Search and analysis of bioactive peptides from a spider venom gland

• Project/Area Number: 22603016
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: ケミカルバイオロジー
• Research Institution: National Institute of Advanced Industrial Science and Technology
• Principal Investigator: KIMURA Tadashi 独立行政法人産業技術総合研究所, バイオメディカル研究部門, 主任研究員 (60344214)
• Co-Investigator(Kenkyū-buntansha): KUBO Tai 独立行政法人産業技術総合研究所, バイオメディカル研究部門, 主任研究員 (10178030)
• Project Period (FY): 2010 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000); Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2010: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
• Keywords: タランチュラ / 毒腺 / 生理活性ペプチド / トランスクリプトーム解析 / 毒液 / 次世代シーケンス / スキャフォールド / cDNAライブラリー / トランスクリプトーム

Research Abstract

Tarantula venom glands produce a large variety of bioactive peptides. We tried to identify the venom components obtained by sequencing clones isolated from a cDNA library prepared from the venom glands of the Chilean common tarantula, Grammostola rosea. T

Research Products

• [Journal Article] Molecular Cloning and Sequence Analysis of the cDNAs Encoding Toxin-Like Peptides from the Venom Glands of Tarantula Grammostola rosea (2012)
  • Author(s): Tadashi Kimura, Seigo Ono and Tai Kubo
  • Journal Title: International journal of peptides Volume: Vol. 2012 Pages: 731293-731293
  • DOI: 10.1155/2012/731293
  • Peer Reviewed
• [Remarks]
  • URL: http://www.aist.go.jp/aist_j/openlab/catalog.html
• [Remarks]
  • URL: http://www.aist.go.jp/aist_j/announce/au2010/aul104/au1104.html
• [Remarks]
  • URL: http://academy.fureai.or.jp/showcase/10/index.html
• [Remarks]
  • URL: http://staff.aist.go.jp/tadashi.kimura/