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Epidemiological study for propaganda of delirium evaluation in critically ill patients and the study to elucidate the mechanismof delirium onset

Research Project

Project/Area Number 22592015
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Emergency medicine
Research InstitutionYamaguchi University

Principal Investigator

TSURUTA Ryosuke  山口大学, 大学院・医学系研究科, 教授 (30263768)

Co-Investigator(Kenkyū-buntansha) MIYAUCHI Takashi  山口大学, 医学部附属病院, 助教 (40380000)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Keywords集中治療医学 / せん妄 / 昏睡 / サイトカイン / 炎症 / 鎮静薬 / 脳機能 / 集中治療
Research Abstract

The object was to study the prevalence and effect of delirium on outcomes of mechanically ventilated critically ill patients. Delirium during ICU stay was not associated with higher mortality but with shorter time to extubation and a shorter ICU length of stay among comatose patients. Serum procalcitonin and interleukin-6 in delirious patients were higher than those in non-delirious ones. Associated factors for delirium were age and use of midazolam and fentanyl.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (38 results)

All 2013 2012 2011 2010

All Journal Article (15 results) (of which Peer Reviewed: 8 results) Presentation (13 results) (of which Invited: 3 results) Book (10 results)

  • [Journal Article] われわれはどこに向かおうとしているのか?-過剰鎮静から無鎮静へ2012

    • Author(s)
      鶴田良介
    • Journal Title

      日本集中治療医学会雑誌

      Volume: 19巻 Pages: 154-156

    • NAID

      10030556146

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] ICUにおける鎮痛・鎮静に関するアンケート調査2012

    • Author(s)
      日本集中治療医学会規格・安全対策委員会 日本集中治療医学会看護部会
    • Journal Title

      日本集中治療医学会雑誌

      Volume: 19巻 Pages: 99-106

    • Related Report
      2012 Final Research Report
  • [Journal Article] 人工呼吸管理における鎮静2012

    • Author(s)
      鶴田良介
    • Journal Title

      Clinical Engineering

      Volume: 23巻 Pages: 31-37

    • Related Report
      2012 Annual Research Report 2012 Final Research Report 2011 Annual Research Report
  • [Journal Article] われわれはどこに向かおうとしているのか?-過剰鎮静から無鎮静へ2012

    • Author(s)
      鶴田良介
    • Journal Title

      日本集中治療医学会雑誌

      Volume: 19 Pages: 154-156

    • NAID

      10030556146

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ICUにおける鎮痛・鎮静に関するアンケート調査2012

    • Author(s)
      日本集中治療医学会規格・安全対策委員会,日本集中治療医学会看護部会
    • Journal Title

      日本集中治療医学会雑誌

      Volume: 19 Pages: 99-106

    • Related Report
      2012 Annual Research Report
  • [Journal Article] われわれはどこに向かおうとしているのか?-過剰鎮静から無鎮静へ2012

    • Author(s)
      鶴田良介
    • Journal Title

      日本集中治療学会雑誌

      Volume: 19 Pages: 154-156

    • NAID

      10030556146

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ICUにおける鎮痛・鎮静に関するアンケート調査2012

    • Author(s)
      日本集中治療医学会規格・安全対策委員会
    • Journal Title

      日本集中治療学会雑誌

      Volume: 19 Pages: 99-106

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 小児重症患者のせん妄評価法:日本語版pCAM-ICU2011

    • Author(s)
      古賀雄二,鶴田良介,山勢博彰
    • Journal Title

      日本クリティカルケア看護学会誌

      Volume: 7巻 Pages: 45-51

    • NAID

      130005086601

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] ICU と非 ICU をしっかり区別しよう!2011

    • Author(s)
      鶴田良介
    • Journal Title

      看護技術

      Volume: 57巻 Pages: 7-11

    • Related Report
      2012 Final Research Report
  • [Journal Article] 人工呼吸器装着中であっても、QOLを向上するには?2011

