Relationship between acid-base resistant zone and nanoleakage expression at the adhesive-dentin interface

• Project/Area Number: 22592116
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Conservative dentistry
• Research Institution: Tokyo Medical and Dental University
• Principal Investigator: NIKAIDO Toru 東京医科歯科大学, 大学院・医歯学総合研究科, 講師 (00251538)
• Project Period (FY): 2010 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000); Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
• Keywords: 樹脂含浸層 / 象牙質の接着 / ボンディングシステム / ナノリーケージ / Acid-base resistant zone / 接着 / 二次齲蝕 / セルフエッチングプライマー / acid-base resistant zone / 機能性モノマー / 接着界面 / ボンディング材

Research Abstract

The acid-base resistant zone (ABRZ) is created at theadhesive-dentin interface under the hybrid layer (HL) after the acid-base challenge.The purpose of this study was to evaluate nanoleakage expression in HL and ABRZusing self-etch adhesives. The TEM observations revealed that the nanoleakageexpressions in HL and ABRZ were formed in all the adhesives, however, those werematerial dependent.

Research Products

• [Journal Article] Phosphoric acid-etching promotes bond strength and formation of ABRZ on enamel. (2013)
  • Author(s): Li N
  • Journal Title: Oper Dent Volume: 38 Pages: 82-90
  • Peer Reviewed
• [Journal Article] レジンコーティング法で歯を守る・強化する、 Super Tooth という新しい考え方 (2012)
  • Author(s): 二階堂徹、田上順次
  • Journal Title: 日本歯科医師会雑誌 Volume: 64(11) Pages: 35-43
• [Journal Article] Protection and reinforcement of tooth structures by dental coating materials (2012)
  • Author(s): Nikaido T, Takahashi R, Ariyoshi M, Sadr A, Tagami J
  • Journal Title: Coatings Volume: 2 Pages: 210-220
  • Peer Reviewed
• [Journal Article] Hydroxyapatite crystal protection against acid-attack beneath resin-dentin interface with four adhesives: TEMand crystallography evidence (2012)
  • Author(s): Nurrohman H, Nikaido T, Takagaki T, Sadr A, Ichinose S, Tagami J
  • Journal Title: DentMater Mater 2012 Jul Volume: 28(7)
  • Peer Reviewed
• [Journal Article] Morphological categorization of acid-base resistant zones withself-etching primer adhesive systems (2012)
  • Author(s): Inoue G, Nikaido T, Sadr A, Tagami J
  • Journal Title: Dent Mater J Volume: 31(2) Pages: 232-238
  • NAID: 10030128966
  • Peer Reviewed
• [Journal Article] Ultra-morphologies of thedentin acid-base resistant zone of two-step self-etching systems after long-term storage in water (2012)
  • Author(s): Ichikawa C, Nikaido T, Inoue G, SadrA, Tagami J
  • Journal Title: J Adhes Dent Volume: 14(3) Pages: 207-213
  • Peer Reviewed
• [Journal Article] Dentin bonding performance and ability of four MMA-based adhesive resins to prevent demineralization along the hybrid layer (2012)
  • Author(s): Nurrohman H
  • Journal Title: J Adhes Dent Volume: 14 Pages: 339-348
  • Peer Reviewed
• [Journal Article] Ultra-morphologies of the dentin acid-base resistant zone of two-step self-etching systems after long-term storage in water. (2012)
  • Author(s): Ichikawa C
  • Journal Title: J Adhes Dent Volume: 14 Pages: 207-213
  • Peer Reviewed
• [Journal Article] Morphological categorization of acid-base resistant zones with self-etching primer adhesive systems. (2012)
  • Author(s): Inoue G
  • Journal Title: Dent Mater J Volume: 31 Pages: 232-238
  • Peer Reviewed
• [Journal Article] Hydroxyapatite crystal protection against acid-attack beneath resin-dentin interface with four adhesives: TEM and crystallography evidence. (2012)
  • Author(s): H. Nurrohman
  • Journal Title: Dent Mater Volume: 28
  • Peer Reviewed
• [Journal Article] Effect of functional monomers in all-in-one adhesive systems on formation of enamel/dentin acid-base resistant zone (2011)
  • Author(s): Nikaido T, Chikawa C, Li N, Takagaki T, Sadr A Yoshida Y, Suzuki K, Tagami J
  • Journal Title: Dental Materials Journal Volume: 30 Pages: 576-582
  • NAID: 10029480351
  • Peer Reviewed
• [Journal Article] Effect of curing modes of dual-cured core systems on microtensile bond strength to dentin and formation of acid-base resistant zone (2011)
  • Author(s): Li N, Takagaki T, Sadr A, Waidyasekera K, Ikeda M, Chen J, Nikaido T, Tagami J
  • Journal Title: J Adhes Dent Volume: 13 Pages: 527-525
  • NAID: 130006962057
  • Peer Reviewed
• [Journal Article] New strategy to create"Super Dentin"using adhesive technology;Reinforcement of adhesive-dentin interface and protection of tooth structures. (2011)
  • Author(s): Nikaido T, Inoue G, Takagaki T, Waydeasekera K, Iida Y, Shinohara SM, Sadr A, Tagami J.
  • Journal Title: Japanese Dental Science Review Volume: 47 Pages: 31-42
  • NAID: 10027850100
