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Investigation of fundamental information of angiogenic therapy using adipose-derived regenerative cell

Research Project

Project/Area Number 22591994
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Plastic surgery
Research InstitutionTottori University

Principal Investigator

YAMAMOTO Yasutaka  鳥取大学, 大学院・医学系研究科, 特任准教授 (20362882)

Co-Investigator(Kenkyū-buntansha) HISATOME Ichiro  鳥取大学, 大学院・医学系研究科, 教授 (60211504)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords再生医療 / 脂肪細胞 / 動脈硬化 / 幹細胞 / 血管再生
Research Abstract

Adipose-derived regenerative cell (ADRC) have been proved effective for angiogenic therapy in mice hind-limb ischemic model. Under condition of diabetes mellitus and aging, angiogenic efficacy has been diminished, however it is not observed under hypertensive condition. Useful information was brought by our investigation for future research.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (4 results)

All 2013 2012

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (2 results)

  • [Journal Article] Transplantation of freshly isolated adipose tissue-derived regenerative cells enhances angiogenesis in a murine model of hind limb ischemia.2013

    • Author(s)
      Harada Y, Yamamoto Y, Tsujimoto S, Matsugami H, Yoshida A, Hisatome I
    • Journal Title

      Biomed Res

      Volume: 34 Pages: 23-29

    • NAID

      130004470831

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Transplantation of freshly isolated adipose tissue-derived regenerative cells enhances angiogenesis in a murine model of hind limb ischemia.2012

    • Author(s)
      Harada Y
    • Journal Title

      Biomed Res.

      Volume: 34 Pages: 23-29

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Presentation] 新鮮単離状態の脂肪組織由来再生細胞移植による血行改善効果の検討2013

    • Author(s)
      山本康孝
    • Organizer
      第12回日本再生医療学会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Year and Date
      2013-03-23
    • Related Report
      2012 Final Research Report
  • [Presentation] 新鮮単離状態の脂肪組織由来再生細胞移植による血行改善効果の検討2013

    • Author(s)
      原田雄輔
    • Organizer
      日本再生医療学会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2012 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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