• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Delirium onset related to autonomic nervous system disorder caused by aging, illness and/or the environment (noise, blue-ray)

Research Project

Project/Area Number 22592476
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Clinical nursing
Research InstitutionKyushu University of Nursing and Social Welfare

Principal Investigator

HIGUCHI Makie  九州看護福祉大学, 看護福祉学部, 教授 (80040187)

Co-Investigator(Renkei-kenkyūsha) YAMANOTO Keiko  九州看護福祉大学, 看護福祉学部, 教授 (60274982)
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
KeywordsA重篤・救急看護学 / せん妄 / 集中治療室(ICU) / 認知症高齢者 / 外部環境 / ストレス / 青色照明 / 自律神経系活性 / 日内変動 / 青色証明 / 日内リズム / 心拍変動パワースペクトル解析 / 集中治療室(ICU)入室患者 / 腹部大動脈瘤開腹術患者 / ICU騒音 / 耳栓
Research Abstract

Length of hospital stay and mortality rates are significantly higher in delirium patients than in non-delirium patients. A high incidence of postoperative delirium onset has been reported among abdominal aortic aneurysm patients. Patients admitted to the intensive care unit (ICU) also sometimes experience a condition of delirium. The patients are exposed to an stressful environment; they are isolated from their families, and their sleep is disrupted by continuous noise and lighting. Our investigation revealed that noise in the ICU was markedly higher than in the general wards and there were no circadian variations. In the present study, postabdominal aortic aneurysm laparotomy ICU-patients were randomly divided into two groups: a group using earplugs; and a control group without earplugs. Stress caused by the ICU environment (noise) during ICU stay was assessed by non-invasive measurement of heart rate and autonomic nervous system activity (ANS) and their circadian variations. Delirium and/or agitation decreased to 27% in the ICU patients fitted with earplugs from 50% in one without earplugs. Where delirium and/or agitation were observed in ICU patients whose circadian rhythms disappeared or reversed in their ANS and HR, the circadian rhythm in the HR recovered from irregularity in post-ICU ward care, while the ANS did not recover even5 days later. The results indicate that nighttime use of earplugs in the ICU patients reduces onset of delirium and/or agitation, implying that noise from the ICU backgroundnoise plays a part in delirium onset.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (16 results)

All 2012 2011 2010

All Presentation (14 results) Book (2 results)

  • [Presentation] Prevention of delirium in ICU patients through night-time earplug use2012

    • Author(s)
      MAKIE HIGUCHI、YOUHEI TAKAYAMA
    • Organizer
      The 29th Annual Meeting of the International Society for Heart Research Japanese Section
    • Place of Presentation
      Fukuoka
    • Year and Date
      2012-10-26
    • Related Report
      2012 Final Research Report
  • [Presentation] Night-time earplug application to prevent delirium in ICU patients2012

    • Author(s)
      YOUHEI TAKAYAMA、MAKIE HIGUCHI
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      京都
    • Year and Date
      2012-03-15
    • Related Report
      2012 Final Research Report
  • [Presentation] Night-time Earplug Application to Prevent Delirium in ICU Patients2012

    • Author(s)
      Youhei Takayama, Makie Higuchi
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      京都国際会議場(京都)(J Pharmcol Sci 2012 ; 118 (Suppl.1) : p.195P)
    • Year and Date
      2012-03-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] The LV stiffness during underperfusion and reperfusion in diabetic rat hearts with calcitonin gene-related peptide (CGRP)2011

    • Author(s)
      Makie Higuchi, Takamoto Akamine
    • Organizer
      The 28th Annual Meeting of the International Society for Heart Research Japanese Section
    • Place of Presentation
      学術総合センター(東京)(Scientific Program & Content. p103, 2011)
    • Year and Date
      2011-12-03
    • Related Report
      2011 Annual Research Report
  • [Presentation] 集中治療(ICU)の外部環境(騒音・照度)特性とせん妄発症2011

