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Pathogenesisof Coats disease: establishing a concept of pediatric retinal detachment

Research Project

Project/Area Number 22591956
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Ophthalmology
Research InstitutionUniversity of Occupational and Environmental Health, Japan

Principal Investigator

KONDO Hiroyuki  産業医科大学, 医学部, 准教授 (40268991)

Co-Investigator(Kenkyū-buntansha) TAHIRA Tomoko  九州大学, 生体防御医学研究所, 講師 (50155230)
UTIO Eiichi  福岡大学, 医学部, 教授 (70232840)
Co-Investigator(Renkei-kenkyūsha) HAYASHI Kenshi  九州大学, 生体防御医学研究所, 特任教授 (00019671)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
KeywordsCoats病 / 家族性滲出性硝子体網膜症 / NDP遺伝子 / 血管内皮増殖因子 / VEGF / 網膜剥離 / 小児 / WNTシグナル / 遺伝子 / 網膜 / 未熟児網膜症 / 血管内皮成長因子 / Norrie病 / TSPAN12
Research Abstract

Coats disease is a non-hereditary ocular disorder that affects children’s eyes. It is characterized by extensive serous retinal detachment. The retinal findings are similar to those of familial exudative vitreoretinopathy, a hereditary disease. Because Coats disease mainly affects male patients, the pathogenesis is speculated but not established for the involvement of the gene for Norrie disease, a gene for X-linked familial exudative vitreoretinopathy. Moreover, expression of vascular endothelial growth factor is increased in Coats disease, however, the detail of the expression level remains unclear. We collected intraocular fluid samples and the cellular components during vitreous surgery, and searched for alternations of the DNA and protein in order to unveil the pathophysiology of the disease.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (78 results)

All 2013 2012 2011 2010 Other

All Journal Article (31 results) (of which Peer Reviewed: 28 results) Presentation (38 results) (of which Invited: 4 results) Book (9 results)

  • [Journal Article] Genetic variants of FZD4 and LRP5 genes in patients with advanced retinopathy of prematurity2013

    • Author(s)
      Kondo H
    • Journal Title

      Mol Vis

      Volume: (19) Pages: 476-485

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Identification of causative pathogens in eyes with bacterial conjunctivitis by bacterial cell count and microbiota analysis2013

    • Author(s)
      Aoki R, Kondo H
    • Journal Title

      Ophthalmology

      Volume: (120) Pages: 668-676

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Genetic variants of FZD4 and LRP5 genes in patients with advanced retinopathy of prematurity2013

    • Author(s)
      Kondo H (6名中筆頭)
    • Journal Title

      Molecular Vision

      Volume: 19 Pages: 476-485

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Identification of causative pathogens in eyes with bacterial conjunctivitis by bacterial cell count and microbiota analysis2013

    • Author(s)
      Aoki R, Kondo H (7名中5番目)
    • Journal Title

      Ophthalmology

      Volume: 120 Issue: 4 Pages: 668-676

    • DOI

      10.1016/j.ophtha.2012.10.001

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] National survey of microphthalmia in Japan2012

    • Author(s)
      Nishina S, Kurosaka D, Nishida Y. Kondo H, et al. et al
    • Journal Title

      Jpn J Ophthalmol

      Volume: (56) Pages: 198-202

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Novel compound heterozygous mutations in MFRP gene in Japanese patient with posterior microphthalmos2012

    • Author(s)
      Matsushita I, Kondo H, et al
    • Journal Title

      Jpn J Ophthalmol

      Volume: (56) Pages: 396-400

    • NAID

      10030952220

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 黄斑剥離を伴う裂孔原性網膜剥離に対する硝子体術後の変視量の検討2012

    • Author(s)
      森田啓文、近藤寛之
    • Journal Title

      眼科手術

      Volume: (26) Pages: 449-452

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] ベバシズマブ硝子体内投与併用網膜光凝固術が奏効した重症未熟児網膜症の3例2012

    • Author(s)
      藤田陽子、近藤寛之
    • Journal Title

      眼臨紀

      Volume: (5) Pages: 377-381

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 小眼球症に伴う眼窩発育異常の画像評価2012

    • Author(s)
      仁科幸子、近藤寛之
    • Journal Title

      眼臨紀

      Volume: (5) Pages: 387-391

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Novel compound heterozygous mutations in the MFRP gene in a Japanese patient with posterior microphthalmos2012

