• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Corneal stiffness sensing using high speed camera

Research Project

Project/Area Number 22591965
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Ophthalmology
Research InstitutionHiroshima University

Principal Investigator

KIUCHI Yoshiaki  広島大学, 大学院・医歯薬保健学研究院, 教授 (40214738)

Co-Investigator(Kenkyū-buntansha) TAKENAKA Joji  広島大学, 病院, 医科診療医 (70526194)
Co-Investigator(Renkei-kenkyūsha) KANEKO Makoto  大阪大学, 大学院・工学研究科, 教授 (70224607)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2010: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Keywords眼圧測定 / 非接触型眼圧計 / 高速カメラ / 角膜変位量 / 緑内障 / 非接触眼圧計
Research Abstract

Intraocular pressure (IOP), aging, gender were selected as a factor that affect the amount of central corneal deformation during tonometry by non-contact tonometer. The aging effect appears more clearly at the late phase of tonometry than the early phase. Female cornea is more susceptible to aging than male. The differences in amount of deformation between ageing groups is more prominent at central cornea, and the difference of corneal deformation at mid-peripheral cornea represented the difference of gender. We also got the result that indicated the IOP reading at low IOP level is lower than actual IOP.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (58 results)

All 2013 2012 2011 2010

All Journal Article (40 results) (of which Peer Reviewed: 40 results) Presentation (17 results) (of which Invited: 2 results) Book (1 results)

  • [Journal Article] Evaluation of corneal displacement using high-speed photography at the early and late phases of noncontact tonometry2013

    • Author(s)
      Nakakura S, Kiuchi Y, Kaneko M, Mochizuki H, Takenaka J, Yamada K, Kimura Y, Tabuchi H
    • Journal Title

      Invest Ophthalmol Vis Sci

      Volume: 54(4) Pages: 2474-82

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Influence of ocular stiffness on intraocular pressure estimation using Goldmann Applanation Tonometry2013

    • Author(s)
      Shirane M, Kiuchi Y, Otani K, Kurita Y, Kaneko M, Takenaka J
    • Journal Title

      JMBE

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Using the Early Postoperative Intraocular Pressure to Predict Pressure Control After a Trabeculectomy.2013

    • Author(s)
      in press3. Okimoto S, Kiuchi Y, A
    • Journal Title

      J Glaucoma

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Transcriptional Regulation of VEGFA by the Endoplasmic Reticulum Stress Transducer OASIS in ARPE-19 Cells.2013

    • Author(s)
      Miyagi H, Kanemoto S, Saito A, Asada R, Iwamoto H, Izumi S, Kido M, Gomi F, Nishida K, Kiuchi Y, Imaizumi K.
    • Journal Title

      PLOS ONE

      Volume: 8 Issue: 1 Pages: 55155-55155

    • DOI

      10.1371/journal.pone.0055155

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Histological findings of uveal capillaries in rabbit eyes after multiple intravitreal injections of bevacizumab2013

    • Author(s)
      Sugimoto Y, Mochizuki H, Miyagi H, Kawamata S, Kiuchi Y
    • Journal Title

      Curr Eye Res

      Volume: 38(4) Pages: 487-96

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Ocular Volumetry Using Fast High-Resolution MRI during Visual Fixation2013

    • Author(s)
      Tanitame K, Sone T, Miyoshi T, Tanitame N, Otani K, Akiyama Y, Takasu M, Date S, Kiuchi Y, Awai K
    • Journal Title

      AJNR Am J Neuroradiol

      Volume: 34(4) Pages: 870-6

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of corneal displacement using high-speed photography at the early and late phases of noncontact tonometry2013

    • Author(s)
      Nakakura S., Kiuchi Y., Kaneko M., Mochizuki H., Takenaka J., Yamada K., Kimura Y., and Tabuchi H.
    • Journal Title

      Innestigative Ophthalmology and Visual Science

      Volume: 54 Issue: 4 Pages: 2474-2481

    • DOI

      10.1167/iovs.12-11424

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The Applicability of Ganglion Cell Complex Parameters Determined From SD-OCT Images to Detect Glaucomatous Eyes.2013

