place of Presentation
      大阪(招待講演)
    • Year and Date
      2011-07-03
    • Related Report
      2011 Annual Research Report
  • [Presentation] 加齢黄斑変性に対するラニビズマブ治療におけるブロムフェナク点眼併用の有用性2011

    • Author(s)
      五味 文、沢 美喜、 辻川 元一、西田 幸二;
    • Organizer
      第115回日本眼科学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-04-18
    • Related Report
      2012 Final Research Report 2011 Annual Research Report
  • [Presentation] ポリープ状脈絡膜血管症(PCV)のラニビズマブ治療後のOCT所見2011

    • Author(s)
      上野千佳子, 五味文, 沢美喜, 辻川元一, 西田幸二
    • Organizer
      第115回日本眼科学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-04-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] 眼底自発蛍光2011

    • Author(s)
      五味文
    • Organizer
      第115回日本眼科学会総会
    • Place of Presentation
      名古屋(招待講演)
    • Year and Date
      2011-04-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] Efficacy of Intravitreal Ranibizumab in Eyes with a History of Intravitreal Bevacizumab Treatment for Age-Related Macular Degeneration.2011

    • Author(s)
      Ueno C, Gomi F , SawaM, ,Tsujikawa M, Nishida K.
    • Organizer
      第26回 APAO
    • Place of Presentation
      シドニー
    • Year and Date
      2011-03-24
    • Related Report
      2012 Final Research Report
  • [Presentation] Suppression of pathological retinal angiogenesis by siRNA targeting apelin2011

    • Author(s)
      笠井淳司
    • Organizer
      第84回日本薬理学会
    • Place of Presentation
      横浜
    • Year and Date
      2011-03-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] ポリープ状脈絡膜血管症(PCV)のラニビズマブ治療後の OCT所見.2011

    • Author(s)
      上野 千佳子, 五味 文, 沢 美喜, 辻川 元一, 西田 幸二
    • Organizer
      第115回日本眼科学会総会
    • Place of Presentation
      名古屋
    • Related Report
      2012 Final Research Report
  • [Presentation] 加齢黄斑変性患者における網膜色素上皮裂孔を生じた症例の視力ならびに眼底所見の変化2011

    • Author(s)
      浅尾和伸、五味 文、上野千佳子、鈴木三保子、沢美喜、辻川元一、西田幸二
    • Organizer
      第65回日本臨床眼科学会
    • Place of Presentation
      東京
    • Related Report
      2012 Final Research Report 2011 Annual Research Report
  • [Presentation] 加齢黄斑変性の深部病変の観察における高侵達光干渉断層計と従来機の比較.2011

    • Author(s)
      佐柳 香織、 五味 文、生野 恭司 、城 友香里、秋葉 正博、西田 幸二
    • Organizer
      第65回日本臨床眼科学会
    • Place of Presentation
      東京
    • Related Report
      2012 Final Research Report
  • [Presentation] 浸出型加齢黄斑変性に対するラニビズマブ硝子体内投与による治療反応2011

    • Author(s)
      鈴木 三保子、五味 文、沢 美喜、西田幸二
    • Organizer
      第65回日本臨床眼科学会
    • Place of Presentation
      東京
    • Related Report
      2012 Final Research Report 2011 Annual Research Report
  • [Presentation] 網膜色素線条に合併する脈絡膜新生血管にかかわる因子の検討.2011

    • Author(s)
      沢 美喜、五味 文、西田 幸二
    • Organizer
      第65回日本臨床眼科学会
    • Place of Presentation
      東京
    • Related Report
      2012 Final Research Report
  • [Presentation] Apelin is a crucial factor for hypoxia-induced retinal angiogenesis2010

    • Author(s)
      笠井淳司
    • Organizer
      第18回日本血管生物医学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2010-12-03
    • Related Report
      2010 Annual Research Report
  • [Presentation] 虚血性網膜血管新生におけるapelin/APJ systemの役割2010

    • Author(s)
      石丸侑希
    • Organizer
      第60回日本薬学会近畿支部総会・大会
    • Place of Presentation
      大阪
    • Year and Date
      2010-10-30
    • Related Report
      2010 Annual Research Report
  • [Presentation] 眼内血管新生性疾患におけるアペリンの病態生理学的役割と創薬標的分子としての可能性2010

    • Author(s)
      笠井淳司
    • Organizer
      第60回日本薬学会近畿支部総会・大会
    • Place of Presentation
      大阪
    • Year and Date
      2010-10-30
    • Related Report
      2010 Annual Research Report
  • [Presentation] Effect of 1-Year Lutein Supplementation on Macular Pigment Optical Density and Visual Function2010

