Identification of the salivary gland stem cells and elucidation of gene in the stem cells to differentiate into functional acinar cells
| Project/Area Number |
22592056
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Morphological basic dentistry
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| Research Institution | The Nippon Dental University College at Tokyo |
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Principal Investigator |
IKEDA Rie 日本歯科大学東京短期大学, 歯科衛生学科, 教授 (50168150)
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| Co-Investigator(Renkei-kenkyūsha) |
KIKUCHI Kenichiro 日本歯科大学, 生命歯学部, 教授 (80267260)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Keywords | 唾液腺 / 幹細胞 / 腺房細胞 / 交感神経 / 組織・細胞 / 分化遺伝子 |
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| Research Abstract |
During regeneration after ductal obstruction of Stensen-s duct, manystem cells were observed in the duct-like structures in the rat parotidgland. Regeneration of the parotid gland occurs rapidly through anappearance of stem cells. Temporarily increase in sympathetic nerves wasrecognized around the duct-like structures. These results suggest that thesympathetic nerves play an important role in regeneration of rat parotidglands.
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Report
(4 results)
Research Products
(10 results)
