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A functional MRI study on the regulation of stress mediated brain activity by biting.

Research Project

Project/Area Number 22592063
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Functional basic dentistry
Research InstitutionGifu University

Principal Investigator

NAKAMURA Hiroyuki  岐阜大学, 大学院・医学系研究科, 准教授 (10211434)

Co-Investigator(Kenkyū-buntansha) 定藤 規弘  生理学研究所, 大脳皮質機能研究系, 教授 (00273003)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords口腔生理学 / 脳活動 / 運動野 / 下頭頂小葉 / 扁桃体 / fMRI / 噛み締め / ストレス / 脳 / 神経 / 非侵襲的画像計測
Research Abstract

The aim of this study is to identify if the emotional brain activity is modified by biting. We analyzed activation of several brain regions ob human subjects by using functional magnetic resonance imaging (fMRI) under different biting pressure. The biting pressure was monitored using a flat pressure sensor attached to clear retainer and was visually feed-backed to the subjects. Biting activated the occipito-temporal visual areas, the parietal visual association areas, the primary and secondary somatosensory areas, and the primary motor area. We found that the neuronal activity of amygdala was suppressed by biting.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (4 results)

All 2011 2010

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Book (1 results)

  • [Journal Article] Direct projections from the central amygdaloid nucleus to the mesencephalic trigeminal nucleus in rats2011

    • Author(s)
      Shirasu M, Takahashi T, Yamamoto T, Itoh K, Sato S, Nakamura H
    • Journal Title

      Brain Res.

      Volume: 1400 Pages: 19-30

    • DOI

      10.1016/j.brainres.2011.05.026

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Forming a negative impression of another person correlates with activation in medial prefrontal cortex and amygdala2011

    • Author(s)
      Iidaka T, Harada T, Sadato N
    • Journal Title

      Social Cognitive and Affective Neuroscience

      Volume: 6 Issue: 4 Pages: 516-525

    • DOI

      10.1093/scan/nsq072

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The locus coeruleus projects to the mesencephalic trigeminal nucleus in rats2010

    • Author(s)
      Takahashi T, Nakamura H.
    • Journal Title

      Neuroscience Research

      Volume: 68 Pages: 103-106

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Book] Neuroanatomy Research Advances2010

    • Author(s)
      Nakamura H, Itoh K.(Flynn, Callaghen eds.)
    • Total Pages
      279
    • Publisher
      Nova Science Publishers, Inc.
    • Related Report
      2010 Annual Research Report

URL: 

Published: 2010-08-23   Modified: 2019-07-29  

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