    • Author(s)
      Arintawati P, Sone T, Akita T
    • Journal Title

      J Glaucoma

      Volume: 22

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Influence of ocular stiffness on intraocular pressure estimation using Goldmann Applanation Tonometry2013

    • Author(s)
      Shirane M,
    • Journal Title

      Journal of Medical and Biological Engineering

      Volume: 6

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Intraocular Pressure of Supine Patients Using Four Portable Tonometers2013

    • Author(s)
      Nakakura S,
    • Journal Title

      Optometry and Vision Science

      Volume: 90

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Deformation of yellow spot area by compulsory increase of eye pressure2012

    • Author(s)
      Kimura Y, Izumi I, Kaneko M, Ikuno Y, Miki A, Jo Y, Kiuchi Y
    • Journal Title

      Conf Proc IEEE Eng Med Biol Soc.

      Pages: 1474-7

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Matrix metalloproteinase and cytokine expression in Tenon fibroblasts during scar formation after glaucoma filtration or implant surgery in rats.2012

    • Author(s)
      Nakamura-Shibasaki M, Ko JA, Takenaka J, Chikama TI, Sonoda KH, Kiuchi Y
    • Journal Title

      Cell Biochem Funct

      Volume: 31 Issue: 6 Pages: 482-488

    • DOI

      10.1002/cbf.2923

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Clinical applications of high-resolution ocular magnetic resonance imaging2012

    • Author(s)
      anitame K, Sone T, Kiuchi Y, Awai K
    • Journal Title

      Jpn J Radiol.

      Volume: 30(9) Pages: 695-705

    • NAID

      50008644671

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] The Applicability ofGanglion Cell Complex Parameters Determined From SD-OCT Images to Detect Glaucomatous Eyes.2012

    • Author(s)
      Arintawati P, Sone T, Akita T, Tanaka J, Kiuchi Y
    • Journal Title

      J Glaucoma.

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Comparison of anterior chamber depth measurements by 3-dimensional optical coherence tomography, partial coherence interferometry biometry, Scheimpflug rotating camera imaging, and ultrasound biomicroscopy2012

    • Author(s)
      Nakakura S, Mori E, Nagatomi N, Tabuchi H, Kiuchi Y.
    • Journal Title

      J Cataract Refract Surg.

      Volume: 38(7) Pages: 1207-13

    • NAID

      120006484394

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Intraocular pressure elevation is a delayed-onset complication after successful vitrectomy for stages 4 and 5 retinopathy of prematurity2012

    • Author(s)
      Iwahashi-Shima C, Miki A, Hamasaki T, Otori Y, Matsushita K, Kiuchi Y, Okada M, Kusaka S
    • Journal Title

      Retina.

      Volume: 32(8) Pages: 1636-42

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Altered stability of mRNAs associated with glaucoma progression in human trabecular meshwork cells following oxidative stress2012

    • Author(s)
      Mochizuki H, Murphy CJ, Brandt JD, Kiuchi Y, Russell P
    • Journal Title

      Invest Ophthalmol Vis Sci

      Volume: 53(4) Pages: 1734-41

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Corneal displacement during tonometry with a noncontact tonometer2012

    • Author(s)
      Kiuchi Y, Kaneko M, Mochizuki H, Takenaka J, Yamada K, Tanaka J
    • Journal Title

      Jpn J Ophthalmol

      Volume: 56(3) Pages: 273-9

    • NAID

      10030626992

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Deformation of yellow spot area by compulsory increase of eye pressure.2012

    • Author(s)
      Kimura Y
    • Journal Title

      Conf Proc IEEE Eng Med Biol Soc

      Volume: 60 Pages: 1474-7

    • DOI

      10.1109/embc.2012.6346219

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Corneal displacement during tonometry with a noncontact tonometer.2012

    • Author(s)
      Kiuchi Y
    • Journal Title

      Jpn J Ophthalmol.

