Establishment of fluorescent in vivo Western method
Project/Area Number |
22650092
|
Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
Allocation Type | Single-year Grants |
Research Field |
Laboratory animal science
|
Research Institution | University of Tsukuba |
Principal Investigator |
|
Co-Investigator(Kenkyū-buntansha) |
TANAKA Junko 筑波大学, 医学医療系, 助教 (30517793)
|
Project Period (FY) |
2010 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥3,320,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2010: ¥1,500,000 (Direct Cost: ¥1,500,000)
|
Keywords | イメージング / 近赤外 / 蛍光 / 動物実験技術 / 分子認識 / バイオテクノロジー / 遺伝子組換え / 細胞・組織 / 神経科学 |
Research Abstract |
Fluorescent real-time imaging methods enables us to monitor proteins and other molecules in living animals. This technique can make significant contribution to not only basic science but also researches for drug discovery, regenerative medicine and clinical state analyses in model animals. For this purpose, we succeeded to develop a non-fluorescent in near-infrared and nutritionally complete diet and a fluorescent protein derivative which shows 30-fold higher intensity of NIR fluorescence.
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Report
(3 results)
Research Products
(31 results)