Development of minimally invasive treatment for severe tracheomalacia using drug delivery system and growth factors
| Project/Area Number |
22591977
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Pediatric surgery
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| Research Institution | The University of Tokyo |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KOMURA Makoto 埼玉医科大学, 医学部, 教授 (10422289)
TABATA Yasuhiko 京都大学, 再生医科学研究所, 教授 (50211371)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Keywords | 気管軟化症 / 成長因子 / ドラッグデリバリーシステム / 小児 |
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| Research Abstract |
This study showed that slowly released b-FGF enlarges the tracheal lumen and thickens the cartilage dose-dependently. Symptoms of tracheomalacia usually improve with age. Rapid growth of tracheal cartilage inducedby slowly released b-FGF could possibly act as a novel treatment for tracheaomalacia.
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Report
(4 results)
Research Products
(5 results)