      Volume: 3 Issue: 3 Pages: 273-9

    • DOI

      10.1007/s10384-012-0131-x

    • NAID

      10030626992

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Comeal displacement during tonometry with a noncontact tonometer2012

    • Author(s)
      Kiuchi Y, Kaneko M, et.al
    • Journal Title

      Japanese Journal of Ophthalmology

      Volume: (印刷中)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Intraocular pressure measurement using rebound tonometer for deviated angles and positions in human eyes2012

    • Author(s)
      Takenaka J, Mochizuki H, et al
    • Journal Title

      Curr Eye Ees

      Volume: 37 Issue: 2 Pages: 109-114

    • DOI

      10.3109/02713683.2011.623811

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of corneal thickness and axial length on intraocular pressure and ocular pulse amplitude before and after cataract surgery2011

    • Author(s)
      Tabuchi H, Kiuchi Y, Ohsugi H, Nakakura S, Han Z
    • Journal Title

      CanJ Ophthalmol

      Volume: 46(3) Pages: 242-6

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Latanoprost therapy after sunken eyes caused by travoprost or bimatoprost2011

    • Author(s)
      Nakakura S, Tabuchi H, Kiuchi Y
    • Journal Title

      Optom Vis Sci.

      Volume: 88(9) Pages: 1140-4

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Comparison of drug permeabilities across the blood-retinal barrier, blood-aqueous humor barrier, and blood-brain barrier.2011

    • Author(s)
      Toda R, Kawazu K, Oyabu M, Miyazaki T, Kiuchi Y
    • Journal Title

      J Pharm Sci.

      Volume: 100(9) Pages: 3904-11

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of rebound tonometer for measuring intraocular pressure at deviated angle and position.2011

    • Author(s)
      Takenaka J, Mochizuki H, Kunihara E, Tanaka J, Kiuchi Y
    • Journal Title

      Curr Eye Res

      Volume: 36(5) Pages: 422-8

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Platelet-derived growth factor receptor alpha is associated with oxidative stress-induced retinal cell death.2011

    • Author(s)
      Kanamoto T, Rimayanti U, H O, Kiuchi Y
    • Journal Title

      Curr Eye Res.

      Volume: 36(4) Pages: 336-40

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Papilledema with Camurati-Engelmann disease instigating loss of ganglion cell complex thickness.2011

    • Author(s)
      Okimoto S, Kawahara J, Kiuchi Y
    • Journal Title

      Jpn J Ophthalmol.

      Volume: 55(1) Pages: 83-5

    • NAID

      10029020720

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Cullin5 reduces retinal cell death induced by glutamate toxicity.2011

    • Author(s)
      Kanamoto T, Okumichi H, Rimayanti U, Kiuchi Y
    • Journal Title

      Curr Eye Res.

      Volume: 36(1) Pages: 66-70

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Vascular risk factors in glaucoma: a review2011

    • Author(s)
      Yanagi M, Kawasaki R, Wang JJ, Wong TY, Crowston J, Kiuchi Y
    • Journal Title

      Clin Experiment Ophthalmol.

      Volume: 39(3) Pages: 252-8

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Comparative study of different β-radiation doses for preventing pterygium recurrence.2011

    • Author(s)
      Yamada T, Mochizuki H, Ue T, Kiuchi Y,Takahashi Y, Oinaka M.
    • Journal Title

      Int J Radiat Oncol Biol Phys.

      Volume: 81(5) Pages: 1394-8

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Comparison of the prevalence of plateau iris configurations between angle-closure glaucoma and open-angle glaucoma using ultrasound biomicroscopy2011

    • Author(s)
      Mochizuki H, Takenaka J, Sugimoto Y, Takamatsu M, Kiuchi Y
    • Journal Title

      J Glaucoma

      Volume: 20(5) Pages: 315-8

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 気噴流印加時の曲率に着目した角膜剛性のエイジング評価2011

    • Author(s)
      五所 卓巳, 山田 憲嗣, 東森 充, 金子真, 竹中 丈二, 木内 良明, 戸田 良太郎, 西田 幸二
    • Journal Title

      生体医工学

      Volume: (1347-443X)49巻3号

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of rebound tonometer for measuring intraocular pressure at deviated angle and position2011

