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The establishment of the effective culture method of retinal stem / progenitor cells derived from iris tissue and the physiologic function test of differentiated cells

Research Project

Project/Area Number 22591970
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Ophthalmology
Research InstitutionFujita Health University

Principal Investigator

YAMAMOTO Naoki  藤田保健衛生大学, 共同利用研究施設, 准教授 (00267957)

Co-Investigator(Kenkyū-buntansha) TANIKAWA Atsuhiro  藤田保健衛生大学, 医学部, 准教授 (40324412)
OHKUMA Mahito  藤田保健衛生大学, 医学部, 講師 (50329710)
HORIGUCHI Masayuki  藤田保健衛生大学, 医学部, 教授 (70209295)
MIYACHI Ei-ichi  藤田保健衛生大学, 医学部, 教授 (90129685)
Co-Investigator(Renkei-kenkyūsha) SENDA Takao  藤田保健衛生大学, 医学部, 教授 (10187875)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords眼発生 / 再生医学(組織幹細胞による網膜再生) / 網膜再生 / 組織幹細胞 / 虹彩 / 組織前駆細胞 / 網膜神経細胞 / 電気生理 / 細胞選択 / コーティング / Cell selection / 組織幹/前駆細胞 / p75NTR(CD271) / Cell Sort / 幹細胞移植
Research Abstract

When we coated the culture plate surface with lamina collagen gel, the culture cells which were derived from mouse iris tissue were expressed the tissue stem cell marker. Then, we were cultured the nerve-like cells effectively by sorting cells derived from culture human iris tissue. When we cultured tissue stem / progenitor cells derived from human iris tissue in a retinoic acid containing nutrient medium, the cells were differentiated the expressed marker protein of the neural retina cell. Furthermore, the physiologic function of cells were evaluated by the patch clamp method, the cells weredetected with a sodium channel and the potassium channel.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (61 results)

All 2013 2012 2011 2010 Other

All Journal Article (28 results) (of which Peer Reviewed: 14 results) Presentation (27 results) (of which Invited: 1 results) Book (3 results) Remarks (3 results)

  • [Journal Article] Circadian expressions of cardiac ion channel genes in mouse might be associated with the central clock in the SCN but not the peripheral clock in the heart.2013

    • Author(s)
      Tong M., Watanabe E., Yamamoto N., Nagahata-Ishiguro M., Maemura K., Takeda N., Nagai R., Ozaki Y.
    • Journal Title

      Biological Rhythm Research

      Volume: 44 (4) Pages: 519-530

    • Related Report
      2012 Final Research Report
  • [Journal Article] Osteogenic differentiation capacity of human skeletal muscle-derived progenitor2013

    • Author(s)
      Oishi T, Uezumi A, Kanaji A, Yamamoto N, Yamaguchi A, Yamada H, Tsuchida K.
    • Journal Title

      PLoS One

      Volume: 8 Issue: 2 Pages: e56641-e56641

    • DOI

      10.1371/journal.pone.0056641

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Circadian expressions of cardiac ion channel genes in mouse2013

    • Author(s)
      Tong M, Watanabe E, Yamamoto N, Nagahata-Ishiguro M, Maemura K, Takeda N,
    • Journal Title

      Biol Rhythm Res.

      Volume: 44 Pages: 519-530

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 眼刺激性試験代替法の第三者評価報告書.評価対象:眼に対する腐食性および強刺激性評価のためのウシ摘出角膜の混濁および透過性試験.2012

    • Author(s)
      簾内桃子,竹内早苗,増田光輝,山本直 樹,小坂忠司,宮岡悦良.
    • Journal Title

      AATEX-JaCVAM

      Volume: J1 (1) Pages: 1-15

    • Related Report
      2012 Final Research Report
  • [Journal Article] 眼刺激性試験 代替法の第三者評価報告書.評価対象:眼に対する腐食性および強刺激性評価 のためのニワトリ摘出眼を用いた眼刺激性試験法.2012

