Neuropathic pain and psychological stress: special reference to the BDNF expression on salivary gland

• Project/Area Number: 22592229
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Surgical dentistry
• Research Institution: Tokai University
• Principal Investigator: OTA Yoshihide 東海大学, 医学部, 教授 (60233152)
• Co-Investigator(Kenkyū-buntansha): AOKI Takayuki 東海大学, 医学部, 准教授 (80297209)
• Project Period (FY): 2010 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000); Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
• Keywords: 神経因性疼痛 / 精神的ストレス / BDNF / 唾液腺 / 口腔 / 慢性疼痛 / 口腔外科手術 / 心因性疼痛 / CgA

Research Abstract

We analyzed the neuropathic pain and psychological outcome of patients following oral surgery.

Research Products

• [Journal Article] IgG4-related disease of the infratemporal fossa: A case report (2013)
  • Author(s): Sato Y, Aoki T, Ota Y, Ogura G, AraiT, Sakamoto Y, Aoyama K, Kaneko A
  • Journal Title: J Oral Maxillofac Surg Med Pathol. Volume: 25 Issue: 1 Pages: 69-73
  • DOI: 10.1016/j.ajoms.2012.05.010
  • Peer Reviewed
• [Journal Article] Lung Metastases of Epithelial-Myoepithelial Carcinoma of the Parotid Gland Successfully Treated With Chemotherapy: A Case Report. (2013)
  • Author(s): Yamazaki H, Ota Y, Aoki T, Kaneko A
  • Journal Title: J Oral Maxillofac Surg. Volume: 71 Issue: 1 Pages: 220-6
  • DOI: 10.1016/j.joms.2012.03.031
  • Peer Reviewed
• [Journal Article] Successful treatment by intralesional steroid injection in management of central giant cell granuloma of the jaw-Report of two cases (2012)
  • Author(s): Aoki T, Karakida K, Sakamoto H, Yamazaki H, Otsuru M, Sasaki M, Sakamoto Y, Aoyama K, Ota Y, KanekoA.
  • Journal Title: J Oral Maxillofac Surg Med Pathol Volume: 24 Issue: 4 Pages: 213-217
  • DOI: 10.1016/j.ajoms.2011.11.007
  • Peer Reviewed
• [Journal Article] Peripheral ameloblastoma of the lower molar gingiva: a case report and immunohistochemical study (2012)
  • Author(s): Kato H, Ota Y, Sasaki M, Karakida K, Kaneko A, Sekido Y, Tsukinoki K
  • Journal Title: Tokai Exp Clin Med. Volume: 37 Pages: 30-4
  • URL: http://mj.med.u-tokai.ac.jp/pdf/370201.pdf
  • Peer Reviewed
• [Journal Article] A phlebolith in the anterior portion of the masseter muscle. (2012)
  • Author(s): Kato H, Ota Y, Sasaki M, Arai T, Sekido Y, Tsukinoki K.
  • Journal Title: Tokai Exp Clin Med. Volume: 37 Pages: 25-9
  • URL: http://mj.med.u-tokai.ac.jp/pdf/370106.pdf
  • Peer Reviewed
• [Journal Article] Huge ameloblastoma associated with hypercalcemia, 6 49 29 38 4 有効数 = 年齢別80～ 60～79 40～59 20～39 0～19GHQ SCORE25242322212019181716151413121110987654321011 14 10 35 56 有効数 = 疾患別E D C B AGHQ SCORE252423222120191817161514131211109876543210126 126 有効数 = 総得点の変化術後 (2012)
  • Author(s): Ota Y, Aoki T, Otsuru M, Hirabayashi K, Nakamura N, Tsukinoki K.
  • Journal Title: J Oral Maxillofac Surg. Volume: 70 Issue: 6 Pages: 1380-5
  • DOI: 10.1016/j.joms.2011.06.003
  • Peer Reviewed
• [Journal Article] Concurrent onset of an eosinophilic ulcer of the oral mucosa with peripheral eosinophilia in a human T-cell leukemia virus type I carrier (2012)
  • Author(s): Yamazaki H, Shirasugi Y, Kajiwara H, Sasaki M, Otsuru M, Aoki T, Ota Y, Kaneko A, Nakamura N.
