The role of circulating fibrocytes in keloid diathesis.

Research Project

Project/Area Number	22591988
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Single-year Grants
Section	一般
Research Field	Plastic surgery
Research Institution	Hokkaido University
Principal Investigator	FUNAYAMA Emi 北海道大学, 大学院・医学研究科, 助教 (10533630)
Co-Investigator(Kenkyū-buntansha)	YAMAMOTO Yuhei 北海道大学, 大学院・医学研究科, 教授 (70271674) OYAMA Akihiko 北海道大学, 北海道大学病院, 講師 (70374486) FURUKAWA Hiroshi 北海道大学, 大学院・医学研究科, 講師 (00399924) HAYASHI Toshihiko 北海道大学, 北海道大学病院, 助教 (00432146) 齋藤亮北海道大学, 医学(系)研究科(研究院), 非常勤講師 (70507574)
Project Period (FY)	2010 – 2012
Project Status	Completed (Fiscal Year 2012)
Budget Amount *help	¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000) Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000) Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000) Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords	創傷治癒学 / ケロイド / fibrocyte / ケモカイン / keloid / fibroblast / myofibroblast
Research Abstract	Identification of chemokine (CXCL12) in human keloid tissue using immunohistochemistry(2) Development of a mouse dermal inflammation model using PMA(3) Isolation of human fibrocyte and transfer of human fibrocytes to mice