| Project/Area Number |
22592284
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Orthodontic/Pediatric dentistry
|
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| Research Institution | Okayama University |
|---|
Principal Investigator |
NAKAI Yukie 岡山大学, 大学院・医歯薬学総合研究科, 助教 (70284073)
|
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| Research Collaborator |
SHINGA-ISHIHARA Chikako 岡山大学, 岡山大学病院, 医員
MURAKAMI Kaori 岡山大学, 岡山大学病院, 医員
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| Project Period (FY) |
2010 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
|
|---|
| Keywords | 糖アルコール / 全身疾患 / 口腔ケア / 粘膜保湿 / ミュータンスレンサ球菌 / 病診連携 / 齲蝕 / 口腔粘膜 |
|---|
| Research Abstract |
Oral mucositis is a very frequent and potentially severe complication experienced by patients receiving chemotherapy and/or radiotherapy, which often leads to significant morbidity and mortality, and decreased quality oflife, and is very costly. The condition of dry mouth is also influential in occurrence of caries, periodontal disease and fungal infection. Despite its severity and prevalence, there has been no standard management especially in children. This study evaluated the feasibility of a xylitol spray for the child patients with systemic disease. The results suggest that a xylitol spray is effective on reduction of MS levels in saliva and plaque, and enhancing oral moisture, which leads to improvement of oral conditions.
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