| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Research Abstract |
The purpose of this study is to development new bioabsorbed mesh onplant system for orthodontic anchorage. Demineralized dentin matrix (DDM), an organic material derived from the dentine of bovine teeth, was grafted in rat skull defects to determine its bone regeneration ability and the possibility of its use as a bone substitute for bioabsorbed mesh onplant system. In conclusion, DDM may be a useful bone substitute that serves as a scaffold for bone regeneration by inducing a high level of new bone formation soon after surgery. The purpose of the second study was to identify the effect of Reveromucin A (RMA) on inhibiting bone resorption in OPG-/- mice. These data was suggested that RMA normalizes bone metabolism and loss of alveolar bone during continuous tooth movement in OPG-/- mice.This study concluded that RMA has possibility of the bioabsorbed mesh onplant system.
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