A possibility of the single-crystal nanotube apatite

• Project/Area Number: 22592194
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Dental engineering/Regenerative dentistry
• Research Institution: Tokyo Dental College
• Principal Investigator: MIAKE Yasuo 東京歯科大学, 歯学部, 准教授 (00157421)
• Co-Investigator(Renkei-kenkyūsha): OKAZAKI Masayuki 広島大学, 歯学部基礎生命科学部門・生体 材料学, 教授 (30107073) ; SHIMODA Shinji 鶴見大学, 歯学部口腔解剖学, 教授 (30139620)
• Project Period (FY): 2010-04-01 – 2014-03-31
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000); Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000); Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2010: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
• Keywords: 生体材料 / ヒドロキシアパタイト / 結晶成長 / 結晶合性 / 合成結晶 / ハイドロキシアパタイト

Research Abstract

The purpose of this study makes single-crystal nanotube apatite and to apply as biocompatible material. An apatite synthesizer of the wet process was used for an experiment. We used ammonium phosphate and dropped calcium carbonate after having regulated pH with an ammonia solution. We added hydrogen fluoride in solution to improve crystallinity in the latter half of the synthetic experiment. The synthetic crystal was immersed in the lactic acid to empty the aperture of the nanospace into the crystal center.
The stick apatite that the aperture was vacant in the center was observed when we observed crystal after the immersion by a transmission electron microscope. The c-axis section of the crystal was original hexagon, and an aperture was observed in the crystal center. We were able to make tube-shaped single-crystal apatite by the method mentioned above.