    • Author(s)
      簾内桃子,小坂忠司,山本直樹,増田光輝,竹内早苗,宮岡悦良
    • Journal Title

      AATEX-JaCVAM

      Volume: J1 (1) Pages: 16-29

    • Related Report
      2012 Final Research Report
  • [Journal Article] The clinical significance of thymidylate synthase expression in human papillomavirus-related oropharyngeal squamous carcinoma.2012

    • Author(s)
      Kato H, Yui T, Yamamoto N, Okada T, Urano M, Sakurai K, Naito K.
    • Journal Title

      Nihon Jibiinkoka Gakkai Kaiho

      Volume: 115 Pages: 957-964

    • NAID

      10031130046

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 眼刺激性試験代替法の第三者評価報告書.評価対象:眼に対する腐食性および強刺激性評価のためのウシ摘出角膜の混濁および透過性試験.2012

    • Author(s)
      簾内桃子,竹内早苗,増田光輝,山本直樹,小坂忠司,宮岡悦良
    • Journal Title

      AATEX-JaCVAM

      Volume: J1 Pages: 1-15

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 激性試験代替法の第三者評価報告書.評価対象:眼に対する腐食性および強刺激性評価のためのニワトリ摘出眼を用いた眼刺激性試験法.2012

    • Author(s)
      簾内桃子,小坂忠司,山本直樹,増田光輝,竹内早苗,宮岡悦良
    • Journal Title

      AATEX-JaCVAM

      Volume: J1 Pages: 16-29

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Characterization of human multicentric osteosarcoma using newly established cells derived from multicentric osteosarcoma.2011

    • Author(s)
      Yamamoto Y., Yamamoto N., Tajima K., Ohno A., Washimi Y., Ishimura D., Washimi O., Yamada H
    • Journal Title

      J Cancer Res Clin Oncol

      Volume: 137 (3) Pages: 423-433

    • Related Report
      2012 Final Research Report
  • [Journal Article] UV B-irradiation enhances the racemization and isomerizaiton of aspartyl residues and production of Nε-carboxymethyl lysine (CML) in keratin of skin2011

    • Author(s)
      Mori Y., Aki K., Kuge K., Tajima S.,Yamanaka N., Kaji Y., Yamamoto N., Nagai R., Yoshii H., Fujii N.,Watanabe M., Kinouchi T., Fujii N.
    • Journal Title

      J. Chromatogr. B

      Volume: 879 (29) Pages: 3303-3309

    • Related Report
      2012 Final Research Report
  • [Journal Article] Phosphate overload induces podocyte injury via type III Na-dependent phosphate transporter.2011

    • Author(s)
      Sekiguchi S., Suzuki A., Asano S., Nishiwaki-Yasuda K., Shibata M., Nagao S., Yamamoto N., Matsuyama M., Sato Y., Yan K., Yaoita E., Itoh M.
    • Journal Title

      Am J Physiol Renal Physiol

      Volume: 300(4)

    • Related Report
      2012 Final Research Report
  • [Journal Article] アトピー白内障-発症までのメカニズム-2011

    • Author(s)
      山本直樹
    • Journal Title

      IOL&RS

      Volume: 25(2) Pages: 154-157

    • NAID

      10029691781

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
  • [Journal Article] 光学顕微鏡で観察する組織標本の作製法-組織の固定から標本作製まで-2011

    • Author(s)
      山本直樹
    • Journal Title

      日本白内障学会誌

      Volume: 23(1) Pages: 40-44

    • NAID

      10029877864

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
  • [Journal Article] D-Amino acids in aged proteins : analysis and biological relevance2011

    • Author(s)
      N.Fujii, Y.Kaji, N.Fujii
    • Journal Title

      J.Chromatogr.B

      Volume: 879 Issue: 29 Pages: 3141-3147

    • DOI

      10.1016/j.jchromb.2011.05.051

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Phosphate overload induces podocyte injury via type III Na-dependent phosphate transporter.2011

    • Author(s)
      Sekiguchi S, Suzuki A, Asano S, Nishiwaki-Yasuda K, Shibata M, Nagao S, Yamamoto N, Matsuyama M, Sato Y, Yan K, Yaoita E, Itoh M.
    • Journal Title

      Am J Physiol RenalPhysiol

      Volume: 300(4) Issue: 4 Pages: 848-856

    • DOI

      10.1152/ajprenal.00334.2010

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Characterization of human multicentric osteosarcoma using newly established cells derived from multicentric osteosarcoma.2011

    • Author(s)
      Yamamoto Y., Yamamoto N., Tajima K., Ohno A., Washimi Y., Ishimura D., Washimi O., Yamada H.
    • Journal Title

      J Cancer Res Clin Oncol.

