• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Development of high precision beam intensity control method for decreasing irradiation time in particle cancer therapy

Research Project

Project/Area Number 22611006
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Medical Physics/Radiological Technology
Research InstitutionGunma University

Principal Investigator

TORIKAI Kouta  群馬大学, 先端科学研究指導者育成ユニッ ト, 助教 (90443077)

Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Keywords粒子線治療 / シンクロトロン / ビーム物理 / 加速制御 / パルス電圧 / 重粒子線治療 / 加速器物理学 / 医学物理学 / ビーム取り出し技術 / ビーム強度制御 / 誘導加速技術 / 加速器 / 医学物理 / 自動制御 / DSP
Research Abstract

This study aims for surveying ultra-fast beam extraction control method in synchrotron. A basic idea is proposed by K. Torikai et al. in 2009. The extracted beam by “third-resonance" has time structure, which contains strong beam intensity peak. The frequency of the peak is around 50Hz to 500Hz. The proposed method uses pulse-shape acceleration voltage in order to control the third-resonance condition andΔp/p.
In this study, a repetition rate of 6MHz, maximum pulse voltage of 100V, pulse-timing accuracy of 2nsec power supply is assembled. When this power supply is installed in synchrotron, it serves for turn-by-turn controlling beam current and On/Off of extraction. Beam circulation frequency in synchrotron for particle therapy is around few or several MHz, and this proposed method provides beam control of few 10 times faster than current control method. This method serves for shortening the irradiation time by 1/10,especially in layer-stacking irradiation method. The power supply, control software and simulation system was assembled through this study.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (31 results)

All 2013 2012 2011 2010 Other

All Journal Article (13 results) (of which Peer Reviewed: 8 results) Presentation (7 results) (of which Invited: 1 results) Book (2 results) Remarks (3 results) Patent(Industrial Property Rights) (6 results) (of which Overseas: 1 results)

  • [Journal Article] Three-fraction Cyberknife radiotherapy for brain metastases in critical areas: referring to the risk evaluating radiation necrosis and the surrounding brain volumes circumscribed with a single dose equivalence of 14Gy (V14)2013

    • Author(s)
      Hiroshi K. INOUE
    • Journal Title

      Journal of Radiation Research

      Volume: 54(3) Issue: 4 Pages: 1-9

    • DOI

      10.1093/jrr/rrt006

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Three-dimensional and Multienergy Gamma-ray Simultaneous Imaging by Using a Si/CdTe Compton Camera.2013

    • Author(s)
      Suzuki Y
    • Journal Title

      Radiology

      Volume: 267(3) Issue: 3 Pages: 941-947

    • DOI

      10.1148/radiol.13121194

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 処方箋とRFIDを組み合わせた薬剤部調剤ステータスの自動可視化2013

    • Author(s)
      鳥飼幸太
    • Journal Title

      月刊自動認識

      Volume: 26(1) Pages: 1-6

    • Related Report
      2012 Annual Research Report
  • [Journal Article] Beam range estimation by measuring bremsstrahlung2012

    • Author(s)
      Yamaguchi M, Torikai K, Kawachi N,Shimada H, Satoh T, Nagao Y, Fujimaki S, Kokubun M, Watanabe S, Takahashi T, Arakawa K, Kamiya T, Nakano T
    • Journal Title

      Phys Med Biol

      Volume: 21;57(10) Pages: 2843-56

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] a histone acetyltransferase inhibitor2012

    • Author(s)
      Oike T, Ogiwara H, Torikai K, Nakano T, Yokota J, Kohno T.Garcinol
    • Journal Title

      radiosensitizes cancer cells by inhibiting non-homologous end joining. Int J Radiat Oncol Biol Phys

      Volume: 1;84(3) Pages: 815-21

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Beam range estimation by measuring bremsstrahlung.2012

    • Author(s)
      Yamaguchi M
    • Journal Title

      Phys Med Biol

      Volume: 57(10) Issue: 10 Pages: 2843-2856

    • DOI

      10.1088/0031-9155/57/10/2843

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Garcinol, a histone acetyltransferase inhibitor, radiosensitizes cancer cells by inhibiting non-homologous end joining.2012