  • Journal Title: Oral Surg Oral Med Oral Pathol Oral Radiol Volume: 114 Issue: 1 Pages: e43-e48
  • DOI: 10.1016/j.oooo.2011.12.012
  • Peer Reviewed
• [Journal Article] Development of follicular lymphoma of the cervical lymph nodes in a postoperative patient with tongue cancer (2012)
  • Author(s): Yamazaki H, Nakatogawa N, Ota Y, Karakida K, Otsuru M, Kaneko A, Shirasugi Y, Kajiwara H
  • Journal Title: Oral Surg Oral Med Oral Pathol Oral Radiol Volume: 113 Issue: 6 Pages: e35-e39
  • DOI: 10.1016/j.tripleo.2011.08.026
  • Peer Reviewed
• [Journal Article] Inverted ductal papilloma arising from the buccal minor salivary gland: A case report and immunohistochemical study (2012)
  • Author(s): Hisashi Kato
  • Journal Title: Oral Science International Volume: 9 Issue: 2 Pages: 55-58
  • DOI: 10.1016/s1348-8643(12)00024-9
  • Peer Reviewed
• [Journal Article] Development of follicular lymphoma of the cervical lymph nodes in a postoperative patient with tongue cancer (2012)
  • Author(s): Yamazaki H, Nakatogawa N, Ota Y, Karakida K, Otsuru M, Kaneko A, Shirasugi Y, Kajiwara H
  • Journal Title: Oral Surg Oral Med Oral Pathol Oral Radiol Endod Volume: (In press)
  • Peer Reviewed
• [Journal Article] Huge Ameloblastoma Associated With Hypercalcemia, Leukocytosis, and Elevated Tumor Markers via Production of Parathyroid Hormone-Related Protein and Granulocyte Colony-Stimulating Factor (2012)
  • Author(s): Ota Y, Aoki T, Otsuru M, Hirabayashi K, Nakamura N, Tsukinoki K
  • Journal Title: J Oral Maxillofac Surg Volume: (In press)
  • Peer Reviewed
• [Journal Article] Postoperative follow-up strategy in patients with oral squamous cell carcinoma (2011)
  • Author(s): Sasaki M, Aoki T, Karakida K, Otsuru M, Takahashi M, Akamatsu T, Sakamoto H, Ota Y
  • Journal Title: J Oral Maxillofac Surg Volume: 69 Issue: 4 Pages: e33-e38
  • DOI: 10.1016/j.tripleo.2008.12.019
  • Peer Reviewed
• [Journal Article] Bilateral numb chin syndrome leading to a diagnosis of Burkitt's cell acute lymphocytic leukemia: a case report and literature review (2011)
  • Author(s): Sasaki M, Yamazaki H, Aoki T, Ota Y, Sekiya R, Kaneko A.
  • Journal Title: Oral Surg Oral Med Oral Pathol Oral Radiol Endod Volume: 111 Issue: 3 Pages: e11-e16
  • DOI: 10.1016/j.tripleo.2010.09.066
  • Peer Reviewed
• [Journal Article] Anatomical study of the external carotid artery and its branches for administration of superselective intra-arterial chemotherapy via the superficial temporal artery (2011)
  • Author(s): Yonenaga K, Tohnai I, Mitsudo K, Mori Y, Saijo H, Iwai T, Yonehara Y, Ota Y, Torigoe K, Takato T.
  • Journal Title: Int J Clin Oncol Volume: 16 Issue: 6 Pages: 654-9
  • DOI: 10.1007/s10147-011-0238-y
  • Peer Reviewed
• [Journal Article] Analysis of risk factors for surgical-site infections in 276 oral cancer surgeries with microvascular free-flap reconstructions at a single university hospital. (2010)
  • Author(s): Karakida K, Aoki T, Ota Y, Yamazaki H, Otsuru M, Takahashi M, Sakamoto H, Miyasaka M.
  • Journal Title: J Infect Chemother Volume: 16 Issue: 5 Pages: 334-9
  • DOI: 10.1007/s10156-010-0108-y
  • NAID: 10027190642
  • Peer Reviewed
• [Journal Article] Identification of oral bacteria by 16S rRNA gene analysis in elderly persons requiring nursing care (2010)
  • Author(s): Kurabayashi H, Kaneko A, Sekiya R, Karakida K, Sasaki M, Nakatogawa N, Aoki T, Ota Y, Sakamoto H.