    • Author(s)
      Matsushita I, Kondo H (3名中2番目)
    • Journal Title

      Japanese Journal of Ophthalmology

      Volume: 56 Issue: 4 Pages: 396-400

    • DOI

      10.1007/s10384-012-0145-4

    • NAID

      10030952220

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Survey of microphthalmia in Japan.2012

    • Author(s)
      Nishina S, Kurosaka D, Nishida Y, Kondo H, Kobayashi Y, Azuma N.
    • Journal Title

      Jpn J Ophthalmol

      Volume: 56 Issue: 3 Pages: 198-202

    • DOI

      10.1007/s10384-012-0126-7

    • NAID

      10030626740

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ベバシズマブ硝子体内投与併用網膜光凝固術が奏効した重症未熟児網膜症の3例2012

    • Author(s)
      藤田陽子、近藤寛之(8名中7番目)
    • Journal Title

      眼臨紀

      Volume: 5 Pages: 377-381

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 小眼球症に伴う眼窩発育異常の画像評価2012

    • Author(s)
      仁科幸子、近藤寛之(6名中5番目)
    • Journal Title

      眼臨紀

      Volume: 5 Pages: 387-391

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 黄斑剥離を伴う裂孔原性網膜剥離に対する硝子体術後の変視量の検討2012

    • Author(s)
      森田啓文、近藤寛之(3名中2番目)
    • Journal Title

      眼科手術

      Volume: 25 Pages: 449-452

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] National survey of microphthalmia in Japan2012

    • Author(s)
      Nishina S, Kurosaka D, Nishida Y.Kondo H, et al
    • Journal Title

      Jpn J Ophthalmol

      Volume: (In press)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 未熟児網膜症に対する抗VEGF療法の効果の検討2012

    • Author(s)
      渡辺晃久、近藤寛之, 他
    • Journal Title

      眼科手術

      Volume: 25 Pages: 115-119

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Quercetin induces the expression of peroxiredoxins 3 and 5 via the Nrf2/NRF1 transcription pathway2011

    • Author(s)
      Miyamoto N, Izumi H, Miyamoto R, Kondo H, et al
    • Journal Title

      Invest Ophthalmol Vis Sci

      Volume: (52) Pages: 1055-1063

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Transcriptional regulation of activating transcription factor 4 (ATF4) under oxidative stress in retinal pigment epithelial ARPE-19 cells2011

    • Author(s)
      Miyamoto N, Izumi H, Miyamoto R, Bin H, Kondo H, et al
    • Journal Title

      Invest Ophthalmol Vis Sci

      Volume: (52) Pages: 1226-34

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Mutations in TSPAN12 gene in Japanese patients with familial exudative vitreoretinopathy2011

    • Author(s)
      Kondo H, Kusaka S, Yoshinaga A, Uchio E, Tahira T
    • Journal Title

      Am J Ophthalmol

      Volume: (151) Pages: 1095-1100

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 家族性滲出性硝子体網膜症(特集・遺伝性網膜・黄斑ジストロフィアップデート)2011

    • Author(s)
      近藤寛之
    • Journal Title

      あたらしい眼科

      Volume: (28) Pages: 963-968

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
  • [Journal Article] 重症未熟児網膜症に対しベバシズマブ硝子体内投与を行った症例の検討2011

    • Author(s)
      有田直子、林英之、内尾英一、近藤寛之
    • Journal Title

      臨床眼科

      Volume: (65) Pages: 1225-1229

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 未熟児網膜症に対する抗VEGF療法の効果の検討v2011

    • Author(s)
      渡辺晃久、近藤寛之他
    • Journal Title

      眼科手術

      Volume: (25) Pages: 115-119

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Mutations in TSPAN12 gene in Japanese patients with familial exudative vitreoretinopathy2011

    • Author(s)
      Kondo H, Kusaka S, Yoshinaga A, et al
    • Journal Title

      Am J Ophthalmol

      Volume: 151 Issue: 6 Pages: 1095-1100

    • DOI

      10.1016/j.ajo.2010.11.026

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Quercetin induces the expression of peroxiredoxins 3 and 5 via the Nrf2/NRF1 transcription pathway2011

    • Author(s)
      Miyamoto N, Izumi H, Miyamoto R, Kondo H, et al.
    • Journal Title

