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Hypoxia diagnosis by MR spectroscopy and Diffusion Weighted Imaging

Research Project

Project/Area Number 22592091
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Pathobiological dentistry/Dental radiology
Research InstitutionNagasaki University

Principal Investigator

EIDA Sato  長崎大学, 大学院・医歯薬学総合研究科, 助教 (80325662)

Co-Investigator(Kenkyū-buntansha) SUMI Tadateru  長崎大学, 大学院・医歯薬学総合研究科, 助教 (80284701)
SUMI Misa  長崎大学, 大学院・医歯薬学総合研究科, 准教授 (90284702)
KIMURA Yasuo  長崎大学, 大学院・医歯薬学総合研究科, 助教 (30253686)
HOTOKEZAKA Yuka  長崎大学, 大学病院, 講師 (10244089)
SASAKI Miho  長崎大学, 大学病院, 助教 (10437874)
ICHIKAWA Yoko  長崎大学, 大学病院, 助教 (90380857)
NAKAMURA Takashi  長崎大学, 大学院・医歯薬学総合研究科, 教授 (30172406)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywordshypoxia / MRI / ADC / 細胞浮腫 / 細胞壊死 / 口腔扁平上皮癌患
Research Abstract

The purpose of this study was to detect hypoxic area in the malignant tumor by MRI.These results suggest that the plasma membranes are critical determinants of the diffusion characteristics on the cellular level.This can be used to monitor the hypoxia pathways.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (2 results)

All 2012 2011

All Presentation (2 results)

  • [Presentation] 拡散強調を左右する細胞学的要因について2012

    • Author(s)
      榮田 智,佛坂由可,片山郁夫, 山田敏朗 ,中村 卓
    • Organizer
      第53回日本歯科放射線学会総会・学術大会
    • Place of Presentation
      岩手
    • Related Report
      2012 Annual Research Report 2012 Final Research Report
  • [Presentation] In vitro measurement of diffusion coefficient2011

    • Author(s)
      榮田 智, 佛坂由可, 片山郁夫, 山田敏朗, 中村 卓
    • Organizer
      第52回日本歯科放射線学会総会・学術大会第18回 国際歯顎顔面放射線学会併催
    • Place of Presentation
      広島
    • Related Report
      2012 Final Research Report

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Published: 2010-11-30   Modified: 2019-07-29  

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