Creation of functional cell aggregates confaining bioabsobable hydrogel microspheres for regenerative therapy and research
| Project/Area Number |
22650110
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | Kyoto University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
YAMAMOTO Masaya 京都大学, 再生医科学研究所, 准教授 (10332735)
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥3,290,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥1,600,000 (Direct Cost: ¥1,600,000)
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| Keywords | ゼラチン / ハイドロゲル微粒子 / 骨髄由来間葉系幹細胞 / 細胞集合体 / 代謝活性 / 細胞生存率 / L-乳酸産生量 / グルコース消費量 / ハイドロゲル微粒 |
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| Research Abstract |
When cultured with gelatin hydrogel microspheres, rat bone marrow-derived mesenchymal stem cells formed aggregates homogeneously incorporating the microspheres. The viability of the cell aggregates and the extent of osteogenic differentiation were significantly higher compared with those of aggregates formed without microspheres.
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Report
(3 results)
Research Products
(9 results)