      Volume: 137(3) Pages: 423-433

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Basic study of retinal stem/progenitor cell separation from mouse iris tissue2010

    • Author(s)
      YamamotoN., Tanikawa A., Horiguchi M
    • Journal Title

      Med Mol Morphol

      Volume: 43 (3) Pages: 139-144

    • NAID

      10026727123

    • Related Report
      2012 Final Research Report
  • [Journal Article] Cultured human corneal epithelial stem/progenitor cells derived from the corneal limbus2010

    • Author(s)
      Yamamoto N., Hirano K., Kojima H., Sumitomo M., Yamashita H., Ayaki M., Taniguchi K., Tanikawa A., Horiguchi M.
    • Journal Title

      In Vitro Cell Dev Biol-Animal

      Volume: 46 (9) Pages: 774-780

    • Related Report
      2012 Final Research Report
  • [Journal Article] Immunohistochemical localization of mitochondrial fatty acid β-oxidation enzymes in Muller cells of the retina.2010

    • Author(s)
      Atsuzawa K., Nakazawa A., MizutaniK., Fukasawa M., Yamamoto N., Hashimoto T., Usuda N.
    • Journal Title

      Histochem Cell Biol

      Volume: 134 (6) Pages: 565-579

    • Related Report
      2012 Final Research Report
  • [Journal Article] Melanocyte stem cells express receptors for canonical Wnt-signaling pathway on their surface2010

    • Author(s)
      Yamada T., Akamatsu H., Hasegawa S., Inoue Y., Date Y., Mizutani H., Yamamoto N., Matunaga K., Nakata S.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 396 (4) Pages: 837-842

    • Related Report
      2012 Final Research Report
  • [Journal Article] Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle.2010

    • Author(s)
      Uezumi A., Fukada S., Yamamoto N., Takeda S., Tsuchida K
    • Journal Title

      Nat Cell Biol

      Volume: 12 (2) Pages: 143-152

    • Related Report
      2012 Final Research Report
  • [Journal Article] Expression of vascular endothelial growth factor and presence of angiovascular cells in tissues from different thyroid disorders.2010

    • Author(s)
      Itoh A., Iwase K., Jimbo S., Yamamoto H., Yamamoto N., Kokubo M., Senda T., Nakai A., Nagagasaka A., Nagasaka T., Hibi Y., Seko T.
    • Journal Title

      World J Surg

      Volume: 34 (2) Pages: 242-248

    • Related Report
      2012 Final Research Report
  • [Journal Article] Basic study of retinal stem/progenitor cell separation from mouse iris tissue.2010

    • Author(s)
      Yamamoto N., Tanikawa A., Horiguchi M.
    • Journal Title

      Med Mol Morphol.

      Volume: 43(3) Pages: 139-144

    • NAID

      10026727123

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cultured human corneal epithelial stem/progenitor cells derived from the corneal limbus.2010

    • Author(s)
      Yamamoto N., Hirano K., Kojima H., Sumitomo M., Yamashita H., Ayaki M., Taniguchi K., Tanikawa A., Horiguchi M.
    • Journal Title

      In Vitro Cell Dev Biol-Animal.

      Volume: 46(9) Pages: 774-780

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Immunohistochemical localization of mitochondrial fatty acid β-oxidation enzymes in Muller cells of the retina.2010

    • Author(s)
      Atsuzawa K., Nakazawa A., Mizutani K., Fukasawa M., Yamamoto N., Hashimoto T., Usuda N.
    • Journal Title

      Histochem Cell Biol.

