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Development of a new stress assessment system using cardiorespiratory coupling index

Research Project

Project/Area Number 22650155
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeSingle-year Grants
Research Field Applied health science
Research InstitutionYamagata University

Principal Investigator

NIIZEKI Kyuichi  山形大学, 大学院・理工学研究科, 教授 (00228123)

Research Collaborator SAITOH Tadashi  山形大学, 大学院・理工学研究科, 助教 (20454770)
Project Period (FY) 2010 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥2,660,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥1,100,000 (Direct Cost: ¥1,100,000)
Keywordsストレスマネジメント / カップリング / 位相同期 / 呼吸性不整脈 / 精神課題 / 唾液アミラーゼ / クロモグラニン
Research Abstract

We proposed a new psychological stress index using the phase-lag variations between respiratory sinus arrhythmia (RSA) and breathing. Heart rate (HR), systolic blood pressure, and breathing frequency (f_R) increased in response to mental arithmetic test, while the amplitude of RSA (A_<RSA>), high-frequency (HF) component of HR variability (HRV) and the degree of phase synchronization (λ) between RSA and breathing decreased. The λ was correlated with normalized A_<RSA> and the HF power of HRV, and was inversely related with normalized low-frequency (LF) component to HF ratio. In addition, λ was not susceptible to f_R influence. It is suggested that the λ could be a marker for assessing the interaction between psychological states and autonomic control.

Report

(3 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • Research Products

    (31 results)

All 2012 2011 2010 Other

All Journal Article (12 results) (of which Peer Reviewed: 11 results) Presentation (15 results) Book (2 results) Remarks (1 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] Incoherent oscillations of respiratory sinus arrhythmia during acute mental stress in humans2012

    • Author(s)
      Niizeki K, Saitoh T.
    • Journal Title

      American Journal of Physiology Heart and Circulatory Physiology

      Volume: Vol.302, No.1 Issue: 1 Pages: 359-367

    • DOI

      10.1152/ajpheart.00746.2011

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Assessment of mental stress by incoherent oscillations of respiratory sinus arrhythmia2011

    • Author(s)
      Niizeki K, Imano W, Harada N, Saitoh T.
    • Journal Title

      Proceedings of 8^<th> International Conference on Ubiquitous Healthcare

      Volume: Vol.8 Pages: 49-52

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Non-invasive spectral imaging of skinchromophores based on multiple regressionanalysis aided by Monte Carlo simulation2011

    • Author(s)
      Izumi Nishidate, Aditya Wiswadarma, Yota Hase, Noriyuki Tanaka, Takaaki Maeda, Kyuichi Niizeki, and Yoshihisa Aizu
    • Journal Title

      Opt. Lett

      Volume: Vol.36, No.16 Issue: 16 Pages: 3239-3241

    • DOI

      10.1364/ol.36.003239

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Noninvasive imaging of human skinhemodynamics using a digitalred-green-blue camera2011

    • Author(s)
      Izumi Nishidate, Noriyuki Tanaka, TatsuyaKawase, Takaaki Maeda, Tomonori Yuasa, Yoshihisa Aizu, Tetsuya Yuasa, Kyuichi Niizeki
    • Journal Title

      Journal of Biomedical Optics

      Volume: Vol.16 Issue: 8 Pages: 1-14

    • DOI

      10.1117/1.3613929

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effects of lower-leg rhythmic cuff inflation on cardiovascular autonomic responses during quiet standing in healthy subjects2011

    • Author(s)
      Niizeki K, Tominaga T, Saitoh T, Nishidate I, Takahashi T, Uchida K.
    • Journal Title

      American Journal of Physiology Heart and Circulatory Physiology

      Volume: Vol.30, No.5 Pages: 1923-1929

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] 近赤外分光法によるヘモグロビン濃度測定は血流速度変化の影響を受けない2011

    • Author(s)
      齊藤直, 深見忠典, 柳田裕隆, 高橋龍尚, 新関久一
    • Journal Title

      生体医工学

      Volume: 49巻,1号 Pages: 185-190

    • NAID

      130004947421

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Assessment of mental stress by incoherent oscillations of respiratory sinus arrhythmia2011

    • Author(s)
      Niizeki K, Imano K, Harada N, Saitoh T
    • Journal Title

      Proceedings of 8th International Conference on Ubiquitous Healthcare

      Pages: 49-52

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 近赤外分光法によるヘモグロビン濃度測定は血流速度変化の影響を受けない2011

