Categorization of the bacterial non-coding RNAs and development of the custom array
| Project/Area Number |
22592320
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Periodontal dentistry
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| Research Institution | Nihon University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 歯周病 / 細菌 / non-coding RNA / マイクロアレイ / 核酸 / 遺伝子発現 / 診断 / アレイ / 臨床サンプル / ストレス / カタログ化 |
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| Research Abstract |
For the purpose of development of the custom array for diagnoses to predict a risk of the periodontal disease, we paid attention the bacteria small non-coding RNAs as new targets of the diagnosis probes because they are associated with the bacterial pathogenic expressions and are hard to be disintegrated. Expressed RNAs in P. gingivalis were analyzed by a next - generation DNA sequencer cyclopedically. Several hundred kinds could be confirmed including predicted non-coding RNA in cilico. They are going to be utilizedas microarrays probe in future.
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Report
(4 results)
Research Products
(4 results)
