| Project/Area Number |
22650225
|
|---|
| Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Carcinogenesis
|
|---|
| Research Institution | 公益財団法人がん研究会 (2011)
Japanese Foundation For Cancer Research (2010) |
|---|
Principal Investigator |
SUGITANI Yoshinobu 公益財団法人がん研究会, ゲノムセンター, 研究員 (80360569)
|
|---|
| Project Period (FY) |
2010 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥3,210,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥2,300,000 (Direct Cost: ¥2,300,000)
|
|---|
| Keywords | 神経前駆細胞 / 多段階発癌 / miRNA / 脳腫瘍 / 細胞分化 / Shhシグナル / 遺伝子発現制御 / in vivoエレクトロポレーション / トランスポゾン / Patched / 髄芽腫 / ニューロン / 遺伝子導入技術 |
|---|
| Research Abstract |
Development and application of new in vivo electroporation method, which is combined with transposon & insulator-based plasmid vector system, opened the door to elucidate that miRNAs are involved in shh-associated medulloblastoma formation.
|