  • Journal Title: J Infect Chemother Volume: 17 Issue: 1 Pages: 40-4
  • DOI: 10.1007/s10156-010-0181-2
  • NAID: 10027816692
  • Peer Reviewed
• [Journal Article] Ameloblastic carcinoma, secondary type: a case report. (2010)
  • Author(s): Karakida K, Aoki T, Sakamoto H, Takahashi M, Akamatsu T, Ogura G, Sekido Y, Ota Y.
  • Journal Title: Oral Surg Oral Med Oral Pathol Oral Radiol Endod Volume: 110 Issue: 6 Pages: e33-e37
  • DOI: 10.1016/j.tripleo.2010.08.018
  • Peer Reviewed
• [Journal Article] Multiple giant cell tumors in maxilla and skull complicating Paget's disease of bone (2010)
  • Author(s): Karakida K, Ota Y, Aoki T, Akamatsu T, Kajiwara H, Hirabayashi K
  • Journal Title: Tokai Exp Clin Med. Volume: 35 Pages: 112-7
  • URL: http://mj.med.u-tokai.ac.jp/pdf/350307.pdf
  • Peer Reviewed
• [Presentation] 客観的基準を用いて切除を行った口底癌68例の検討 (2012)
  • Author(s): 新井 俊弘、太田 嘉英、青木 隆幸
  • Organizer: 第57回日本口腔外科学会総会・学術大会
  • Place of Presentation: 神奈川
  • Year and Date: 2012-10-20
• [Presentation] エナメル上皮癌の臨床病理学的検討 (2012)
  • Author(s): 青木 隆幸、太田 嘉英
  • Organizer: 第57回日本口腔外科学会総会・学術大会
  • Place of Presentation: 神奈川
  • Year and Date: 2012-10-19
• [Presentation] 腔扁平上皮癌の骨転移における接着因子発現異常の影響について (2012)
  • Author(s): 高橋 美穂、 青木 隆幸、太田 嘉英
  • Organizer: 第57回日本口腔外科学会総会・学術大会
  • Place of Presentation: 神奈川
  • Year and Date: 2012-10-19
• [Presentation] 口腔がん遊離再建術症例における術後早期離床の検討 (2012)
  • Author(s): 傳田 祐也、太田 嘉英、青木 隆幸
  • Organizer: 第57回日本口腔外科学会総会・学術大会
  • Place of Presentation: 神奈川
  • Year and Date: 2012-10-19
• [Presentation] 術野外感染(RI)のリスクファクターとしての手術部位感染(SSI)の臨床的検討 (2012)
  • Author(s): 唐木田 一成、太田 嘉英、青木 隆幸
  • Organizer: 第57回日本口腔外科学会総会・学術大会
  • Place of Presentation: 神奈川
  • Year and Date: 2012-10-19
• [Presentation] 歯性感染症閉鎖膿瘍から分離したPrevotella属におけるceftriaxone耐性株の解析第 (2012)
  • Author(s): 金子 明寛、太田 嘉英
  • Organizer: 32回日本歯科薬物療法学会
  • Place of Presentation: 大阪
  • Year and Date: 2012-07-01
• [Presentation] 東海大学大学院がんプロフェッショナル養成プラン口腔顎顔面外科学分野の現状 (2012)
  • Author(s): 太田 嘉英
  • Organizer: 第66回NPO法人日本口腔科学会学術集会
  • Place of Presentation: 広島
  • Year and Date: 2012-05-18
• [Presentation] 当科で行った口腔扁平上皮癌に対する化学療法の検討 (2012)
  • Author(s): 山崎 浩史、太田 嘉英、青木 隆幸
  • Organizer: 第30回日本口腔腫瘍学会総会・学術大会
  • Place of Presentation: 埼玉
  • Year and Date: 2012-01-27
• [Presentation] 口腔扁平上皮癌に対するNCCNガイドラインに基づいた術後化学放射線療法の検討 (2012)
  • Author(s): 大鶴 光信、太田 嘉英、青木 隆幸
  • Organizer: 第30回日本口腔腫瘍学会総会・学術大会
  • Place of Presentation: 埼玉
  • Year and Date: 2012-01-27
• [Presentation] 頭頸部癌に対するCisplatinを含む化学療法・化学放射線療法による有害事象の検討 (2012)
  • Author(s): 新井 俊弘、太田 嘉英、青木 隆幸
  • Organizer: 第30回日本口腔腫瘍学会総会・学術大会
  • Place of Presentation: 埼玉
  • Year and Date: 2012-01-27
• [Presentation] 腹直皮弁の経時的変化の検討 (2012)
  • Author(s): 坂本 由紀、太田 嘉英、青木 隆幸
  • Organizer: 第30回日本口腔腫瘍学会総会・学術大会
  • Place of Presentation: 埼玉
  • Year and Date: 2012-01-27
• [Presentation] 当科における原発性下顎骨内扁平上皮癌の臨床的検討 (2012)
  • Author(s): 鈴木 崇嗣、太田 嘉英、青木 隆幸
  • Organizer: 第30回日本口腔腫瘍学会総会・学術大会
  • Place of Presentation: 埼玉
  • Year and Date: 2012-01-27
• [Presentation] 臨床型分類の再検討 (2012)
  • Author(s): 太田 嘉英
  • Organizer: 第30回日本口腔腫瘍学会総会・学術大会
  • Place of Presentation: 埼玉
  • Year and Date: 2012-01-26
• [Presentation] CLINICOPATHOLOGICAL STUDY OF AMELOBLASTIC CARCINOMA. (2012)
  • Author(s): Takayuki Aoki, Yoshihide Ota, Kazunari Karakida, Hiroshi Yamazaki, Mitsunobu Otsuru, Miho Takahashi, Muneo Miyasaka, Sachi Suzuki.
  • Organizer: 21th Congress of the European Association for Cranio-MaxilloFacial Surgery
  • Place of Presentation: Dubrovnik, Croatia.
• [Presentation] DECISION ANALYSIS AND TREATMENT THRESHOLD IN MANAGEMENT OF TONGUE CANCER WITH N0 NECK STATUS. (2012)
  • Author(s): Mitsunobuo Otsuru*, Yoshi HideOta, Takayuki Aoki, Hiroshi Yamazaki, Miho Takasahi, Kazunari Karakida.
  • Organizer: 21th Congress of the European Association for Cranio-Maxillo- Facial Surgery
  • Place of Presentation: Dubrovnik, Croatia.
• [Presentation] 口腔がんの標準手術Pull-through法による舌半側切除術 (2011)
  • Author(s): 太田 嘉英
  • Organizer: 第56回(社)日本口腔外科学会総会・学術大会
  • Place of Presentation: 大阪
  • Year and Date: 2011-10-22
• [Presentation] 頭頸部癌に対するTPF療法による低Na血症の臨床的検 討 (2011)
  • Author(s): 新井 俊弘、太田 嘉英
  • Organizer: 第56回(社)日本口腔外科学会総会・学術大会
  • Place of Presentation: 大阪
  • Year and Date: 2011-10-22
• [Presentation] 口腔扁平上皮癌N0症例における予防的頸部郭清の検討 (2011)
  • Author(s): 大鶴 光信、太田 嘉英、青木 隆幸
  • Organizer: 第56回(社)日本口腔外科学会総会・学術大会
  • Place of Presentation: 大阪
  • Year and Date: 2011-10-21
• [Presentation] 当科におけるビスフォスフォネート関連顎骨壊死18例の臨床的検討 (2011)
  • Author(s): 鈴木 崇嗣、太田 嘉英、青木 隆幸
  • Organizer: 第56回(社)日本口腔外科学会総会・学術大会
  • Place of Presentation: 大阪
  • Year and Date: 2011-10-21
• [Presentation] 舌癌MRI画像における腫瘍と傍舌感覚の距離と頸部リンパ節転移の検討 (2011)
  • Author(s): 青山 謙一、太田 嘉英、青木 隆幸
  • Organizer: 第56回(社)日本口腔外科学会総会・学術大会
  • Place of Presentation: 大阪
  • Year and Date: 2011-10-21
• [Presentation] ビスフォスフォネート製剤投与患者への対応の現状 (2010)
  • Author(s): 太田 嘉英
  • Organizer: 第4回神奈川県歯科医師会・口腔外科学術集会
  • Place of Presentation: 神奈川
• [Presentation] 病理医に知っていただきたい歯科口腔疾患の知識 (2010)
  • Author(s): 太田 嘉英
  • Organizer: 第91回神奈川県病理医会例会
  • Place of Presentation: 神奈川
• [Presentation] 当科における下顎歯肉扁平上皮癌の臨床的検討 (2010)
  • Author(s): 青木 隆幸、太田 嘉英
  • Organizer: 第64回NPO法人日本口腔科学会
  • Place of Presentation: 北海道