    • Author(s)
      齊藤直, 深見忠典, 柳田裕隆, 新関久一
    • Journal Title

      生体医工学

      Volume: 49 Pages: 185-190

    • NAID

      130004947421

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of lower leg rhythmic cuff inflation on cardiovascular autonomic responses during quiet standing in healthy subjects2011

    • Author(s)
      Niizeki K., Tominaga T., Saitoh T., Nishidate I., Takahashi T., Uchida K.
    • Journal Title

      American Journal of Physiology Heart and Circulatory Physiology

      Volume: 300 Pages: 1923-1929

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Heart rate response to oxygen uptake during graded exercises as an index of cardiopulmonary functional reserve in patients on hemodialysis2010

    • Author(s)
      Watanabe S, Tsuyuki K, Takahashi K, Ebine K, Sakamoto T, Matsuo T, Niizeki K, Takahashi T.
    • Journal Title

      The journal of rehabilitation sport

      Volume: Vol.29 Pages: 2-6

    • NAID

      110007681510

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] 起立時の循環系応答に及ぼす模擬筋ポンプの影響2010

    • Author(s)
      新関久一, 富永貴則, 知久幸之介, 名渕恵美, 齊藤直
    • Journal Title

      第25回生体生理工学シンポジウム論文集

      Volume: Vol.25 Pages: 301-304

    • Related Report
      2011 Final Research Report
  • [Journal Article] Active muscle oxygenation dynamics measured during high-intensity exercise by using two near-infrared spectroscopy methods2010

    • Author(s)
      Saitoh T, Ooue A, Kondoh N, Niizeki K, Koga S.
    • Journal Title

      Advance in Experimental Medicine and Biology

      Volume: Vol.662 Pages: 225-230

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Presentation] 呼吸性不整脈の位相差ゆらぎに基づいたメンタルストレスの評価2012

    • Author(s)
      新関久一, 菊池聖也, 今野稚奈, 原田直季, 齊藤直
    • Organizer
      第23回日本臨床モニター学会総会
    • Place of Presentation
      横浜シンポジア(神奈川県横浜市)
    • Year and Date
      2012-04-21
    • Related Report
      2011 Final Research Report
  • [Presentation] Assessment of mental stress by incoherent oscillations of respiratory sinus arrhythmia2011

    • Author(s)
      Niizeki K, Imano W, Harada N, Saitoh T.
    • Organizer
      Proceedings of 8^<th> International Conference on Ubiquitous Healthcare
    • Place of Presentation
      立命館大学びわこ・くさつキャンパス(滋賀県草津市)
    • Year and Date
      2011-09-22
    • Related Report
      2011 Final Research Report
  • [Presentation] Assessment of mental stress by incoherent oscillations of respiratory sinus arrhythmia2011

    • Author(s)
      Niizeki K, Imano K, Harada N, Saitoh T
    • Organizer
      8th International Conference on Ubiquitous Healthcare
    • Place of Presentation
      立命館大学
    • Year and Date
      2011-09-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] Rhythmic lower-leg cuff inflation enhances cardiovagal reflex during quiet standing in healthy humans2011

    • Author(s)
      Niizeki K, Tominaga T, Chiku K, Nabuchi M, Saitoh T, Uchida K
    • Organizer
      第58回アメリカスポーツ医学会議
    • Place of Presentation
      コロラド,デンバー
    • Year and Date
      2011-05-31
    • Related Report
      2011 Final Research Report
  • [Presentation] Determination of the trends in the hemoglobin concentrations in inactive muscle during cycling exercise2011

    • Author(s)
      Saitoh T, Ishida Y, Matsumoto Y, Okuyama G, Niizeki K
    • Organizer
      第58回アメリカスポーツ医学会議
    • Place of Presentation
      コロラド,デンバー
    • Year and Date
      2011-05-31
    • Related Report
      2011 Final Research Report
  • [Presentation] Rhythmic lower-leg cuff inflation enhances cardiovagal reflex during quiet standing in healthy subjects2011

    • Author(s)
      Niizeki K, Tominaga T, Chiku M, Nabuchi M, Saitoh T, Uchida K
    • Organizer
      58^<th> American College of Sports Medicine
    • Place of Presentation
      Denver Colorado
    • Year and Date
      2011-05-31
    • Related Report
      2011 Annual Research Report
  • [Presentation] Determination of the trends in the hemoglobin concentrations in inactive muscle during cycling exercise2011

    • Author(s)
      Saitoh T, Ishida Y, Matsumoto Y, Okuyama G, Niizeki K
    • Organizer
      58^<th> American College of Sports Medicine
    • Place of Presentation
      Denver Colorado
    • Year and Date
      2011-05-31
    • Related Report
      2011 Annual Research Report
  • [Presentation] 筋収縮由来心拍リズム位相反応特性の抽出2011

