| Project/Area Number |
22592092
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Pathobiological dentistry/Dental radiology
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| Research Institution | Nagasaki University |
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Principal Investigator |
SUMI Tadateru 長崎大学, 大学院・医歯薬学総合研究科, 助教 (80284701)
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| Co-Investigator(Kenkyū-buntansha) |
SUMI Misa 長崎大学, 医歯薬学総合研究科, 准教授 (90284702)
SASAKI Miho 長崎大学, 大学病院, 助教 (10437874)
KIMURA Yasuo 長崎大学, 医歯薬学総合研究科, 助教 (30253686)
NAKAMURA Takashi 長崎大学, 医歯薬学総合研究科, 教授 (30172406)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 歯科放射線学一般 / 核磁気共鳴撮像法 / 拡散強調撮像法 / 再生医学 / 軟骨 |
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| Research Abstract |
The cartilage tissue, non-invasive evaluation their differentiation, the degree of tissue maturation, or three-dimensional structure of calcification further fine is difficult. The motion is limited by complex extracellular matrix and cell membrane, water molecules that make up 70-80% of the mass of the articular cartilage shows the diffuse component of multiple-multidirectional. In order to understand the relationship between the material properties of the cartilage and motility in the tissue water molecules, the apparent diffusion coefficient in the diffusion-weighted MR imaging is useful. Relates perfusion behavior of the surrounding tissue that would affect the diffusion behavior, using a diffusion weighted imaging obtained from several malignant tumors, presented to study the relationship.
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