    • Author(s)
      相楽章江,鶴田良介
    • Journal Title

      Expert Nurse

      Volume: 27巻 Pages: 66-71

    • Related Report
      2012 Final Research Report
  • [Journal Article] Effects of a constant light environment on hippocampal neurogenesis and memory in mice.2011

    • Author(s)
      Fujioka A
    • Journal Title

      Neuroscience Letters

      Volume: 488 Pages: 41-44

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ICUと非ICUをしっかり区別しよう!2011

    • Author(s)
      鶴田良介
    • Journal Title

      看護技術

      Volume: 57 Pages: 7-11

    • Related Report
      2010 Annual Research Report
  • [Journal Article] Prevalence and associated factors for delirium in critically ill patients at a Japanese intensive care unit2010

    • Author(s)
      Tsuruta R, Nakahara T, Miyauchi T, Kutsuna S, Ogino Y, Yamamoto T, Kaneko T, Kawamura Y, Kasaoka S, Maekawa T
    • Journal Title

      General Hospital Psychiatry

      Volume: 32巻 Pages: 607-611

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 集中治療における鎮痛・鎮静2010

    • Author(s)
      古賀雄二,鶴田良介
    • Journal Title

      重症集中治療ケア

      Volume: 9巻 Pages: 43-49

    • Related Report
      2012 Final Research Report
  • [Journal Article] Prevalence and associated factors for delirium in critically ill patients at a Japanese intensive care unit.2010

    • Author(s)
      Tsuruta R
    • Journal Title

      General Hospital Psychiatry

      Volume: 32 Pages: 607-611

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] 「鎮静・鎮痛管理」から「疼痛-不穏-せん妄対処」への変革2013

    • Author(s)
      鶴田良介
    • Organizer
      第40回日本集中治療医学会学術集会(招待講演)
    • Place of Presentation
      長野県松本文化会館(松本)
    • Related Report
      2012 Final Research Report
  • [Presentation] Delirium and coma evaluated in Japanese multi-institutional ICUs: prospective observational study2013

    • Author(s)
      Tsuruta
    • Organizer
      42nd Critical Care Congress
    • Place of Presentation
      San Juan、Puerto Rico (USA)
    • Related Report
      2012 Final Research Report
  • [Presentation] Delirium and coma evaluated in Japanese multi-institutional ICUs: prospective observational study.2013

    • Author(s)
      Tsuruta R
    • Organizer
      42nd Critical Care Congress
    • Place of Presentation
      San Juan, Puerto Rico (USA)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 「鎮静・鎮痛管理」から「疼痛―不穏―せん妄対処」への変革2013

    • Author(s)
      鶴田良介
    • Organizer
      第40回日本集中治療医学会学術集会
    • Place of Presentation
      長野県松本文化会館(松本)
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] ICU せん妄の疫学研究(JEDI study)から獲得したもの2012

    • Author(s)
      鶴田良介
    • Organizer
      第49回日本麻酔学会中国・四国支部学術集会(招待講演)
    • Place of Presentation
      高知文化プラザかるぽーと(高知)
    • Year and Date
      2012-09-08
    • Related Report
      2012 Final Research Report
  • [Presentation] Biomarkers and associated factors for ICU delirium2012

    • Author(s)
      Tsuruta R, Kaneda K, Oda Y, Kawamura Y, Fujita M, Todani M, Tanaka R, Nakahara T, Koga Y, Oshima C, Ogino Y, Fukuda S, Kasaoka S
    • Organizer
      25th Annual Congress of the European Society of Intensive Care Medicine
    • Place of Presentation
      Lisbon、Portugal
    • Related Report
      2012 Final Research Report
  • [Presentation] ICU せん妄の評価・診断2012

