Experimental study of the effectiveness of CO2 for the brain protection after cardiopulmonary arrest
| Project/Area Number |
22592008
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Emergency medicine
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| Research Institution | Gunma University |
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Principal Investigator |
OSHIMA Kiyohiro 群馬大学, 医学(系)研究科(研究院), 教授 (60361375)
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| Co-Investigator(Kenkyū-buntansha) |
HAGIWARA Shuichi 群馬大学, 大学院医学系研究科, 助教 (20455992)
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| Project Period (FY) |
2010-04-01 – 2014-03-31
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 心肺停止 / 心肺蘇生 / 脳保護 / 二酸化炭素 / 虚血再灌流傷害 / 自己心拍再開 / アニオンギャップ / アルブミン補正アニオンギャップ / 温阻血 / ATP感受性Kチャンネル |
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| Research Abstract |
WE reported the effectiveness of the introduction of percutaneous cardiopulmonary support system (PCPS) and hemodialysis in patients with cardiopulmonary arrest (CPA) due to accidental hypothermia. We aiso reported that anion gap (AG) and albumin-corrected AG (ACAG) were useful predictors of return of spontaneous circulation (ROSC) in patients with CPA. In addition, we evaluated the usefulness of fibrin degradation products (FDP) and D-dimer levels in blood to predict ROSC in patients with CPA compared with AG and ACAG.
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Report
(5 results)
Research Products
(24 results)