    • Author(s)
      五味文
    • Organizer
      2010 American Academy of Ophthalmology
    • Place of Presentation
      シカゴ、アメリカ
    • Year and Date
      2010-10-18
    • Related Report
      2010 Annual Research Report
  • [Presentation] Management of polypoidal choroidal vasculopathy Anti-angiogenesis therapy for PCV2010

    • Author(s)
      五味文
    • Organizer
      第25回Asia Pacific Ophthalmology Conference
    • Place of Presentation
      北京、中国(招待講演)
    • Year and Date
      2010-09-18
    • Related Report
      2010 Annual Research Report
  • [Presentation] Apelin is a crucial factor for hypoxia-induced retinal angiogenesis2010

    • Author(s)
      笠井淳司
    • Organizer
      16th World Congress of Basic and Clinical Pharmacology, IUPHAR
    • Place of Presentation
      コペンハーゲン,デンマーク
    • Year and Date
      2010-07-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] Efficacy of Intravitreal Bevacizumab Combined with Photodynamic Therapy for Polypoidal Choroidal Vasculopathy2010

    • Author(s)
      五味文
    • Organizer
      World Ophthalmic Conference
    • Place of Presentation
      ベルリン、ドイツ
    • Year and Date
      2010-06-07
    • Related Report
      2010 Annual Research Report
  • [Presentation] 抗VEGF療法の長期管理2010

    • Author(s)
      五味文
    • Organizer
      第114回日本眼科学会総会
    • Place of Presentation
      名古屋(招待講演)
    • Year and Date
      2010-04-16
    • Related Report
      2010 Annual Research Report
  • [Presentation] スペクトラルドメイン光干渉断層計によるranibizumab投与後の加齢黄斑変性病巣の観察2010

    • Author(s)
      鈴木三保子
    • Organizer
      第114回日本眼科学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2010-04-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] 抗血管新生療法2010

    • Author(s)
      五味 文
    • Organizer
      第33回日本眼科手術学会教育セミナー
    • Place of Presentation
      東京
    • Related Report
      2012 Final Research Report
  • [Presentation] 抗 VEGF 療法の長期管理2010

    • Author(s)
      五味 文
    • Organizer
      第114回日本眼科学会総会
    • Place of Presentation
      名古屋
    • Related Report
      2012 Final Research Report
  • [Presentation] スペクトラルドメイン光干渉断層計による ranibizumab 投与後の加齢黄斑変性病巣の観察2010

    • Author(s)
      鈴木三保子、五味 文
    • Organizer
      第114回日本眼科学会総会
    • Place of Presentation
      名古屋
    • Related Report
      2012 Final Research Report
  • [Presentation] 抗 VEGF 療法の 1 年間の施行回数に影響を与える spectral-domain OCT所見.2010

    • Author(s)
      佐柳 香織、 五味 文、沢 美喜、坂口 裕和、辻川 元一
    • Organizer
      第114回日本眼科学会総会
    • Place of Presentation
      名古屋
    • Related Report
      2012 Final Research Report
  • [Presentation] Efficacy of Intravitreal Bevacizumab Combined with Photodynamic Therapy for Polypoidal Choroidal Vasculopathy .2010

    • Author(s)
      Fumi Gomi, Miki Sawa, Taku Wakabayashi, Yuzuru Sasamoto, Mihoko Suzuki, Motokazu Tsujikawa
    • Organizer
      WOC
    • Place of Presentation
      Berlin
    • Related Report
      2012 Final Research Report
  • [Presentation] 脈絡膜 新生 血管発 生にお けるpelin/APJ シグナルの関与

    • Author(s)
      上野千佳子、 笠井淳司、 五味文、里岡達哉、中井慶、吉岡靖啓、山室晶子、前田定秋、西田 幸二
    • Organizer
      第116回日本眼科学会総会
    • Place of Presentation
      東京
    • Related Report
      2012 Final Research Report
  • [Book] これだけは知っておきたいポイント加齢黄斑変性2010

    • Author(s)
      大路 正人、五味 文
    • Publisher
      医薬ジャーナル
    • Related Report
      2012 Final Research Report
  • [Book] 加齢黄斑変性、これだけは知っておきたいポイント2010

    • Author(s)
      五味文, 他
    • Total Pages
      69
    • Publisher
      医薬ジャーナル
    • Related Report
      2010 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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