The elucidation of the cause of adult caries based on the comprehensive analysis of plaque microbita
Project/Area Number |
22592337
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Social dentistry
|
Research Institution | Kyushu University |
Principal Investigator |
SHIBATA Yukie 九州大学, 大学院・歯学研究院, 助教 (30274476)
|
Co-Investigator(Kenkyū-buntansha) |
YAMASHITA Yoshihisa 九州大学, 大学院・歯学研究院, 教授 (20192403)
|
Project Period (FY) |
2010 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
|
Keywords | う蝕 / デンタルプラーク / Gemella属 / クローンライブラリー法 / 細菌叢 / Streptococcus mutans / アピストレップ20 / 齲蝕 / T-RFLP法 |
Research Abstract |
The distribution rate of Gemella in the plaque of the caries-free group showed the high tendency compared with that of the caries-experienced group. In the plaque of the caries-free group, G. haemolysans was detected predominantly duringthe biofilm formation stage. On the other hand, in the plaque of caries-experienced group,G. morbillorum and G. sanguinis were detected by the high ratio in the late stage, while G. haemolysans showed the high distribution rate in the early stage. These results indicate that the distribution rates of Gemella and Gemella spieces in a plaque differ between both groups, suggesting that Gemella may be involved in caries incidence.
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Report
(4 results)
Research Products
(3 results)