    • Author(s)
      Oike T
    • Journal Title

      Int J Radiat Oncol Biol Phys

      Volume: 84(3) Issue: 3 Pages: 815-821

    • DOI

      10.1016/j.ijrobp.2012.01.017

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Tele-Viewer System of Treatment Planning of Heavy-ion Cancer Therapy2012

    • Author(s)
      Kota Torikai
    • Journal Title

      Japanese Journal of Telemedicine and Telecare

      Volume: 8(2) Pages: 307-318

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Suppression of HIF-1α expression and radiation resistance in acute hypoxic conditions2011

    • Author(s)
      Takahiro Oike, Yoshiyuki Suzuki, Wael Al-Jahdari, Abdulelah Mobaraki, Jun-Ichi Saitoh, Kohta Torikai, Katsuyuki Shirai, Takashi Nakano
    • Journal Title

      Experimental and Therapeutic Medicine

      Volume: 3 Issue: 1 Pages: 141-145

    • DOI

      10.3892/etm.2011.373

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] SUB-mm THERAPEUTIC CARBON-ION IRRADIATION PORT IN GUNMA UNIVERSITY2011

    • Author(s)
      Kota Torikai, Satoru Yamada, Tatsuaki Kanai, Eri Takeshita, Ken Yusa, Mutsumi Tashiro, Hirofumi Shimada, Takashi Nakano
    • Journal Title

      Proceedings of IPAC2011

      Volume: 3 Pages: 3607-3609

    • Related Report
      2011 Annual Research Report
  • [Journal Article] Cloud・DELPHI導入による病院間重粒子線治療計画連携2011

    • Author(s)
      鳥飼幸太, ほか8名
    • Journal Title

      日本遠隔医療学会

      Volume: 2011春(印刷中)

    • Related Report
      2010 Annual Research Report
  • [Journal Article] 群馬大学重粒子線医学センターでのRFID導入2011

    • Author(s)
      鳥飼幸太, ほか2名
    • Journal Title

      平成22年度大学病院情報マネジメント部門連絡会議

      Volume: 30(印刷中)

    • Related Report
      2010 Annual Research Report
  • [Journal Article] 群馬大学重粒子線医学研究センター2010

    • Author(s)
      鳥飼幸太, ほか12名
    • Journal Title

      日本加速器学会誌

      Volume: 1(印刷中)

    • Related Report
      2010 Annual Research Report
  • [Presentation] 重粒子線治療計画連携システムの進捗状況2013

    • Author(s)
      鳥飼幸太
    • Organizer
      JTTA Spring Conference 2013 (日本遠隔医療学会)
    • Place of Presentation
      全国家電会館
    • Related Report
      2012 Annual Research Report
  • [Presentation] Sub-mm Therapeutic Carbon-ion Irradiation Port In Gunma University2012

    • Author(s)
      Kota Torikai, Satoru Yamada, Tatsuaki Kanai, Eri Takeshita, Ken Yusa, Mutsumi Tashiro, Hirofumi Shimada, Takashi Nakano
    • Organizer
      International Conference on ParticleAccelerator Conference 2011
    • Place of Presentation
      クルーサル会議場(IPAC'11)(サンセバスチャン、スペイン)
    • Year and Date
      2012-09-08
    • Related Report
      2012 Final Research Report
  • [Presentation] 医療用コンプトンカメラの開発2012

    • Author(s)
      鳥飼幸太
    • Organizer
      学振168委員会:「放射線科学とその応用」
    • Place of Presentation
      東大本郷キャンパス(東京都文京区本郷7-3-1)工学部2号館210室
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 中野隆史腫瘍細胞密度の位置依存モデルによるTCP維持とCTV端での線量低減の両立可能性解析2011

    • Author(s)
      鳥飼幸太、加藤弘之、安藤興一、吉田由香里、金井達明
    • Organizer
      神戸ポートピアホテル会議場
    • Place of Presentation
      神戸市、兵庫県
    • Year and Date
      2011-11-18
    • Related Report
      2012 Final Research Report
  • [Presentation] SUB-mm THERAPEUTIC CAEBON-ION IRRADIATION PORT IN GUNMA UNIVERSITY2011