    • Author(s)
      原田直季, 百瀬亮, 知久幸之介, 齊藤直, 新関久一
    • Organizer
      第50回日本生体医工学会大会
    • Place of Presentation
      東京電機大学(東京都千代田区)
    • Year and Date
      2011-04-29
    • Related Report
      2011 Final Research Report
  • [Presentation] 三次元加速度による歩行運動時エネルギー代謝動態の推定2011

    • Author(s)
      新沼大樹, 齊藤直, 新関久一
    • Organizer
      第50回日本生体医工学会大会
    • Place of Presentation
      東京電機大学(東京都千代田区)
    • Year and Date
      2011-04-29
    • Related Report
      2011 Final Research Report
  • [Presentation] 起立時の循環系応答に及ぼす模擬筋ポンプの影響2010

    • Author(s)
      新関久一, 富永貴則, 知久幸之介, 名渕恵美, 今野稚奈, 原田直季, 齊藤直
    • Organizer
      第25回生体生理工学シンポジウム
    • Place of Presentation
      岡山大学鹿田キャンパス(岡山県岡山市)
    • Year and Date
      2010-09-23
    • Related Report
      2011 Final Research Report
  • [Presentation] 視聴覚刺激を用いた対人間の心拍リズム間位相同期の解析2010

    • Author(s)
      今野稚奈, 鈴木香理, 齊藤直, 新関久一
    • Organizer
      生体医工学シンポジウム2010
    • Place of Presentation
      北海道大学大学院情報科学研究科(北海道札幌市)
    • Year and Date
      2010-09-11
    • Related Report
      2011 Final Research Report
  • [Presentation] 視聴覚刺激を用いた対人間の心拍リズム間位相同期の解析2010

    • Author(s)
      今野稚奈, 鈴木香理, 齊藤直, 新関久一
    • Organizer
      生体医工学シンポジウム2010
    • Place of Presentation
      北海道大学
    • Year and Date
      2010-09-10
    • Related Report
      2010 Annual Research Report
  • [Presentation] Effect of cognitive task on pulmonary oxygen uptake kinetics during moderate cycling exercise2010

    • Author(s)
      Nabuchi M, Handa M, Chiku K, Saitoh T, Niizeki K.
    • Organizer
      第49回日本生体医工学会大会
    • Place of Presentation
      大阪国際交流センター(大阪府大阪市)
    • Year and Date
      2010-06-27
    • Related Report
      2011 Final Research Report
  • [Presentation] Effect of cognitive task on pulmonary oxygen uptake kinetics during moderate cycling exercise.2010

    • Author(s)
      Nabuchi M., Handa M., Chiku K., Saitoh T., Niizeki K.
    • Organizer
      第49回日本生体医工学会大会
    • Place of Presentation
      大阪国際交流センター
    • Year and Date
      2010-06-27
    • Related Report
      2010 Annual Research Report
  • [Presentation] Muscle deoxygenation dynamics in active and inactive muscles during heavy and moderate cycling exercise2010

    • Author(s)
      Saitoh T, Tomioka K, Muroi H, Niizeki K
    • Organizer
      第87回日本生理学会大会
    • Place of Presentation
      盛岡市民文化ホール(岩手県盛岡市)
    • Year and Date
      2010-05-19
    • Related Report
      2011 Final Research Report
  • [Book] カップリング理論でスマートに2010

    • Author(s)
      新関久一, 野村国彦, 西川正範
    • Total Pages
      105
    • Publisher
      メディカル情報出版社
    • Related Report
      2011 Final Research Report
  • [Book] カップリング理論でスマートに2010

    • Author(s)
      新関久一, 野村国彦, 西川正範
    • Total Pages
      105
    • Publisher
      メディカル情報サービス
    • Related Report
      2010 Annual Research Report
  • [Remarks]

    • URL

      http://ecyber0.yz.yamagata-u.ac.jp/~nzq

    • Related Report
      2011 Final Research Report
  • [Patent(Industrial Property Rights)] 酸素摂取量測定方法およびこの方法を用いる装置2011

    • Inventor(s)
      新関久一, 吉澤保夫
    • Industrial Property Rights Holder
      有限会社タックリサーチ
    • Acquisition Date
      2011-04-08
    • Related Report
      2011 Final Research Report

URL: 

Published: 2010-08-23   Modified: 2016-04-21  

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