      Invest Ophthalmol Vis Sci

      Volume: 52 Pages: 1055-1063

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mutations in TSPAN12 gene in Japanese patients with familial exudative vitreoretinopathy2011

    • Author(s)
      Kondo H, Kusaka S, Yoshinaga A, et al.
    • Journal Title

      Am J Ophthalmol

      Volume: Epub ahead of print

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A case of Fukuyama congenital muscular dystrophy associated with negative electroretinograms2010

    • Author(s)
      Kondo H, Saito K, Urano M, et al
    • Journal Title

      Jpn J Ophthalmol

      Volume: (54) Pages: 662-624

    • NAID

      10027666559

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 成人と小児における増殖硝子体網膜症の手術成績2010

    • Author(s)
      小山田剛、近藤寛之、林英之、内尾英一
    • Journal Title

      臨眼

      Volume: (64) Pages: 543-546

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 眼科(4)色覚異常、(9)網膜色素変性、(12)網膜剥離. 臨床病理レビュー2010

    • Author(s)
      近藤寛之
    • Journal Title

      特集病気をもちながらどこまで働けるか―疾病と就労の臨床診断―

      Volume: (146) 214

    • Related Report
      2012 Final Research Report
  • [Journal Article] A case of Fukuyama congenital muscular dystrophy associated with negative electroretinograms2010

    • Author(s)
      Kondo H, Saito K, Urano M, et al.
    • Journal Title

      Jpn J Ophthalmol

      Volume: 54 Pages: 622-624

    • NAID

      10027666559

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 成人と小児における増殖硝子体網膜症の手術成績2010

    • Author(s)
      小山田剛、近藤寛之、林英之、内尾英一
    • Journal Title

      臨床眼科

      Volume: 64 Pages: 543-546

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 眼科(4)色覚異常、(9)網膜色素変性、(12)網膜剥離2010

    • Author(s)
      近藤寛之
    • Journal Title

      臨床病理レビュー、特集病気をもちながらどこまで働けるか-疾病と就労の臨床診断-

      Volume: 146

    • Related Report
      2010 Annual Research Report
  • [Presentation] 剥離の診断と治療、その進歩2013

    • Author(s)
      近藤寛之
    • Organizer
      網膜第151回宮崎県眼科医会講習会(招待講演)
    • Place of Presentation
      宮崎市(ホテルスカイタワー)
    • Year and Date
      2013-02-02
    • Related Report
      2012 Final Research Report
  • [Presentation] Genetic variations of FDZ4 and LRP5 genes in eyes with advanced retinopathy of prematurity2012

    • Author(s)
      Kondo H (6名中筆頭)
    • Organizer
      第51回日本網膜硝子体学会
    • Place of Presentation
      甲府市(富士屋ホテル)
    • Year and Date
      2012-11-30
    • Related Report
      2012 Final Research Report
  • [Presentation] Genetic variations in advanced retinopathy of prematurity2012

    • Author(s)
      Kondo H
    • Organizer
      World ROP congress III
    • Place of Presentation
      Intercontinental Shanghai Puxi, Shanghai, China
    • Year and Date
      2012-10-16
    • Related Report
      2012 Final Research Report
  • [Presentation] A case of atypical retinopathy of prematurity2012

    • Author(s)
      Kondo H
    • Organizer
      5th Association of Pediatric Retinal Surgeons Meeting
    • Place of Presentation
      Hotel Park City, Park city, Uta, USA
    • Year and Date
      2012-09-21
    • Related Report
      2012 Final Research Report
  • [Presentation] New mutation in GJA8 gene is associated with unique phenotype of familial microphthalmia with anomalies of iris and lens2012

    • Author(s)
      Kondo H(5名中筆頭)
    • Organizer
      Annual meeting of the Association for Research in Vision and Ophthalmology
    • Place of Presentation
      Fort Lauderdale, Florida, USA
    • Year and Date
      2012-05-07
    • Related Report
      2012 Annual Research Report 2012 Final Research Report
  • [Presentation] VEGF levels in refractory Coats disease with or without intravitreal bevacizumab2012

    • Author(s)
      Kondo H
    • Organizer
      2nd Pediatric Retinal Vascular Disease Forum
    • Place of Presentation
      Grand Hyatt on Union Square, San Francisco
    • Year and Date
      2012-02-11
    • Related Report
      2011 Annual Research Report
  • [Presentation] Autosomal recessive familial exudative vitreoretinopathy2012

