Project/Area Number |
22592100
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Pathobiological dentistry/Dental radiology
|
Research Institution | Keio University |
Principal Investigator |
ASODA Seiji 慶應義塾大学, 医学部, 講師 (80296706)
|
Co-Investigator(Kenkyū-buntansha) |
YOSHIKAWA Momoko 慶應義塾大学, 医学部, 研究員(非常勤) (50570967)
|
Co-Investigator(Renkei-kenkyūsha) |
SAYA Hideyuki 慶應義塾大学, 医学部, 教授 (80264282)
|
Project Period (FY) |
2010 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
|
Keywords | 実験腫瘍学 / 腫瘍生物学 / 口腔扁平上皮癌 / EMT / CD44 |
Research Abstract |
Epithelial mesenchymal transition (EMT) and stem cell-like characteristics are important phenomena for predicting the degree of malignancy and treatment resistance of oral squamous cell carcinoma (OSCC) . CD44 is a major marker for stem-like cancer cells
|