Analyssis of the fate determination mechanism to corneal epithelial cells using fluorescent reporter
Project/Area Number |
22591966
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Ophthalmology
|
Research Institution | Keio University |
Principal Investigator |
YOSHIDA Satoru 慶應義塾大学, 医学部, 特任講師 (50398781)
|
Co-Investigator(Renkei-kenkyūsha) |
SHIMMURA Shigeto 慶應義塾大学, 医学部, 准教授 (00235780)
|
Project Period (FY) |
2010 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
|
Keywords | 眼発生 / 再生医学 / 角膜上皮細胞 / ケラチン12 / 角膜上皮 / ケラチン12 / 幹細胞 |
Research Abstract |
We constructed a K12-DsRed BAC reporter, which express DsRed under the control of Krt12 promoter. The K12-DsRed reporter was introduced into a mouse corneal epithelial cell line, TKE2, and a mouse iPS cell line. An activity that converts bulge stem cells
|
Report
(4 results)
Research Products
(14 results)