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Regenerated cartilage differentiation evaluation method using diffusion weighted MR imaging

Research Project

Project/Area Number 22592092
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Pathobiological dentistry/Dental radiology
Research InstitutionNagasaki University

Principal Investigator

SUMI Tadateru  長崎大学, 大学院・医歯薬学総合研究科, 助教 (80284701)

Co-Investigator(Kenkyū-buntansha) SUMI Misa  長崎大学, 医歯薬学総合研究科, 准教授 (90284702)
SASAKI Miho  長崎大学, 大学病院, 助教 (10437874)
KIMURA Yasuo  長崎大学, 医歯薬学総合研究科, 助教 (30253686)
NAKAMURA Takashi  長崎大学, 医歯薬学総合研究科, 教授 (30172406)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords歯科放射線学一般 / 核磁気共鳴撮像法 / 拡散強調撮像法 / 再生医学 / 軟骨
Research Abstract

The cartilage tissue, non-invasive evaluation their differentiation, the degree of tissue maturation, or three-dimensional structure of calcification further fine is difficult. The motion is limited by complex extracellular matrix and cell membrane, water molecules that make up 70-80% of the mass of the articular cartilage shows the diffuse component of multiple-multidirectional. In order to understand the relationship between the material properties of the cartilage and motility in the tissue water molecules, the apparent diffusion coefficient in the diffusion-weighted MR imaging is useful. Relates perfusion behavior of the surrounding tissue that would affect the diffusion behavior, using a diffusion weighted imaging obtained from several malignant tumors, presented to study the relationship.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (11 results)

All 2012 2011 2010

All Journal Article (5 results) (of which Peer Reviewed: 5 results) Presentation (6 results)

  • [Journal Article] Imaging features of the lacrimal and salivary glands of patients with IgG4-related Mikulicz's disease: a report of three cases2012

    • Author(s)
      Sumi T, Takagi Y, Ichikawa Y, Sumi M, Kimura Y, Nakamura T
    • Journal Title

      Oral Radiology

      Volume: 28 Issue: 2 Pages: 140-145

    • DOI

      10.1007/s11282-012-0085-1

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Apparent diffusion coefficient-based differentiation of cystic lesions of the mandible2012

    • Author(s)
      Eida S, Hotokezaka Y, Katayama I, Ichikawa Y, Tashiro S, Sumi T, Sumi M, Nakamura T
    • Journal Title

      Oral Radiology

      Volume: 28 Issue: 2 Pages: 109-114

    • DOI

      10.1007/s11282-012-0091-3

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Salivary gland tumors : Use of intravoxel incoherent motion MR imaging for assessment of diffusion and perfusion for the differentiation of benign from malignant Tumors2012

    • Author(s)
      Misa Sumi, Marc Van Cauteren, Tadateru Sumi, Makoto Obara, Yoko Ichikawa, and Takashi Nakamura
    • Journal Title

      Radiology

      Volume: 23 Issue: 3 Pages: 770777-770777

    • DOI

      10.1148/radiol.12111248

    • Related Report
      2012 Annual Research Report 2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Efficacy of Diffusion-Weighted Imaging for the Differentiation between Lymphomas and Carcinomas of the Nasopharynx and Oropharynx : Correlations of Apparent Diffusion Coefficients and Histologic Features2011

    • Author(s)
      Ichikawa Yoko, Sumi Misa, Sasaki Miho, Sumi Tadateru, Nakamura Takashi
    • Journal Title

      AJNR Am J Neuroradiol

      Volume: 15 Issue: 4 Pages: 761-766

    • DOI

      10.3174/ajnr.a2834

    • Related Report
      2012 Annual Research Report 2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Multiparametric MR imaging of sinonasal diseases : time-signal intensity curve-and apparent diffusion coefficient-based differentiation between benign and malignant lesions2011

    • Author(s)
      Sasaki M, Sumi M, Eida S Nakamura T, etc
    • Journal Title

      AJNR Am J Neuroradiol

      Volume: 32 Issue: 11 Pages: 2154-2159

    • DOI

      10.3174/ajnr.a2675

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Presentation] Intravoxel incoherent motion(IVIM)MRIの唾液腺腫瘍への応用2011

    • Author(s)
      角 美佐, 佐々木美穂, 角 忠輝, 木村泰男, 高木幸則, 榮田 智,市川陽子,中村 卓
    • Organizer
      第16回臨床画像大会
    • Place of Presentation
      新潟
    • Year and Date
      2011-10-01
    • Related Report
      2012 Final Research Report
  • [Presentation] iPadを利用した放射線画像教育システムの構築2011

    • Author(s)
      木村泰男, 山田敏朗, 佐々木美穂, 高木幸則, 榮田 智, 市川陽子, 角 忠輝,角 美佐, 中村 卓
    • Organizer
      第16回臨床画像大会
    • Place of Presentation
      新潟
    • Year and Date
      2011-10-01
    • Related Report
      2012 Final Research Report
  • [Presentation] DWI of lymphomas and carcinomas in the nasopharynx and oropharynx2011

    • Author(s)
      市川陽子, 角 美佐, 佐々木美穂, 角 忠輝, 中村 卓
    • Organizer
      第18回 国際歯顎顔面放射線学会 第52回日本歯科放射線学会総会・学術大会併催
    • Place of Presentation
      広島
    • Year and Date
      2011-05-25
    • Related Report
      2012 Final Research Report
  • [Presentation] 鼻・副鼻腔疾患のマルチパラメトリックMRイメージング2010

    • Author(s)
      佐々木 美穂, 木村 泰男, 角 忠輝, 片山 郁夫, 佛坂 由可, 中村 卓
    • Organizer
      第30回日本歯科放射線学会関西・九州合同地方会
    • Place of Presentation
      北九州
    • Year and Date
      2010-12-11
    • Related Report
      2012 Final Research Report
  • [Presentation] MR factor analysisを用いた被膜浸潤の診断2010

    • Author(s)
      角 美佐, 木村 泰男, 高木 幸則, 角 忠輝, 佐々木 美穂, 栄田 智, 市川陽子、 中村 卓
    • Organizer
      第15回臨床画像大会
    • Place of Presentation
      鹿児島
    • Year and Date
      2010-09-04
    • Related Report
      2012 Final Research Report
  • [Presentation] PET/CT 検査において壊死病巣か・扁平上皮癌リンハ・節転移診断に与える影響2010

    • Author(s)
      角 忠輝,木村泰男,角 美佐, 中村卓
    • Organizer
      51回日本歯科放射線学会総会・学術大会
    • Place of Presentation
      横浜
    • Year and Date
      2010-04-24
    • Related Report
      2012 Final Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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