    • Author(s)
      Kondo H
    • Organizer
      2nd Pediatric Retinal Vascular Disease Forum
    • Place of Presentation
      Grand Hyatt on Union Square, San Francisco
    • Year and Date
      2012-02-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] 教育セミナー20未熟児網膜症の診断と治療硝子体手術2012

    • Author(s)
      近藤寛之
    • Organizer
      第35回日本眼科手術学会総会
    • Place of Presentation
      名古屋国際会議場(名古屋)(招待講演)
    • Year and Date
      2012-01-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] A case of atypical retinopathy of prematurity2012

    • Author(s)
      Kondo H (単著)
    • Organizer
      Association of Pediatric Retinal Surgeons Meeting
    • Place of Presentation
      Hotel Park City, Park city, Uta, USA
    • Related Report
      2012 Annual Research Report
  • [Presentation] bevacizumabを用いた未熟児網膜症の治療(インストラクションコース26)2011

    • Author(s)
      近藤寛之, 他
    • Organizer
      第65回日本臨床眼科学会
    • Place of Presentation
      東京国際フォーラム(東京)
    • Year and Date
      2011-10-08
    • Related Report
      2011 Annual Research Report
  • [Presentation] 眼科診療に必要な遺伝性網膜硝子体疾患-診療スタンダード2011-(インストラクションコース7)2011

    • Author(s)
      近藤寛之, 他
    • Organizer
      第65回日本臨床眼科学会
    • Place of Presentation
      東京国際フォーラム(東京)
    • Year and Date
      2011-10-07
    • Related Report
      2011 Annual Research Report
  • [Presentation] X連鎖性網膜分離症にみられたRSI遺伝子異常と臨床像2011

    • Author(s)
      近藤寛之, 他
    • Organizer
      第115回日本眼科学会総会
    • Place of Presentation
      東京国際フォーラム(東京)
    • Year and Date
      2011-05-13
    • Related Report
      2011 Annual Research Report
  • [Presentation] Search for SOX17 gene mutations in patients with familial exudative vitreoretinopathy2011

    • Author(s)
      Kondo H, Tawara A, et al
    • Organizer
      Annual meeting of the Association for Research in Vision and Ophthalmology
    • Place of Presentation
      Fort Lauderdale, Florida, USA
    • Year and Date
      2011-05-11
    • Related Report
      2012 Final Research Report
  • [Presentation] Search for SOX17 Gene Mutations In Patients With Familial Exudative Vitreoretinopathy2011

    • Author(s)
      Kondo H, Tawara A, et al
    • Organizer
      Annual meeting of the Association for Research in Vision and Ophthalmology
    • Place of Presentation
      Fort Lauderdale, Florida
    • Year and Date
      2011-05-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] VEGF levels in refractory Coats disease with or without intravitreal bevacizumab2011

    • Author(s)
      Kondo H
    • Organizer
      2nd Pediatric Retinal Vascular Disease Forum
    • Place of Presentation
      Grand Hyatt on Union Square, San Francisco, USA
    • Year and Date
      2011-02-11
    • Related Report
      2012 Final Research Report
  • [Presentation] Autosomal recessive familial exudative vitreoretinopathy2011

    • Author(s)
      Kondo H
    • Organizer
      2nd Pediatric Retinal Vascular Disease Forum
    • Place of Presentation
      Grand Hyatt on Union Square, San Francisco, USA
    • Year and Date
      2011-02-10
    • Related Report
      2012 Final Research Report
  • [Presentation] TSPAN12遺伝子異常による家族性滲出性硝子体網膜症2010

    • Author(s)
      近藤寛之、他
    • Organizer
      第64回日本臨床眼科学会
    • Place of Presentation
      神戸市(ポートピアホテル)
    • Year and Date
      2010-11-12
    • Related Report
      2012 Final Research Report
  • [Presentation] TSPAN12遺伝子異常による家族性滲出性硝子体網膜症2010

    • Author(s)
      近藤寛之, 他
    • Organizer
      第64回日本臨床眼科学会
    • Place of Presentation
      神戸(ポートピアホテル)
    • Year and Date
      2010-11-12
    • Related Report
      2010 Annual Research Report
  • [Presentation] 遺伝性網膜疾患のトピックス~遺伝性網膜硝子体症~2010