  • Peer Reviewed
• [Presentation] 酸-塩基処理後の接着界面におけるナノリ-ケージのTEM観察 (2012)
  • Author(s): 二階堂徹, 高垣智博, ヌロマンハミド, 田上順次
  • Organizer: 第30回日本接着歯学会学術大会
  • Place of Presentation: 函館
• [Presentation] Nanoleakage expression in hybrid layer and acid-base resistant zone (2012)
  • Author(s): Nikaido T, Nurrohman H, Waidyasekera K, Takagaki T, Sadr A, Tagami J
  • Organizer: IADR2012, Iguacu falls
  • Place of Presentation: Brazil
• [Presentation] TEM Study on acid-base resistance of the dentin-adhesive interface (2012)
  • Author(s): Nurrohman H, Nikaido T, Takagaki T, SadrA, Ichinose S, Tagami J
  • Organizer: AADR, Tampa, FL
• [Presentation] Relationship between F-release and morphology of acid-base resistant zones (2012)
  • Author(s): Kirihara M, Inoue G, Nikaido T, Ikeda M, Sadr A, Tagami J
  • Organizer: IADR2012, Iguacu falls
  • Place of Presentation: Brazil
• [Presentation] Nanoleakage expression in hybrid layer and acid-base resistant zone. (2012)
  • Author(s): Toru Nikaido
  • Organizer: IADR2012
  • Place of Presentation: Iguacu falls, Brazil
• [Presentation] Recent Progress in Adhesive Materials and Techniques (2012)
  • Author(s): Toru Nikaido
  • Organizer: 12th International Congress of Iranian Academy of Restorative Dentistry
  • Place of Presentation: Tabriz, Iran
  • Invited
• [Presentation] Single-visit Esthetic Dentistry; Self-reinforcing all-in-one adhesive and wide shade-matching resin composite (2012)
  • Author(s): Toru Nikaido
  • Organizer: Sino Dental 2012 “Japan Advanced Dental Seminar”
  • Place of Presentation: Bejing,l China
  • Invited
• [Presentation] TEM study on acid-base resistance of the dentin-adhesive interface (2012)
  • Author(s): Nurrohman H, Nikaido T, Takagaki T, Sadr A, Ichinose S, Tagami J
  • Organizer: AADR2012
  • Place of Presentation: Tampa, FL, USA
• [Presentation] 顕微ラマン分光法を用いたacid-base resistant zoneの解析 (2012)
  • Author(s): 高垣智博, 二階堂徹, 田上順次
  • Organizer: 第30回日本接着歯学会学術大会
  • Place of Presentation: 函館
• [Presentation] 酸一塩基処理後の接着界面におけるナノリ-ケージのTEM観察 (2012)
  • Author(s): 二階堂徹, 高垣智博, ヌロマンハミド, 田上順次
  • Organizer: 第30回日本接着歯学会学術大会
  • Place of Presentation: 函館
• [Presentation] Innovations in minimal intervention concept. Scope of self-etch adhesive system (2011)
  • Author(s): Nikaido T
  • Organizer: Academic conference, "Minimal Intervention & Update in Restorative Dentistry"
  • Place of Presentation: Srinakharinwirot University, Bangkok
  • Year and Date: 2011-08-23
• [Presentation] Relationship between nanoleakage and acid-base resistantzone (2011)
  • Author(s): Nikaido T
  • Organizer: 4th TAD
  • Place of Presentation: Seoul, South Korea
• [Presentation] Pre-etching promotes bond strength and formation of ABRZ on enamel (2011)
  • Author(s): Li N, Nikaido T, Chen JH, Takagaki T, Tagami J
  • Organizer: 4th TAD
  • Place of Presentation: Seoul, South Korea
• [Presentation] A unique interfacial structure, "Super Dentin" created by self-etching technique (2011)
  • Author(s): Nikaido T
  • Organizer: Start-up symposium for innovative materials research "A Roadmap for the Future of Oral Biomaterials"
  • Place of Presentation: Osaka University
• [Presentation] Effect of fluoride concentration in adhesives on morphology of acid-base resistant zones (2011)
  • Author(s): Kirihara M, Inoue G, Nikaido T, Tagami J
  • Organizer: 13th Joint-Scientific Meeting of KACD and JSCD
  • Place of Presentation: Seoul, Korea
• [Presentation] Nanoleakage properties of the acid-base resistant zone (2011)
  • Author(s): Waidyasekera K, Nikaido T, Nurrohman H, Tagami J.
  • Organizer: 第29回日本接着歯学会学術大会
  • Place of Presentation: 岡山
• [Presentation] New strategy to create "Super Dentin" using adhesive technology;Reinforcement of adhesive-dentin interface and protection of tooth structures. (2010)
  • Author(s): Nikaido T.
  • Organizer: ACTA
  • Place of Presentation: Netherland
  • Year and Date: 2010-10-25
• [Presentation] New concept of enamel/dentin bonding mechanism. (2010)
  • Author(s): Nikaido T
  • Organizer: TMDU-UIC Restorative Dentistry Joint Symposium
  • Place of Presentation: Barcelona, Spain
  • Year and Date: 2010-07-14
• [Presentation] Effect of functional monomers on ultrastructure of acid-base resistant zone. (2010)
  • Author(s): T.Nikaido, C.Ichikawa, N.Li, T.Takagaki, Y.Yoshida, K.Suzuki, J.Tagami.
  • Organizer: 88^<th> IADR
  • Place of Presentation: Barcelona, Spain
• [Book] るう蝕、削らないう蝕 (2013)
  • Author(s): 二階堂徹、高垣智博、田上順次
  • Publisher: 今里聡監修、林美加子、伊藤中編集、クインテッセンス出版
• [Book] 接着治療失敗回避のためのポイント45、なぜ付かないのか、なぜ治らないのか (2010)
  • Author(s): 安田登、二階堂徹、秋本尚武、遠山佳之編
  • Total Pages: 250
  • Publisher: クインテッセンス出版