    • Author(s)
      Kota Torikai
    • Organizer
      Internationak Particle Accelerator Conference 2011
    • Place of Presentation
      San Sebastian, Spain
    • Year and Date
      2011-09-05
    • Related Report
      2011 Annual Research Report
  • [Presentation] Cloud-DELPHI導入による病院間重粒子線治療計画連携2011

    • Author(s)
      鳥飼幸太
    • Organizer
      日本遠隔医療学会
    • Place of Presentation
      東京都文京区全国家電会館
    • Year and Date
      2011-02-19
    • Related Report
      2010 Annual Research Report
  • [Presentation] シンポジウム・ユーザからみたESI2011

    • Author(s)
      鳥飼幸太
    • Organizer
      日本高精度外部放射線照射研究会
    • Place of Presentation
      秋葉原コンベンションホール
    • Year and Date
      2011-02-11
    • Related Report
      2010 Annual Research Report
  • [Book] 放射線外科 治療の進歩2012

    • Author(s)
      Textbook of Radiosurgery
    • Publisher
      メディカ出版、井上洋編
    • Related Report
      2012 Final Research Report
  • [Book] Rad Fan 2012 March Vol.102012

    • Author(s)
      鳥飼幸太、大野達也、加藤弘之、北田陽子、田巻倫明、石居隆義、小屋順一、島田博文、中野隆史
    • Total Pages
      100
    • Publisher
      株式会社メディカルアイ
    • Related Report
      2011 Annual Research Report
  • [Remarks]

    • URL

      http://asrldu.dept.med.gunma-u.ac.jp/ktorikai/kouta_torikai.html

    • Related Report
      2012 Final Research Report
  • [Remarks] 自動認識システム大賞

    • URL

      http://www.jaisa.jp/award/history.html

    • Related Report
      2012 Annual Research Report
  • [Remarks]

    • URL

      http://asrldu.dept.med.gunma-u.ac.jp/ktorikai/kouta_torikai.html

    • Related Report
      2011 Annual Research Report
  • [Patent(Industrial Property Rights)] 冷却装置及び放射線検出装置2013

    • Inventor(s)
      中野隆史、鳥飼幸太、荒川和夫
    • Industrial Property Rights Holder
      群馬大学、株式会社テクノアソシエ
    • Industrial Property Number
      2013-013272
    • Filing Date
      2013-01-28
    • Related Report
      2012 Final Research Report
  • [Patent(Industrial Property Rights)] 冷却装置及び放射線検出装置2013

    • Inventor(s)
      中野隆史、鳥飼幸太、荒川和夫
    • Industrial Property Rights Holder
      中野隆史、鳥飼幸太、荒川和夫
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-01-28
    • Related Report
      2012 Annual Research Report
  • [Patent(Industrial Property Rights)] 調剤管理システム2012

    • Inventor(s)
      鳥飼幸太、阿部正樹、岡正俊
    • Industrial Property Rights Holder
      群馬大学、トッパン・フォームズ株式会社
    • Filing Date
      2012-11-01
    • Related Report
      2012 Final Research Report
  • [Patent(Industrial Property Rights)] 粒子線モニタリング装置、粒子線モニ タリングプログラム及び粒子線モニタリン グ方法2012

    • Inventor(s)
      鳥飼幸太、阿部正樹、岡正俊
    • Industrial Property Rights Holder
      群馬大学、トッパン・フォームズ株式会社
    • Filing Date
      2012-11-01
    • Related Report
      2012 Final Research Report
  • [Patent(Industrial Property Rights)] 調剤管理システム2012

    • Inventor(s)
      鳥飼幸太、阿部正樹
    • Industrial Property Rights Holder
      鳥飼幸太、阿部正樹
    • Industrial Property Rights Type
      特許
    • Filing Date
      2012-11-01
    • Related Report
      2012 Annual Research Report
  • [Patent(Industrial Property Rights)] ビーム照射装置及びビーム照射制御方法2010

    • Inventor(s)
      鳥飼幸太, 山田敏
    • Industrial Property Rights Holder
      群馬大学
    • Filing Date
      2010-10-08
    • Related Report
      2010 Annual Research Report
    • Overseas

URL: 

Published: 2010-08-23   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi