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Molecular biological investigation of periodontal ligament homeostasis in Slc39a13/Zip13 mice

Research Project

Project/Area Number 22592302
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Orthodontic/Pediatric dentistry
Research InstitutionTsurumi University

Principal Investigator

IDAIRA Yayoi  鶴見大学, 歯学部, 学内講師 (40200018)

Co-Investigator(Kenkyū-buntansha) ASADA Yoshinobu  鶴見大学, 歯学部, 教授 (20184145)
SHIMODA Shinji  鶴見大学, 歯学部, 教授 (30139620)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords歯根膜 / 象牙質 / 歯槽骨 / 線維性結合組織 / 歯根 / Zip13,HE / TEM / Zip13 / コラーゲン線維 / H.E染色 / 鍍銀染色 / 免疫染色 / 歯根形成 / レーザーマイクロダイセクション / コラーゲン / マイクロアレイ / HE所見 / 非コラーゲン性たんぱく質 / 二次電子像
Research Abstract

The aim of our study was to investigate the role of Zip13 in the metabolism of periodontalligament. To examine the biological role of Zip13, we performed the morphologicobservation for Achilles tendon and sagittal suture at the cranium which are comprised of fibrous connective tissue as well as periodontal ligament using H&E staining, silverimpregnation and transmission electron microscope (TEM) and immunostaining. Ourresults reveal Zip13 may play an important role to periodontal ligament homeostasis.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (5 results)

All 2013 2010

All Presentation (5 results)

  • [Presentation] 歯根膜線維の代謝・維持に関 わる Zip13 の役割について2013

    • Author(s)
      伊平弥生
    • Organizer
      日本小児歯科学会
    • Place of Presentation
      岐阜国際会議場(岐阜)
    • Related Report
      2012 Final Research Report
  • [Presentation] 歯根象牙質の形成過程におけ る亜鉛トランスポーターZip13 の役割について2013

    • Author(s)
      宗正隆明
    • Organizer
      日本小児歯科学会
    • Place of Presentation
      岐阜国際会議場(岐阜)
    • Related Report
      2012 Final Research Report
  • [Presentation] 歯根膜線維の代謝・維持に関わるZip13の役割について2013

    • Author(s)
      伊平弥生
    • Organizer
      日本小児歯科学会
    • Place of Presentation
      岐阜国際会議場(岐阜県)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 歯根象牙質の形成過程における亜鉛トランスポーターZip13の役割について2013

    • Author(s)
      宗正隆明
    • Organizer
      日本小児歯科学会
    • Place of Presentation
      岐阜国際会議場(岐阜県)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Zip13KOマウスに見られた歯根形成異常に対する形態学的観察2010

    • Author(s)
      伊平弥生
    • Organizer
      日本小児歯科学会
    • Place of Presentation
      郡山市民文化センター(福島県)
    • Year and Date
      2010-12-02
    • Related Report
      2010 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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