    • Author(s)
      高山洋平、緒方浩志、陶山克洋、樋口マキヱ
    • Organizer
      第64回日本薬理学会西南部会
    • Place of Presentation
      KKRホテル博多(福岡)(日本薬理学雑誌2012;139(3):34P)
    • Year and Date
      2011-11-20
    • Related Report
      2011 Annual Research Report
  • [Presentation] 集中治療室(ICU)の外部環境(騒音・照度)特性とせん妄発症2011

    • Author(s)
      高山洋平、緒方浩志、陶山克洋、樋口マキヱ
    • Organizer
      第64回日本薬理学会西南部会
    • Place of Presentation
      福岡
    • Year and Date
      2011-11-15
    • Related Report
      2012 Final Research Report
  • [Presentation] Autonomic nervous system activity,heart rate and circadian rhythm of the elderly with dementia2011

    • Author(s)
      MAKIE HIGUCHI、YAYOI KAGO
    • Organizer
      第84回日本薬理学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2011-03-24
    • Related Report
      2012 Final Research Report
  • [Presentation] Autonomic nervous system activity, heart rate and circadian rhythm of the elderly with dementia.2011

    • Author(s)
      Makie Higuchi, Yayoi Kago
    • Organizer
      第84回日本薬理学会年会
    • Place of Presentation
      横浜(東北大震災で誌上発表になる)
    • Year and Date
      2011-03-24
    • Related Report
      2010 Annual Research Report
  • [Presentation] The LV stiffness during underperfusion and reperfusion in diabetic rat hearts with calcitonin gene-related peptide (CGRP)2011

    • Author(s)
      MAKIE HIGUCHI、TAKAMOTO AKAMINE
    • Organizer
      The 28th Annual Meeting of the Japanese Section of the International Society for Heart Research
    • Place of Presentation
      Tokyo
    • Related Report
      2012 Final Research Report
  • [Presentation] Effects of calcitonin gene-related peptide (CGRP) on the underperfusion with norepinephrine injuries in diabetic rat hearts2010

    • Author(s)
      MAKIE HIGUCHI、TAKAMOTO AKAMINE
    • Organizer
      The 16th World Congress of Basic and Clinical Pharmacology
    • Place of Presentation
      Copenhagen
    • Year and Date
      2010-07-19
    • Related Report
      2012 Final Research Report
  • [Presentation] Effects of calcitonin gene-related peptide (CGRP) on the underperfusion with norepinephrine injuries in diabetic rat hearts2010

    • Author(s)
      Makie Higuchi, Takamoto Akamine
    • Organizer
      The 16th World Congress of Basic and Clinical Pharmacology
    • Place of Presentation
      Denmark (Copenhagen)
    • Year and Date
      2010-07-19
    • Related Report
      2010 Annual Research Report
  • [Presentation] Microcirculation during underperfusion and reperfusion in diabetic hearts with dopamine2010

    • Author(s)
      MAKIE HIGUCHI
    • Organizer
      The XX World Congress of the International Society for Heart Research
    • Place of Presentation
      Kyoto
    • Year and Date
      2010-05-16
    • Related Report
      2012 Final Research Report
  • [Presentation] Microcirculation during underperfusion and reperfusion in diabetic hearts with dopamine.2010

    • Author(s)
      Makie Higuchi
    • Organizer
      The XX World Congress of the International Society for Heart Research
    • Place of Presentation
      京都国際会議場(京都)
    • Year and Date
      2010-05-16
    • Related Report
      2010 Annual Research Report
  • [Presentation] Effects of dopamine on the microcirculation and stiffness in underperfused diabetic rat hearts2010

    • Author(s)
      MAKIE HIGUCHI、YU-SUKE TAIRA、 RIKIYA KOUCHI、HIROTAKA ASAKAI
    • Organizer
      第83回日本薬理学会年会
    • Place of Presentation
      大阪
    • Related Report
      2012 Final Research Report
  • [Book] コメデイカルのための薬理学第2版2012

    • Author(s)
      樋口マキヱ
    • Publisher
      朝倉書店
    • Related Report
      2012 Final Research Report
  • [Book] コメデイカルのための薬理学 第2版2012

    • Author(s)
      樋口マキヱ
    • Publisher
      朝倉書店
    • Related Report
      2012 Annual Research Report

URL: 

Published: 2010-08-23   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi