A physiologic role of the melatonin in the formation and the growth of the tooth and the regenerative medicine of the tooth
| Project/Area Number |
22592233
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Surgical dentistry
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| Research Institution | Tsurumi University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
SATOMURA Kazuhito 鶴見大学, 歯学部, 教授 (80243715)
TATEHARA Seiko 鶴見大学, 歯学部, 助教 (90380089)
YAMAMOTO Hideo 鶴見大学, 歯学部, 講師 (10220493)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | メラトニン / 歯 / 歯の再生 |
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| Research Abstract |
Expression found immunohistochemical study for expression of the Mel1aR using human embryos and mouse tooth germs. Expression of Mel1aR in human as well as rat tooth cells, in vitro. Further, significant effect of melatonin on the proliferation of human dental papilla cells melatonin increased expression of odontoblast cells and Osteoblast differentiation markers dependently on the in differentiation of human dental papilla cells.
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Report
(4 results)
Research Products
(9 results)
