Chewing-induced regional brain activity and cognitive function in elderly patients wearing implant-supported dentures
| Project/Area Number |
22592169
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Prosthetic dentistry
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| Research Institution | Kanagawa Dental College |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
ONO Yumie 明治大学, 理工学部電気電子生命学科, 准教授 (10360207)
ONOZUKA Minoru 日体柔整専門学校, 校長 (90084780)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Keywords | fMRI, NIRS, 咀嚼 / 背外側前頭前野 / 光トポグラフィー / N-Back 課題 / 認知機能 / 咀嚼 / N-back課題 / NIRS-SPM解析 / NIRS / 前頭前野 / ウェルニッケ野 / NIRS-SPM / fMRI / インプラント義歯 / BOLD法 |
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| Research Abstract |
We used functional magnetic resonance imaging(fMRI) and near-infrared spectroscopy(NIRS) to investigate changes in regional brain activity during gum chewing, and the effect of chewing on memory acquisition during a working memory task in elderly patients who wore conventional and implant-supported dentures.Despite the limitation of a small sample size, our results indicated that during the gum-chewing task, neural activity in the prefrontal cortex (PFC) differed between the two prosthodontic therapies.Whether the PFC neural activity was related to cognitive function, however, was unclear.
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Report
(4 results)
Research Products
(20 results)
