Evaluation of roles of Ten-m/Odz3 in periodontal ligament during orthodontic tooth movement.
| Project/Area Number |
22592277
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Orthodontic/Pediatric dentistry
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| Research Institution | Tohoku University |
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Principal Investigator |
YUICHI Sakai 東北大学, 大学院・歯学研究科, 大学院非常勤講師 (00451609)
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| Co-Investigator(Kenkyū-buntansha) |
TOMOHIRO Hukunaga 東北大学, 病院, 講師 (70362994)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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|---|
| Keywords | Ten-m/Odz3 / 歯根膜 / 機械的刺激 / 歯の移動 / 圧迫側 / マウス歯根膜 / Tem-m/Odz3 / 遺伝子発現 |
|---|
| Research Abstract |
Peirodotal ligament (PDL) maintains unmineralized status to exert its functions; however, the molecular mechanisms are unknown. In this study, we focused on Ten-m/Odz3 to clarify molecular mechanism upon PDL homeostasis. As a result, Ten-m/Odz3 expression was shown in PDL. Moreover, the expression pattern was changed by mechanical stress. These findings suggest that Ten-m/Odz3 possibly regulates cellularevents in PDL.
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Report
(4 results)
Research Products
(13 results)
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[Journal Article] Sox9 expression during fracture repair2011
Author(s)
Shintaku Y., Murakami T., Yanagita T., Kawanabe N., Fukunaga T., Matsuzaki K., Uematsu S., Yoshida Y., Kamioka H., Takano-Yamamoto T., Takada K., Yamashiro T
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Journal Title
Cells Tissues Organs
Volume: 194
Issue: 1
Pages: 38-48
DOI
Related Report
Peer Reviewed
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