    • Author(s)
      鶴田良介
    • Organizer
      第59回日本麻酔学会学術集会(招待講演)
    • Place of Presentation
      神戸ポートピアホテル(神戸)
    • Related Report
      2012 Final Research Report
  • [Presentation] せん妄疫学研究(JEDI study)への道のり2012

    • Author(s)
      鶴田良介
    • Organizer
      第39回日本集中治療医学会学術集会
    • Place of Presentation
      幕張メッセ(千葉)
    • Related Report
      2012 Final Research Report 2011 Annual Research Report
  • [Presentation] Biomarkers and associated factors for ICU delirium2012

    • Author(s)
      Tsuruta R, Kaneda K, Oda Y, Kawamura Y, Fujita M, Todani M, Tanaka R, Nakahara T, Koga Y, Oshima C, Ogino Y, Fukuda S, Kasaoka S
    • Organizer
      25th Annual Congress of the European Society of Intensive Care Medicine
    • Place of Presentation
      Lisbon, Portugal
    • Related Report
      2012 Annual Research Report
  • [Presentation] ICUせん妄の疫学研究(JEDI study)から獲得したもの2012

    • Author(s)
      鶴田良介
    • Organizer
      第49回日本麻酔学会中国・四国支部学術集会
    • Place of Presentation
      高知文化プラザかるぽーと(高知)
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] ICUせん妄の評価・診断2012

    • Author(s)
      鶴田良介
    • Organizer
      第59回日本麻酔学会学術集会
    • Place of Presentation
      神戸ポートピアホテル(神戸)
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] ICUにおける鎮静・鎮痛とせん妄の今日的考え方2011

    • Author(s)
      鶴田良介
    • Organizer
      第38回日本集中治療医学会学術集会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2011-02-24
    • Related Report
      2010 Annual Research Report
  • [Presentation] 鎮静中の患者評価で知っておきたいこと2010

    • Author(s)
      鶴田良介
    • Organizer
      第32回日本呼吸療法医学会学術総会
    • Place of Presentation
      京王プラザホテル
    • Year and Date
      2010-07-24
    • Related Report
      2010 Annual Research Report
  • [Book] 集中治療専門医テキスト2013

    • Author(s)
      鶴田良介
    • Publisher
      総合医学社
    • Related Report
      2012 Final Research Report
  • [Book] パーフェクトガイド 呼吸管理とケア2012

    • Author(s)
      鶴田良介
    • Publisher
      総合医学社
    • Related Report
      2012 Final Research Report
  • [Book] レジデントノート別冊救急・ER ノート52012

    • Author(s)
      鶴田良介
    • Publisher
      羊土社
    • Related Report
      2012 Final Research Report
  • [Book] 救急・集中治療医学レビュー20122012

    • Author(s)
      鶴田良介
    • Publisher
      総合医学社
    • Related Report
      2012 Annual Research Report 2012 Final Research Report
  • [Book] パーフェクトガイド 呼吸管理とケア2012

    • Author(s)
      鶴田良介
    • Publisher
      総合医学社
    • Related Report
      2012 Annual Research Report
  • [Book] レジデントノート別冊救急・ERノート52012

    • Author(s)
      鶴田良介
    • Publisher
      羊土社
    • Related Report
      2012 Annual Research Report
  • [Book] 救急・集中治療医学レビュー20112011

    • Author(s)
      鶴田良介
    • Publisher
      総合医学社
    • Related Report
      2012 Final Research Report
  • [Book] 救急診療指針 改訂第4 版2011

    • Author(s)
      鶴田良介
    • Publisher
      へるす出版
    • Related Report
      2012 Final Research Report
  • [Book] 救急・集中治療医学レビュー20112011

    • Author(s)
      島崎修次
    • Publisher
      総合医学社
    • Related Report
      2010 Annual Research Report
  • [Book] 救急・集中治療医学レビュー20102010

    • Author(s)
      鶴田良介
    • Publisher
      総合医学社
    • Related Report
      2012 Final Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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