Tissue reaction around the implants coated with cell adhesive protein using the tresyl chloride method.

• Project/Area Number: 22592189
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Dental engineering/Regenerative dentistry
• Research Institution: Yokohama City University
• Principal Investigator: OZAWA Tomomichi 横浜市立大学, 附属病院, 助教 (30381479)
• Co-Investigator(Kenkyū-buntansha): HAYAKAWA Touru 鶴見大学, 歯学部, 教授 (40172994) ; HIROTA Makoto 横浜市立大学, 医学部, 准教授 (20347305)
• Project Period (FY): 2010 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000); Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000); Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2010: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
• Keywords: 細胞接着 / インプラント

Research Abstract

We immobilized cell-adhesive protein onto the titanium screw using tresyl chloride method and confirmed that epithelial tissue attached to titanium screwafter the insertion in upper molar extraction socket of rat . The soft tissue adhesion onto the titanium screw suggested the possibility for decreasing peri-implatitis.