    • Author(s)
      Takenaka J, Mochizuki H, et al
    • Journal Title

      Curr Eye Res

      Volume: 36 Issue: 5 Pages: 422-428

    • DOI

      10.3109/02713683.2010.534574

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 空気噴流印加時の曲率に着目した角膜剛性のエイジング評価2011

    • Author(s)
      五所卓巳、山田憲嗣, 他
    • Journal Title

      生体医工学

      Volume: 49 Pages: 469-475

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Twenty-four-hour ocular hypotensive effects of 0.0015% tafluprost and 0.005% latanoprost in healthy subjects2010

    • Author(s)
      Mochizuki H, Itakura H, Yokoyama T, Takamatsu M, Kiuchi Y
    • Journal Title

      Jpn J Ophthalmol

      Volume: 54(4) Pages: 286-90

    • NAID

      10027204390

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Efficacy of amniotic membrane-assisted bleb revision for elevated intraocular pressure after filtering surgery2010

    • Author(s)
      Kiuchi Y, Yanagi M, Nakamura T
    • Journal Title

      Clin Ophthalmol

      Volume: 4 Pages: 839-43

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effect of intravitreal bevacizumab on iris vessels in neovascular glaucoma patients2010

    • Author(s)
      Sugimoto Y, Mochizuki H, Okumichi H, Takumida M, Takamatsu M, Kawamata S, Kiuchi Y
    • Journal Title

      Graefes Arch Clin Exp Ophthalmol

      Volume: 248(11) Pages: 1601-9

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] ロボット手術・診断 ハイパーヒューマン技術からみた緑内障2010

    • Author(s)
      木内良明
    • Journal Title

      医工学治療

      Volume: (1344-1221)22巻1号 Pages: 34-39

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] ハイパーヒューマン技術からみた緑内障2010

    • Author(s)
      木内良明
    • Journal Title

      医工学治療

      Volume: 22(1) Pages: 34-39

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] The scar formation mechanisms in conjunctiva after experimental glaucoma implant surgery may differfrom those after filtering surgery2012

    • Author(s)
      Kiuchi Y
    • Organizer
      10th EGS Congress
    • Place of Presentation
      Copenhagen、デンマーク
    • Year and Date
      2012-06-17
    • Related Report
      2012 Final Research Report
  • [Presentation] Choice of Initial Medical Therapy for Open-Angle Glaucoma.2012

    • Author(s)
      Y.Kiuchi
    • Organizer
      APAO/SOE Busan2012
    • Place of Presentation
      釜山 韓国
    • Related Report
      2012 Final Research Report
  • [Presentation] How can we differentiate the transient IOP elevation after implant surgery from permanent elevation?2012

    • Author(s)
      Kiuchi Y
    • Organizer
      Tube meeting in Gainesville
    • Place of Presentation
      Gainesville アメリカ合衆国
    • Related Report
      2012 Final Research Report
  • [Presentation] Relationship Between The Area And Depth Of The Ganglion Cell Complex Parameters In Glaucoma Patients2012

    • Author(s)
      Kiuchi Y
    • Organizer
      The 2012 ARVO Annual Meeting
    • Place of Presentation
      Fort Lauderdaleアメリカ合衆国
    • Related Report
      2012 Final Research Report
  • [Presentation] Relationship among the ganglion cell complex parameters and visual function parameters2012

    • Author(s)
      Akhyar Latief
    • Organizer
      The 27th Asia-Pacific Academy of Ophthalmology Congress
    • Place of Presentation
      釜山, 大韓民国
    • Related Report
      2012 Annual Research Report
  • [Presentation] Choice of Initial Medical Therapy for Open-Angle Glaucoma2012

    • Author(s)
      Kiuchi Y
    • Organizer
      The 27th Asia-Pacific Academy of Ophthalmology Congress
    • Place of Presentation
      釜山、大韓民国
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Relationship Between The Area And Depth Of The Ganglion Cell Complex Parameters In Glaucoma Patients2012

