The effect of chlorhexidine to improve dentin bond durability
Project/Area Number |
22592114
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Conservative dentistry
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Research Institution | Tokyo Medical and Dental University |
Principal Investigator |
HIRAISHI Noriko 東京医科歯科大学, 医歯(薬)学総合研究科, 助教 (20567747)
|
Project Period (FY) |
2010-04-01 – 2013-03-31
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Project Status |
Completed (Fiscal Year 2013)
|
Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
|
Keywords | クロルヘキシジン / 歯科材料 / 象牙質 / 親水性 / 接着歯学 / レジン / 抗菌作用 / MMPs / 接着強さ / MMAレジンセメント / Self-etch接着システム / 抗菌性 / pH cycling法 / 根面う蝕 |
Research Abstract |
I studied the effect of chlorhexidine incorporation into experimental dentin adhesives with different hydrophilicities on the chlorhexidine release and the microtensile bond strength to dentin after 24 h and 14 months after specimen preparation. The more chlorhexidine released the more hydrophilic resin co-monomers. Significant reduction in bond strength was observed in all adhesive groups, except for chlorhexidine-containing most hydrophobic adhesive. Also, MMA-based resin was used to measure chlorhexidine-release from resin cement by means of HPLC, and antibacterial effect against Streptococcus mutans and Enterococcus faecalis. The 3.0 and 4.0% chlorhexidine-incorporated cement exhibited chlorhexidine release for 5 weeks; however, more than 98% of chlorhexidine was retained in resin matrix. The 3.0 and 4.0% chlorhexidine-incorporated resin cement possessed prolonged chlorhexidine release and antibacterial properties for 2 weeks.
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Report
(4 results)
Research Products
(20 results)
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[Presentation] Glutathione Detoxification of 2-hydroxyethylmethacrylate and Its Effect on Bond Strength2013
Author(s)
Nassar Mohannad, Hiraishi Noriko, Islam Md.Sofiqul, Yukihiko Tamurad, Masayuki Otsukia, Shohei Kasugaie, Keiichi Ohyad, Junji Tagamia, Tay Flanklin
Organizer
IADR/AADR/CADR General Session, (Oral presentation)
Place of Presentation
Washington Convention Center, Seattle, Washington. USA
Related Report
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