      Volume: 134 Pages: 565-579

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle.2010

    • Author(s)
      Uezumi A., Fukada S., Yamamoto N., Takeda S., Tsuchida K.
    • Journal Title

      Nat Cell Biol.

      Volume: 12(2) Pages: 143-152

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Age-related changes of p75 Neurotrophin receptor-positive adipose-derived stem cells.2010

    • Author(s)
      Yamada T., Akamatsu H., Hasegawa S., Yamamota N., Yoshimura T., Hasebe Y., Inoue Y., Mizutani H., Uzawa T., Matsunaga K., Nakata S.
    • Journal Title

      J Dermatol Sci.

      Volume: 58(1) Pages: 36-42

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Melanocyte stem cells express receptors for canonical Wnt-signaling pathway on their surface.2010

    • Author(s)
      Yamada T., Akamatsu H., Hasegawa S., Inoue Y., Date Y., Mizutani H., Yamamota N., Matunaga K., Nakata S.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 396(4) Pages: 837-842

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] Wnt/beta-catenin signaling regulates melanocyte stem cell differentiation induced by UVB irradiation.2012

    • Author(s)
      Yamada T., Hasegawa S., Inoue Y., Date Y., Mizutani H., Yamamoto N., Nakata S., Matsunaga K., Akamatsu H.
    • Organizer
      International Society for Stem Cell Research 10th Annual Meeting.
    • Place of Presentation
      Yokohama.
    • Related Report
      2012 Final Research Report
  • [Presentation] 分化誘導した虹彩由来網膜幹/前駆細胞の生理学的機能評価2012

    • Author(s)
      山本直樹、大熊真人、谷川篤宏、堀口正之、宮地栄一
    • Organizer
      第11回日本再生医療学会総会
    • Place of Presentation
      神奈川
    • Related Report
      2012 Final Research Report
  • [Presentation] Wnt/beta-catenin signaling regulates melanocyte stem cell differentiation induced by UVB irradiation.2012

    • Author(s)
      Yamada T., Hasegawa S., Inoue Y., Date Y., Mizutani H., Yamamoto N., Nakata S., Matsunaga K., Akamatsu H.
    • Organizer
      International Society for Stem Cell Research 10th Annual Meeting.
    • Place of Presentation
      Yokohama, JAPAN
    • Related Report
      2012 Annual Research Report
  • [Presentation] Aging alteration of the lens.2012

    • Author(s)
      山本直樹
    • Organizer
      第5回タンパク質の異常凝集とその防御・修復機構に関する研究会
    • Place of Presentation
      大阪
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 分化誘導した虹彩由来網膜幹/前駆細胞の生理学的機能評価.2012

    • Author(s)
      山本直樹、大熊真人、谷川篤宏、堀口正之、宮地栄一
    • Organizer
      第11回日本再生医療学会総会
    • Place of Presentation
      神奈川
    • Related Report
      2012 Annual Research Report
  • [Presentation] 不死化角膜上皮細胞(iHCE-NY)を用いた眼刺激性試験代替法に関する研究.2012

    • Author(s)
      山本直樹、平野耕治、山下宏美、加藤義直、佐藤淳、中村政志、原和宏、谷川篤宏、堀口正之、谷口孝喜、小島肇.
    • Organizer
      日本組織培養学会第85回大会
    • Place of Presentation
      京都
    • Related Report
      2012 Annual Research Report
  • [Presentation] 後発白内障における細胞の凝集・重層化に関する基礎研究.2012

    • Author(s)
      山本直樹.
    • Organizer
      第27回JSCRS学術総会・第51回日本白内障学会総会合同学会
    • Place of Presentation
      東京
    • Related Report
      2012 Annual Research Report
  • [Presentation] 白内障における水晶体組織変化2011

    • Author(s)
      山本直樹
    • Organizer
      第50回日本白内障学会・第26回日本白内障屈折矯正手術学会合同学術集会ウィンターセミナー
    • Place of Presentation
      六本木ヒルズ(東京)(招待講演)
    • Year and Date
      2011-12-03
    • Related Report
      2011 Annual Research Report
  • [Presentation] 虹彩由来網膜幹/前駆細胞の網膜神経細胞への分化誘導と生理学的機能評価2011

