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The elucidation of the cause of adult caries based on the comprehensive analysis of plaque microbita

Research Project

Project/Area Number 22592337
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Social dentistry
Research InstitutionKyushu University

Principal Investigator

SHIBATA Yukie  九州大学, 大学院・歯学研究院, 助教 (30274476)

Co-Investigator(Kenkyū-buntansha) YAMASHITA Yoshihisa  九州大学, 大学院・歯学研究院, 教授 (20192403)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywordsう蝕 / デンタルプラーク / Gemella属 / クローンライブラリー法 / 細菌叢 / Streptococcus mutans / アピストレップ20 / 齲蝕 / T-RFLP法
Research Abstract

The distribution rate of Gemella in the plaque of the caries-free group showed the high tendency compared with that of the caries-experienced group. In the plaque of the caries-free group, G. haemolysans was detected predominantly duringthe biofilm formation stage. On the other hand, in the plaque of caries-experienced group,G. morbillorum and G. sanguinis were detected by the high ratio in the late stage, while G. haemolysans showed the high distribution rate in the early stage. These results indicate that the distribution rates of Gemella and Gemella spieces in a plaque differ between both groups, suggesting that Gemella may be involved in caries incidence.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (3 results)

All 2013 2012 Other

All Presentation (3 results)

  • [Presentation] う蝕未経験者とう蝕多発者のプラークにおけるGemella属菌種構成の違い2013

    • Author(s)
      李 丹、柴田幸江、竹 下 徹、山下喜久
    • Organizer
      第62回日本口腔衛生学会・総会
    • Place of Presentation
      松本市
    • Year and Date
      2013-05-17
    • Related Report
      2012 Annual Research Report 2012 Final Research Report
  • [Presentation] う蝕未経験者に特徴的なデンタルプラークの構成細菌種2012

    • Author(s)
      李 丹、柴田幸江、竹 下 徹、安井雅樹、山下喜久
    • Organizer
      第34回九州口腔衛生学会
    • Place of Presentation
      鹿児島市
    • Year and Date
      2012-10-07
    • Related Report
      2012 Final Research Report
  • [Presentation] う蝕未経験者に特徴的なデンタルプラークの構成細菌種

    • Author(s)
      李 丹
    • Organizer
      第34回九州口腔衛生学会
    • Place of Presentation
      鹿児島市
    • Related Report
      2012 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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