    • Author(s)
      近藤寛之
    • Organizer
      第85回網膜病変談話会
    • Place of Presentation
      東京都(興和大ホール)
    • Year and Date
      2010-11-04
    • Related Report
      2012 Final Research Report
  • [Presentation] 遺伝性網膜疾患のトピックス~遺伝性網膜硝子体症~2010

    • Author(s)
      近藤寛之
    • Organizer
      第85回網膜病変談話会
    • Place of Presentation
      東京(興和大ホール)
    • Year and Date
      2010-11-04
    • Related Report
      2010 Annual Research Report
  • [Presentation] 重症Coats病にみられた眼内VEGF濃度勾配とbevacizumab硝子体投与の効果2010

    • Author(s)
      近藤寛之 (4名中筆頭)
    • Organizer
      第66回日本臨床眼科学会
    • Place of Presentation
      京都国際会議場、京都市
    • Year and Date
      2010-10-25
    • Related Report
      2012 Final Research Report
  • [Presentation] 小児の網膜剥離は遺伝性か?2010

    • Author(s)
      近藤寛之
    • Organizer
      第111回佐賀大学眼科臨床懇話会
    • Place of Presentation
      佐賀市(ホテルマリターレ創世佐賀)
    • Year and Date
      2010-10-16
    • Related Report
      2012 Final Research Report
  • [Presentation] 小児の網膜剥離は遺伝性か?2010

    • Author(s)
      近藤寛之
    • Organizer
      第111回佐賀大学眼科臨床懇話会
    • Place of Presentation
      佐賀(ホテルマリターレ創世佐賀)
    • Year and Date
      2010-10-16
    • Related Report
      2010 Annual Research Report
  • [Presentation] bevacizumabを用いた未熟児網膜症の治療(インストラクションコース26)2010

    • Author(s)
      近藤寛之他
    • Organizer
      第65回日本臨床眼科学会
    • Place of Presentation
      東京都(東京国際フォーラム)
    • Year and Date
      2010-10-08
    • Related Report
      2012 Final Research Report
  • [Presentation] 網膜剥離の診かた、治療の考え方2010

    • Author(s)
      近藤寛之
    • Organizer
      第48回六大学合同眼科研究会
    • Place of Presentation
      福岡市(九州大学百年講堂)
    • Year and Date
      2010-09-04
    • Related Report
      2012 Final Research Report
  • [Presentation] 網膜剥離の診かた、治療の考え方2010

    • Author(s)
      近藤寛之
    • Organizer
      第48回六大学合同眼科研究会
    • Place of Presentation
      隔岡(九州大学百年講堂)
    • Year and Date
      2010-09-04
    • Related Report
      2010 Annual Research Report
  • [Presentation] わが国のStickler症候群にみられたCOL2A1遺伝子異常とその臨床像2010

    • Author(s)
      近藤寛之、他
    • Organizer
      第114回日本眼科学会総会
    • Place of Presentation
      名古屋市(国際会議場)
    • Year and Date
      2010-04-16
    • Related Report
      2012 Final Research Report
  • [Presentation] わが国のStickler症候群にみられたCOL2A1遺伝子異常とその臨床像2010

    • Author(s)
      近藤寛之, 他
    • Organizer
      第114回日本眼科学会総会
    • Place of Presentation
      名古屋(国際会議場)
    • Year and Date
      2010-04-16
    • Related Report
      2010 Annual Research Report
  • [Presentation] Genetic variations in advanced retinopathy of prematurity

    • Author(s)
      Kondo H (単著)
    • Organizer
      Association of Pediatric Retinal Surgeons Meeting
    • Place of Presentation
      Hotel Park City, Park city
    • Related Report
      2012 Annual Research Report
  • [Presentation] Genetic variations in advanced retinopathy of prematurity

    • Author(s)
      Kondo H (単著)
    • Organizer
      World ROP congress III
    • Place of Presentation
      Intercontinental Shanghai Puxi, Shanghai, China
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Genetic variations of FDZ4 and LRP5 genes in eyes with advanced retinopathy of prematurity