    • Author(s)
      Kiuchi Y
    • Organizer
      The 2012 ARVO Annual Meeting
    • Place of Presentation
      Fort Lauderdale、アメリカ合衆国
    • Related Report
      2012 Annual Research Report
  • [Presentation] How can we differentiate the transient IOP elevation after implant surgery from permanent elevation?2012

    • Author(s)
      Kiuchi Y
    • Organizer
      Tube meeting in Gainesville
    • Place of Presentation
      Gainesville、アメリカ合衆国
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] The scar formation mechanisms in conjunctiva after experimental glaucoma implant surgery may differ from those after filtering surgery2012

    • Author(s)
      Kiuchi Y
    • Organizer
      10th EGS Congress
    • Place of Presentation
      Copenhagen、デンマーク
    • Related Report
      2012 Annual Research Report
  • [Presentation] Structure-function Relationship and Diagnostic Value of Macular Measurement2011

    • Author(s)
      Paramastri Arintawatia, Kiuchi Y, et al
    • Organizer
      Association for Research in Vision and Ophthalmolog
    • Place of Presentation
      Florida, USA(招待講演)
    • Year and Date
      2011-05-04
    • Related Report
      2011 Annual Research Report
  • [Presentation] Effect of gender and age on degree of corneal displacements during non-contact tonometry2010

    • Author(s)
      Yoshiaki Kiuchi
    • Organizer
      Asia-pacific joint glaucoma congress 2010 taipei
    • Place of Presentation
      台湾
    • Year and Date
      2010-12-04
    • Related Report
      2010 Annual Research Report
  • [Presentation] ソフトコンタクトレンズを装着したときの測定眼圧値の比較2010

    • Author(s)
      中村友美・竹中丈二・國原依里子・木内良明
    • Organizer
      第64回日本臨床眼科学会
    • Place of Presentation
      神戸市
    • Year and Date
      2010-11-13
    • Related Report
      2010 Annual Research Report
  • [Presentation] ソフトコンタクトレンズを装着したときの測定眼圧値の比較2010

    • Author(s)
      中村友美・竹中丈二・國原依里子・木内良明
    • Organizer
      第69回広島地方眼科学会
    • Place of Presentation
      広島市
    • Year and Date
      2010-11-07
    • Related Report
      2010 Annual Research Report
  • [Presentation] Corneal displacements during non-contact tonometry are different for men and women and change with age.2010

    • Author(s)
      Yoshiaki Kiuchi
    • Organizer
      2010 MSD Korea-Japan Glaucoma Symposium (招待講演)
    • Place of Presentation
      釜山 韓国
    • Year and Date
      2010-09-04
    • Related Report
      2012 Final Research Report
  • [Presentation] Corneal displacements during non-contact tonometry are different for men and women and change with age.2010

    • Author(s)
      Yoshiaki Kiuchi
    • Organizer
      2010 MSD Korea-Japan Glaucoma Symposium
    • Place of Presentation
      韓国(招待講演)
    • Year and Date
      2010-09-04
    • Related Report
      2010 Annual Research Report
  • [Presentation] Effect of soft contact lens fitting on the non-contact tonometry readings and corneal behavior during tonometry observed by high speed camera.2010

    • Author(s)
      Yoshiaki Kiuchi
    • Organizer
      World Ophthalmology Congress2010
    • Place of Presentation
      ベルリン、ドイツ
    • Year and Date
      2010-06-05
    • Related Report
      2012 Final Research Report
  • [Presentation] Effect of soft contact lens fitting on the non-contact tonometry readings and corneal behavior during tonometry observed by high speed camera2010

    • Author(s)
      Yoshiaki Kiuchi
    • Organizer
      World Ophthalmology Congress2010
    • Place of Presentation
      ドイツ
    • Year and Date
      2010-06-05
    • Related Report
      2010 Annual Research Report
  • [Book] Glaucoma-Basic and clinical Concepts2011

    • Author(s)
      Yoshiaki Kiuchi, Hideki Mochizuki, et al
    • Total Pages
      590
    • Publisher
      InTech
    • Related Report
      2011 Annual Research Report

URL: 

Published: 2010-08-23   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi