| Project/Area Number |
22592121
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Conservative dentistry
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| Research Institution | The University of Tokushima |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
TAKAHASHI Kanako 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 助教 (80403715)
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| Co-Investigator(Renkei-kenkyūsha) |
ISHIKAWA Kunio 九州大学, 大学院・歯学研究院, 教授 (90202952)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | スメア層 / フッ化ジアミンシリケート / フッ化ジアンミン銀 / フッ素 / 抗菌成分 / 象牙細管 / 齲蝕 / ハイドロキシアパタイト / 塩化セチルピリジニウム / 粉末Ｘ線回折 / 齲蝕予防 / S. mutans |
|---|
| Research Abstract |
Diamine silver fluoride (Saforide) is clinical use for prevent of progress of dental caries and desensitizing for hypersensitive tooth. Unfortunately, diamine silver fluoride stained tooth black due to silver deposition. To overcome this drawback, ammonium hexafluorosilicatewas prepared. Comparing the antibacterial activity, ammonium hexafluorosilicate seems to be inferior to diamine silver fluoride. To increase the antibacterial activity of ammonium hexafluorosilicate, several antibacterial agents have been added to ammonium hexafluorosilicate solution. The antibacterial activity of ammonium hexafluorosilicate with the addition of antibacterial agents was increased, therefore, ammonium hexafluorosilicate is useful for prevention of dental caries.
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