| Project/Area Number |
22592208
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Surgical dentistry
|
|---|
| Research Institution | Niigata University |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
IZUMI Naoya 新潟大学, 医歯学総合病院, 助教 (10361908)
KOJIMA Taku 新潟大学, 医歯学系, 助教 (90515777)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
INOUE Kayoko (NOZAWA Kayoko) 新潟大学, 医歯学系, 特任准教授 (90303130)
|
|---|
| Project Period (FY) |
2010 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
|---|
| Keywords | PCR / 発症メカニズム / 下顎骨延長 / ラット実験モデル / マイクロ CT / ＰＣＲ / マイクロCT |
|---|
| Research Abstract |
This study was undertaken to examine the effects of mechanical loadings on the morphology of mandibular condyle following distraction in rat experimental model.10-week-old male Wistar rats received 3.5 mm unilateral mandibular distraction over 10 days after5-day latency period, and the morphological changes of mandibular condyles were examined one day, one week and three weeks after distraction. As a result, the deformation of the condyle with a destruction of cartilage layer and a bone resorption was recognized. These findings indicate thatoverloading to the mandibular condyle is a key factor for PCR.
|
