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Developement of the method for biocompatible resin composite system utilizing with colloidan platinum nano -particles.

Research Project

Project/Area Number 22592107
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Conservative dentistry
Research InstitutionIwate Medical University

Principal Investigator

NODA Mamoru  岩手医科大学, 歯学部, 教授 (10301889)

Co-Investigator(Kenkyū-buntansha) SANO Hidehiko  北海道大学, 大学院・歯学研究科, 教授 (90205998)
中沖 靖子  北海道大学, 歯学研究科(研究院), 助教 (50302881)
Co-Investigator(Renkei-kenkyūsha) NAKAOKI Yasuko  北海道大学, 大学院・歯学研究科, 助教 (50302881)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords保存修復学 / ラジカル / アポトーシス / 白金 / ナノコロイド / ストレス / 修復 / 白金ナノコロイド / 細胞 / 修復法
Research Abstract

Light cured dental resin composites were cured by utilizing free radicals. However, the radical sometimes alter intracellular metabolism and shows toxic effect. In the present study, the possibility of colloidal platinum nanoparticles, which have an ability to scavenge free radicals, to decrease cellular stress during curing light cured resin composites was investigated.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (5 results)

All 2011 2010

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (2 results)

  • [Journal Article] Colloidal platinum nanoparticles increase mitochondrial stress induced by resin composite components2011

    • Author(s)
      Kachi H, Noda M, Wataha JC, Nakaoki Y, Sano H.
    • Journal Title

      J Biomed Mater Res B Appl Biomater.

      Volume: 2 Pages: 193-8

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Colloidal platinum nanoparticles increase mitochondrial stress induced by resin composite components2011

    • Author(s)
      H.Kachi, M.Noda, et al
    • Journal Title

      Journal of biomedical materials research B, applied biomaterials

      Volume: 96 Pages: 191-198

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Colloidal platinum nanoparticles increase mitochondrial stress induced by resin composite components.2010

    • Author(s)
      Kachi H, Noda M, Wataha JC, Nakaoki Y, Sano H.
    • Journal Title

      J Biomed Mater Res B Appl Biomater.

      Volume: 96 Pages: 193-198

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] #3675 Effect of Colloidal Platinum Nano-particles on Monocytes.2010

    • Author(s)
      H. Kachi, M. Noda, Y. Nakaoki , H. Sano
    • Organizer
      IADR
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2010-07-16
    • Related Report
      2012 Final Research Report
  • [Presentation] Effect of colloidal platinum nano-particles on monocytes2010

    • Author(s)
      Kachi H, Noda M, Wataha JC, Nakaoki Y, Sano H.
    • Organizer
      IADR
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2010-07-14
    • Related Report
      2010 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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