    • Author(s)
      Kondo H (6名中筆頭)
    • Organizer
      第51回日本網膜硝子体学会
    • Place of Presentation
      富士屋ホテル, 甲府市, 日本
    • Related Report
      2012 Annual Research Report
  • [Presentation] 未熟児網膜症最新の治療戦略

    • Author(s)
      近藤寛之 (単著)
    • Organizer
      第60回九州新生児研究会
    • Place of Presentation
      ホテルクラウンパレス北九州、北九州市、日本
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 重症Coats病にみられた眼内VEGF濃度勾配とbevacizumab硝子体投与の効果

    • Author(s)
      近藤寛之 (4名中筆頭)
    • Organizer
      第65回日本臨床眼科学会
    • Place of Presentation
      京都国際会議場、京都市、日本
    • Related Report
      2012 Annual Research Report
  • [Presentation] 小瞳孔・白内障を伴う家族性小眼球症の原因遺伝子のエクソーム解析による同定

    • Author(s)
      近藤寛之 (6名中筆頭)
    • Organizer
      第116回日本眼科学会総会
    • Place of Presentation
      東京国際フォーラム、東京都、日本
    • Related Report
      2012 Annual Research Report
  • [Presentation] 真性小眼球におけるMFRP遺伝子の関与

    • Author(s)
      松下五佳・近藤寛之(7名中2番目)
    • Organizer
      第116回日本眼科学会総会
    • Place of Presentation
      東京国際フォーラム、東京都、日本
    • Related Report
      2012 Annual Research Report
  • [Presentation] Stickler症候群など全身疾患に伴う裂孔原性網膜剥離(シンポジウム9 小児の網膜硝子体疾患)

    • Author(s)
      近藤寛之 (単著)
    • Organizer
      第36回日本眼科手術学会総会
    • Place of Presentation
      福岡国際会議場、福岡市、日本
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 網膜剥離の診断と治療、その進歩

    • Author(s)
      近藤寛之 (単著)
    • Organizer
      第151回宮崎県眼科医会講習会
    • Place of Presentation
      ホテルスカイタワー、宮崎市、日本
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 先天小瞳孔の遺伝子解析

    • Author(s)
      近藤寛之 (7名中筆頭)
    • Organizer
      第117回日本眼科学会総会
    • Place of Presentation
      東京国際フォーラム、東京都、日本
    • Related Report
      2012 Annual Research Report
  • [Book] 臨床糖尿病マニュアル改訂第3版2012

    • Author(s)
      近藤寛之
    • Total Pages
      482
    • Publisher
      南江堂
    • Related Report
      2012 Final Research Report
  • [Book] 臨床糖尿病マニュアル改訂第3版2012

    • Author(s)
      近藤寛之
    • Publisher
      南江堂
    • Related Report
      2012 Annual Research Report
  • [Book] 眼科手術学:網膜・硝子体II2012

    • Author(s)
      近藤寛之
    • Publisher
      文光堂
    • Related Report
      2012 Annual Research Report
  • [Book] 専門医のための眼科臨床クオリファイ2012

    • Author(s)
      近藤寛之
    • Total Pages
      8
    • Publisher
      中山書店
    • Related Report
      2011 Annual Research Report
  • [Book] Eye Surgery Now 6 きれいな小児眼科手術 これであなたも悩まない!2011

    • Author(s)
      近藤寛之
    • Total Pages
      153
    • Publisher
      メジカルビュー社
    • Related Report
      2012 Final Research Report
  • [Book] 専門医のための眼科臨床クオリファイ8網膜血管障害2011

    • Author(s)
      近藤寛之
    • Total Pages
      256
    • Publisher
      中山書店
    • Related Report
      2012 Final Research Report
  • [Book] 専門医のための眼科臨床クオリファイ9こどもの眼と疾患2011

    • Author(s)
      近藤寛之
    • Total Pages
      286
    • Publisher
      中山書店
    • Related Report
      2012 Final Research Report
  • [Book] Eye Surgery Now 6きれいな小児眼科手術これであなたも悩まない!2011

    • Author(s)
      近藤寛之
    • Total Pages
      6
    • Publisher
      メジカルビュー社
    • Related Report
      2011 Annual Research Report
  • [Book] 眼科手術学:網膜・硝子体II2010

    • Author(s)
      近藤寛之
    • Total Pages
      336
    • Publisher
      文光堂
    • Related Report
      2012 Final Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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