| Project/Area Number |
22592143
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Prosthetic dentistry
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
TAKAHASHI Toshiyuki 東京医科歯科大学, 大学院・医歯学総合研究 科, 助教 (80360923)
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| Co-Investigator(Kenkyū-buntansha) |
UENO Toshiaki 東京医科歯科大学, 大学院・医歯学総合研究 科, 准教授 (30292981)
KATO Tsuyoshi 東京医科歯科大学, 医学部付属病院, 助教 (80447490)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 高気圧酸素治療 / 歯牙再植 / 再植 / スポーツ歯学 / 外傷 / ラット / 高気圧酸素療法 / 抜歯 / 創傷治癒 |
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| Research Abstract |
The aim of the present study was to investigate the effect of hyperbaric oxygen (HBO) on the healing of the replanted molar in rat. Group 1 consisted of rats which underwent HBO, and Group 2 consisted of rats receiving no treatment. Group2 rats were given HBO (100% oxygen at 2.5 atmosphere absolute) for 120 minutes per day for five days, beginning the day of surgery. The experimental tissues in both groups were removed at 7 day after operation. By histological evaluation, the HBO therapy seemed to increased microvessel density and fibroblast in periodontal tissues of replanted molar. It was suggested that HBO therapy has a positive effects on the healing of the replantedmolar in rat.
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