    • Author(s)
      山本直樹、大熊真人、谷川篤宏、谷口孝喜、堀口正之、宮地栄一
    • Organizer
      第43回藤田学園医学会誌
    • Place of Presentation
      藤田保健衛生大学(愛知)
    • Year and Date
      2011-10-06
    • Related Report
      2011 Annual Research Report
  • [Presentation] 虹彩由来網膜幹/前駆細胞の分化細胞における生理学的機能評価2011

    • Author(s)
      山本直樹、大熊真人、谷川篤宏、堀口正之、宮地栄一
    • Organizer
      第43回日本臨床分子形態学会総会
    • Place of Presentation
      大阪医科大学(大阪)
    • Year and Date
      2011-09-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] 水晶体の恒常的な透明性維持機構解明に関する研究2011

    • Author(s)
      山本直樹
    • Organizer
      第50回日本白内障学会総会・第26回日本眼内レンズ屈折手術学会総会合同学会抄録集
    • Place of Presentation
      福岡国際会議場(福岡)
    • Year and Date
      2011-06-18
    • Related Report
      2011 Annual Research Report
  • [Presentation] Generation and analysis of a new immortalized human corneal epithelium cell line2011

    • Author(s)
      Yamamoto N., Hirano K., et al
    • Organizer
      2011 In Vitro Biology Meeting
    • Place of Presentation
      North Carolina (USA)
    • Year and Date
      2011-06-06
    • Related Report
      2011 Annual Research Report
  • [Presentation] 水晶体の組織幹細胞と水晶体再生の可能性2011

    • Author(s)
      山本直樹
    • Organizer
      第115回日本眼科学会総会抄録集
    • Place of Presentation
      東京国際フォーラム(東京)(招待講演)
    • Year and Date
      2011-05-13
    • Related Report
      2011 Annual Research Report
  • [Presentation] Generation and analysis of a new immortalized human corneal epithelium cell line.2011

    • Author(s)
      Yamamoto N., Hirano K., Sumitomo M., Yamashita H., Nakamura M., Hara K., Tanikawa A., Horiguchi M., Taniguchi K., Kojima H.
    • Organizer
      2011 In Vitro Biology Meeting
    • Place of Presentation
      North Carolina
    • Related Report
      2012 Final Research Report
  • [Presentation] 水晶体の組織幹細胞と水晶体再生の可能性2011

    • Author(s)
      山本直樹
    • Organizer
      第115回日本眼科学会総会
    • Place of Presentation
      東京
    • Related Report
      2012 Final Research Report
  • [Presentation] 虹彩由来網膜幹/前駆細胞の分化細胞における生理学的機能評価2011

    • Author(s)
      山本直樹、大熊真人、谷川篤宏、堀口正之、宮地栄一
    • Organizer
      第43回日本臨床分子形態学会総会・学術集会
    • Place of Presentation
      大阪
    • Related Report
      2012 Final Research Report
  • [Presentation] 水晶体の恒常的な透明性維持 機構解明に関する研究2011

    • Author(s)
      山本直樹
    • Organizer
      第50回日本白 内障学会総会・第26 回日本眼内レンズ 屈折手術学会総会合同学会
    • Place of Presentation
      福岡
    • Related Report
      2012 Final Research Report
  • [Presentation] 虹彩由来網膜幹/前駆細胞の網膜神経細胞への分化誘導と生理学的機能評価2011

    • Author(s)
      山本直樹、大熊真人、谷川篤宏、谷口孝喜、堀口正之、宮地栄一
    • Organizer
      第43回藤田学園医学会
    • Place of Presentation
      愛知
    • Related Report
      2012 Final Research Report
  • [Presentation] 網膜幹細胞を用いた網膜再生医療研究2010

