| Project/Area Number |
22650158
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Applied health science
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| Research Institution | Okayama University |
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Principal Investigator |
ARAO Yujiro 岡山大学, 大学院・保健学研究科, 教授 (40151146)
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| Research Collaborator |
CHIKASUE Kumiko 岡山大学, 大学院・保健学研究科, 博士
IKEDA Kazuyuki 岡山大学, 大学院・保健学研究科, 修士
AONO Eriko 岡山大学, 医学部・保健学科, 学部学生
OHNISHI Takuma 岡山大学, 医学部・保健学科, 学部学生
KATAYAMA Daisuke 岡山大学, 医学部・保健学科, 学部学生
KAWANISHI Satoru 岡山大学, 医学部・保健学科, 学部学生
TOKUHARA Narumi 岡山大学, 医学部・保健学科, 学部学生
NAGATANI Yuki 岡山大学, 医学部・保健学科, 学部学生
HAGI Mihoko 岡山大学, 医学部・保健学科, 学部学生
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥3,190,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥1,500,000 (Direct Cost: ¥1,500,000)
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| Keywords | 保健健康情報 / 持続感染ウイルス / 核酸 / ヒトヘルペスウイルス6型 / トルケテノウイルス / 感染症 / ストレス / 微生物 / ウイルス / 遺伝子増幅 |
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| Research Abstract |
To prevent healthy persons from onset and deterioration of viral disease, we need to know unknown factors in everyday life increasing virus load in them. The aim of this study is to find such factors by utilizing viruses that is persistently infecting healthy persons and excreted into saliva. I found that practical training in a hospital, job hunting, listening unfavorable music, and reduced sleeping hours significantly heightened the human herpesvirus type 6(HHV6)-positive rate of saliva samples(p<0. 05). I also found that the factors induced the similar increase in the torque teno virus(TTV)-positive rate of saliva samples but the increase was not significant. Sleeping hours also correlated reversely with the TTV-positive rate(r=-0. 71), suggesting that reduction in sleeping hours is an enhancive factor for TTV in saliva in addition to HHV6.
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