    • Author(s)
      山本直樹
    • Organizer
      第42回日本臨床分子形態学会総会・学術集会
    • Place of Presentation
      静岡
    • Related Report
      2012 Final Research Report
  • [Presentation] アトピー白内障の発症に関与する因子とそのメカニズムの解明2010

    • Author(s)
      山本直樹
    • Organizer
      第49回日本白内障学会総会・第25回日本眼内レンズ屈折手術学会総会合同学会
    • Place of Presentation
      大阪
    • Related Report
      2012 Final Research Report
  • [Presentation] ヒト虹彩由来細胞から網膜神経細胞への分化誘導2010

    • Author(s)
      山本直樹、谷川篤宏、堀口正之
    • Organizer
      第9回日本再生医療学会総会
    • Place of Presentation
      広島
    • Related Report
      2012 Final Research Report
  • [Presentation] SingleEB培養法を利用した分化誘導因子の探索2010

    • Author(s)
      伊達靖、赤松浩彦、長谷川靖司、山田貴亮、井上悠、水谷宏、山本直樹、松永佳世子、中田悟.
    • Organizer
      第9回日本再生医療学会総会
    • Place of Presentation
      広島
    • Related Report
      2012 Final Research Report
  • [Presentation] 組織再生過程における幹細胞の遊走能の役割.2010

    • Author(s)
      田原千愛、赤松浩彦、長谷川靖司、山田貴亮、吉村知久、水谷宏、山本直樹、松永佳世子、中田悟.
    • Organizer
      第9回日本再生医療学会総会
    • Place of Presentation
      広島
    • Related Report
      2012 Final Research Report
  • [Presentation] 網膜幹細胞を用いた網膜再生医療研究2010

    • Author(s)
      山本直樹
    • Organizer
      第42回日本臨床分子形態学会総会(シンポジウム)
    • Place of Presentation
      三島
    • Related Report
      2010 Annual Research Report
  • [Presentation] アトピー白内障の発症に関与する因子とそのメカニズムの解明.2010

    • Author(s)
      山本直樹
    • Organizer
      第49回日本白内障学会総会(シンポジウム)
    • Place of Presentation
      大阪
    • Related Report
      2010 Annual Research Report
  • [Presentation] ヒト角膜輪部由来角膜上皮細胞の分離・培養2010

    • Author(s)
      山本直樹, 平野耕治, 小島肇, 綾木雅彦, 住友万里子, 山下宏美, 大野亜由美, 田島香里, 谷川篤宏, 谷口孝喜, 堀口正之
    • Organizer
      日本組織培養学会第83回大会
    • Place of Presentation
      岡山
    • Related Report
      2010 Annual Research Report
  • [Presentation] マウス水晶体上皮細胞の不死化細胞の作出2010

    • Author(s)
      山本直樹, 谷川篤宏, 内藤紘策, 綾木雅彦, 小島肇, 平野耕治, 堀口正之
    • Organizer
      第114回日本眼科学会総会
    • Place of Presentation
      名古屋
    • Related Report
      2010 Annual Research Report
  • [Book] 動物実験代替安全性プロトコル集2013

    • Author(s)
      山本直樹、吉村功
    • Publisher
      株式会社 シーエムシー出版
    • Related Report
      2012 Annual Research Report
  • [Book] アトピー白内障-その発症に関与する要因とメカニズム-病気の分子形態学2011

    • Author(s)
      山本直樹
    • Publisher
      学際企画株式会社
    • Related Report
      2012 Final Research Report
  • [Book] 病気の分子形態学(分担著書)2011

    • Author(s)
      山本直樹
    • Total Pages
      370
    • Publisher
      学際企画株式会社
    • Related Report
      2011 Annual Research Report
  • [Remarks]

    • URL

      http://www.fujita-hu.ac.jp/~kyoriken/

    • Related Report
      2012 Final Research Report
  • [Remarks] 共同利用研究施設 研究業績

    • URL

      http://www.fujita-hu.ac.jp/~kyoriken/link.html

    • Related Report
      2012 Annual Research Report
  • [Remarks]

    • URL

      http://www.fujita-hu.ac.jp/~kyoriken/

    • Related Report
      2011 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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